FÁS Science Challenge
Proposed Intern Programme
2007/2008
› Baylor College of Research and Medicine, Houston
› University of Texas - Health Science Centre, Houston
› Rice Universit...
› Largest Medical Center in the world
› 42 Member Institutions including 11
Educational Institutes
› 22,000 students
Texas...
Internship Opportunities at Institutes in
The Texas Medical Centre
› Baylor College of Medicine
› University of Texas Heal...
Baylor College of Medicine
› No. 1 for research expenditures in biological science by
the National Science Foundation
› 10...
The University of Texas Health Science
Center at Houston (UTHSC-H)
› UTHSC-H is primarily a graduate-level university focu...
Rice University
› Cited as one of “America’s New Ivies”. Rivals for
applicants for Rice University are Stanford, Harvard, ...
Research Projects at Baylor College of
Medicine
#1: The Biological and Cell Signaling Implications of Steroid
Receptor Coa...
Research Projects at Baylor College of
Medicine
#4: Polyomavirus SV40 and Pathogenesis of Human Disease
Mentor: Janet Bute...
Research Projects at University of
Texas Health Science Centre
#1: Transcriptional regulation of soluble guanylyl cyclise
...
Research Projects at Rice University
#1: New Carbon Nanostructures for Molecular Imaging in Medicine
Mentor: Lon Wilson, P...
Internship Opportunities in The Texas
Medical Center
Students will also be involved in ancillary programmes
including:
› A...
Spotlight: Baylor Mentor
› Chairman of Department with an annual budget of over 30 million dollars in research
funding and...
Spotlight: Rice Mentor
› Recipient of the world's 35 Top Young Innovators by Technology Review
Magazine in 2006
› Research...
Spotlight: UTHSC-H Mentor
› Nobel Prize winner in Physiology/Medicine 1998
› World leader in nitric oxide and cyclic GMP c...
Massachusetts Institute of Technology
(M.I.T.) Boston
• Institute Harvard-MIT Health Science and Technology (H.S. & T.)
• ...
Project One: Visual Orientation, Navigation and Spatial
Memory Countermeasures
• Design/development of experiment investig...
Project One: Visual Orientation, Navigation and Spatial Memory
Countermeasures
• Type of Students
Engineering or Cognitive...
Project Two
• Title
Exercise and Gravity, as achieved on a short radius (2m) centrifuge rotating at
up to 1800
/sec. Measu...
Harvard Medical School
• Institute Harvard Medical School (Brigham & Womans Hospital, Boston)
• Department
› Division of S...
Projects
#1: Neurobiology of Individual Differences in Sleep Duration
Mentor: Daniel Aeschbach, Ph.D., Assistant Professor...
Projects
#5: Effect of Light on the Human Circadian System
Mentor: Steven W. Lockley, Ph.D., Assistant Professor of Medici...
Type of Students
• Projects 1 - 5:
Those with an interest in Physiology, Neuroscience and/or Clinical
Research
• Project 6...
Beth Israel Deaconess Medical Centre
(Harvard Medical School)
• Department
› The Integrative Cerebral Hemodynamics Lab. is...
Beth Israel Deaconess Medical Centre
(Harvard Medical School)
• Aims
› To focus on regulation of brain blood flow which is...
Projects
#1: Cerebral Blood Flow and Cardiac Output
#2: Effect of Gravity on Functional Cerebral Blood Flow
#3: Vestibular...
Projects
• Mentors:
All projects are supervised by:
› Jorge Serrador, Ph.D., Dept. of Medicine, Gerontology
› Dr Gosala S....
Florida Institute of Technology
• Department
› Department of Physics, Astrophysics and Space Sciences in the College of
Sc...
Dynamac Corporation
Kennedy Space Centre, Florida
• Dynamac Corporation is a leading provider of research and development
...
Dynamac Corporation
Kennedy Space Centre, Florida
• Mentors
› Garry W. Stutte, Ph.D., Senior Scientist Plant Physiology
› ...
Other Internship Locations
• Ad Astra Technologies, Houston
• Embry-Riddle Aeronautical University, Florida
• Helicopters ...
2005 Intern Student Highlights
Education:
› 3 students completed Masters Degree in Ireland based on
the research carried o...
2005 Intern Student Highlights
Oral Scientific Presentations:
› All Intern students gave oral presentations at a Mini-
Sym...
2005 Intern Student Highlights
Poster Presentations:
› Brita O’ Sullivan, D, Harn, M Reschke and Scott Wood. Tilt and Tran...
2005 Intern Student Highlights
Manuscripts:
› William Hamilton and Austin Cooney. Deciphering the role of GCNF in
regulati...
FÁS Science Challenge October 2006-April 2007 Interns
Student Irish University Mentor US Placement
Emer Lawlor DIT John Ly...
FÁS Science Challenge October 2006-April 2007 Interns
Student Irish University Mentor US Placement
James Mulcahy UCD Chang...
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FÁS Science Challenge Proposed Intern Programme

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FÁS Science Challenge Proposed Intern Programme

  1. 1. FÁS Science Challenge Proposed Intern Programme 2007/2008
  2. 2. › Baylor College of Research and Medicine, Houston › University of Texas - Health Science Centre, Houston › Rice University – Nanotechnology, Houston › Harvard Medical School – Brigham & Woman’s Hospital and Research Centre › Massachusetts Institute of Technology (MIT) - Health, Science & Technology › Beth Israel Deaconess Medical Centre – Harvard Medical School › Florida Institute of Technology › Dynamac Corporation – Kennedy Space Centre › Embry-Riddle Aeronautical University › Ad-Astra Technologies - Houston Locations for Proposed Intern Programme 2007/2008
  3. 3. › Largest Medical Center in the world › 42 Member Institutions including 11 Educational Institutes › 22,000 students Texas Medical Center
  4. 4. Internship Opportunities at Institutes in The Texas Medical Centre › Baylor College of Medicine › University of Texas Health Science Center at Houston (UTHSC-H) › Rice University
  5. 5. Baylor College of Medicine › No. 1 for research expenditures in biological science by the National Science Foundation › 10th overall among the USA top medical schools for research (U.S.News & World Report) › 13th among all USA medical schools for National Institutes of Health funding
  6. 6. The University of Texas Health Science Center at Houston (UTHSC-H) › UTHSC-H is primarily a graduate-level university focusing on the health sciences › $149.6 million in research expenditures › Ranked 56th out of 515 higher education institutions
  7. 7. Rice University › Cited as one of “America’s New Ivies”. Rivals for applicants for Rice University are Stanford, Harvard, MIT and Duke › Rice University is the birthplace of nanotechnology › Rice professors Richard E. Smalley and Robert F. Curl won the 1966 Nobel Prize in Chemistry for their research on nanoparticles
  8. 8. Research Projects at Baylor College of Medicine #1: The Biological and Cell Signaling Implications of Steroid Receptor Coactivators Mentor: Bert W. O’ Malley, M.D. Professor and Chairman, Department of Molecular and Cellular Biology at Baylor College of Medicine. #2: Mouse models to study cancer and reproduction Mentor: Francesco DeMayo, Ph.D., Professor, Department of Molecular and Cellular Biology, Baylor College of Medicine #3: Regulation of embryonic stem cell gene expression and function Mentor: Austin Cooney, Ph.D. Associate Professor, Department of Molecular & Cellular Biology ,Baylor College of Medicine
  9. 9. Research Projects at Baylor College of Medicine #4: Polyomavirus SV40 and Pathogenesis of Human Disease Mentor: Janet Butel, Ph.D., Distinguished Services Professor and Chairman of the Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX. #5: Mouse Models to study Progesterone's role in Mammary Gland Morphogenesis and Tumorigenesis Mentor: John Lydon, Ph.D., Associate Professor, Department of Molecular and Cellular Biology, Baylor College of Medicine #6: Hormonal control of genes that regulate follicular development and ovulation Mentor: Joanne Richards, Ph.D., Professor, Department of Molecular and Cellular Biology, Baylor College of Medicine #7: The role of Nuclear Receptor, NOR-1, in Tumorigenesis Mentor: Orla Conneely, Ph.D., Professor, Department of Molecular and cellular Biology, Baylor College of Medicine
  10. 10. Research Projects at University of Texas Health Science Centre #1: Transcriptional regulation of soluble guanylyl cyclise Mentor: Ferid Murad, M.D, Ph.D., 1998 Nobel Laureate,. Physiology/Medicine. Director Institute of Molecular Medicine; Professor Integrative Biology and Pharmacology UT-Houston Medical School
  11. 11. Research Projects at Rice University #1: New Carbon Nanostructures for Molecular Imaging in Medicine Mentor: Lon Wilson, Ph.D., Professor, Department of Chemistry, Rice University #2: Shaped Nanoparticles: Synthesis, Properties and Reactivity Mentor: Kenton Whitmire, Ph.D., Professor and Chair, Department of Chemistry, Rice University #3: Scalable liquid-phase synthesis of nanoparticles Mentor: Michael Wong, Ph.D., Assistant Professor, Department of Chemical & Biomolecular Engineering, Rice University #4: Developing a rational approach to single walled carbon nanotube growth Mentor:Andrew Barron, Ph.D., Professor, Department of Chemistry, Rice University
  12. 12. Internship Opportunities in The Texas Medical Center Students will also be involved in ancillary programmes including: › Attending lectures and seminars › Auditing graduate level courses Field trips to: › Local high tech companies › NASA/Johnson Space Centre › The Smalley Institute for Nanoscale Science and Technology at Rice University › Human Genome Sequencing Centre at Baylor College of Medicine
  13. 13. Spotlight: Baylor Mentor › Chairman of Department with an annual budget of over 30 million dollars in research funding and which ranks number one in U.S. medical school basic science departments in NIH funding (without clinical component) › World leader in Steroid Receptors and Coactivators research › Recipient of >30 National & International awards including Induction into the National Academy of Science & Royal Academy of Medicine Bert O’ Malley, M.D. Professor and Chairman Dept. Molecular and Cellular Biology Baylor College of Medicine
  14. 14. Spotlight: Rice Mentor › Recipient of the world's 35 Top Young Innovators by Technology Review Magazine in 2006 › Research focus on functional nanoparticle-based materials for catalytic and encapsulation/delivery applications › One of the most innovative creators of unique and useful nanomaterials Michael S. Wong, Ph.D., Assistant Professor Dept.of Chemical & Biomolecular Engineering Rice University
  15. 15. Spotlight: UTHSC-H Mentor › Nobel Prize winner in Physiology/Medicine 1998 › World leader in nitric oxide and cyclic GMP cellular signaling processes › Recipient of Numerous National & International awards/honors Ferid Murad, M.D Chair, Physiology and Medicine Director, Institute of Molecular Medicine Professor,Integrative Biology & Pharmacology UTHSC-H John S. Dunn Distinguished Chair
  16. 16. Massachusetts Institute of Technology (M.I.T.) Boston • Institute Harvard-MIT Health Science and Technology (H.S. & T.) • Department › Bioastronautics: A programme at the interface of biology, medicine, engineering and space – represents an ultimate challenge in human protection and integrative physiology › The new specialty in Medical Engineering and Medical Physics (M.E.M.P.) from the Harvard-MIT division of Health Sciences and Technology will train the bioastronautics leaders of the 21st Century • Funded By National Space Biomedical Research Institute (NSBRI) with support from NASA and Johnson Space Centre (JSC) and Private Sector • Aims To combine the biomedical and engineering disciplines of MEMP with life sciences and human factors specialisations
  17. 17. Project One: Visual Orientation, Navigation and Spatial Memory Countermeasures • Design/development of experiment investigating mismatched spatial reference frames between docked spacecraft • Development of virtual reality based oscillopsia simulator to demonstrate postlanding G excess and Otolith Tilt Translation illusions • Development of customised teleoperation training techniques tailored to individual differences in mental rotation and perspective taking skills as assessed by independent tests • Evaluation of TrackIR amplified head movement-view axis movement effects on spatial orientation and navigation in VR simulations Laboratory: Visual Orientation, Navigation and Spatial Memory Countermeasures
  18. 18. Project One: Visual Orientation, Navigation and Spatial Memory Countermeasures • Type of Students Engineering or Cognitive Psychology Students (preferably with computer graphics programming or statistical analysis) • Mentor Charles M. Oman, Ph.D., Senior Research Engineer/Senior Lecturer, Department of Aeronautics and Astronautics. Director of Man Vehicle Laboratory, M.I.T. Further Information: http://web.mit.edu/aeroastro/labs.html
  19. 19. Project Two • Title Exercise and Gravity, as achieved on a short radius (2m) centrifuge rotating at up to 1800 /sec. Measurements are made of eye movements, limb position, cardiovascular parameters and perception of orientation • Type of Student Mechanical, Aeronautical or Electrical Engineers, especially those with capability and interest in Instrumentation and Signal Processing as well as in Biomedical Engineering Applications • Mentor Lawrence R. Young, Sc.D. Apollo Programme Professor of Astronautics, Professor of Health Services and Technology, M.I.T. Laboratory: Neurovestibular Aspects of Short Radius Artificial Gravity Further Information: http://web.mit.edu/aeroastro/www/people/lry/bio.html
  20. 20. Harvard Medical School • Institute Harvard Medical School (Brigham & Womans Hospital, Boston) • Department › Division of Sleep Medicine, Developing a model Programme for Sleep and Circadian Biology › The division of Sleep Medicine is taking a leadership role in sleep medicine research, physician training and the treatment of sleep disorders. The divisions research efforts are intended to promote programmes in both basic and clinical research on issues related to sleep and circadian rhythms and further collaboration both Nationally and Internationally › The emphasis of the research and understanding of the Dept. of Sleep Medicine is on: → Sleep and Productivity: At Work, School and the Home → Sleep and Safety: At Work and on the road → Sleep and Health: diabetes, heart disease, gastrointestinal illness, hypertension, etc. • Funded By National Space Biomedical Research Institute (NSBRI) with support from NASA and Johnson Space Centre (JSC) and Private Sector • Aims The Programme of Sleep Medicine at Harvard Medical School is committed to leading in education, enabling evidence based decision making and improving the treatment of sleep disorders and other sleep related health concerns
  21. 21. Projects #1: Neurobiology of Individual Differences in Sleep Duration Mentor: Daniel Aeschbach, Ph.D., Assistant Professor of Medicine, Brigham & Women’s Hospital, Harvard Medical School #2: Sleep-Wake Actigraphy and Light Exposure During Spaceflight Mentor: Laura K. Barger, Ph.D., Research Associate in Medicine, Division of Sleep Medicine, Harvard Medical School #3: Individual Differences in Circadian Rhythms in Humans Mentor: Jeanne F. Duffy, MBA, Ph.D., Assistant Professor of Medicine (HMS), Associate Neuroscientist (BWH), Division of Sleep Medicine, Harvard Medical School #4: Comparison of Subjective and Objective Sleep Quality in Humans Mentor: Jeanne F. Duffy, MBA, Ph.D., Assistant Professor of Medicine (HMS), Associate Neuroscientist (BWH), Division of Sleep Medicine, Harvard Medical School
  22. 22. Projects #5: Effect of Light on the Human Circadian System Mentor: Steven W. Lockley, Ph.D., Assistant Professor of Medicine, Division of Sleep Medicine, Brigham and Women’s Hospital, Harvard Medical School #6: - Develop new analytic methods for sleep and circadian variables - Model the effects of different pharmacologic agents and other interventions on sleep and on waketime performance and alertness - Model hormone pulsatility Mentor: Elizabeth B Klerman M.D. Ph.D., Assistant Professor of Medicine, Division of Sleep Medicine, Brigham and Women’s Hospital, Harvard Medical School
  23. 23. Type of Students • Projects 1 - 5: Those with an interest in Physiology, Neuroscience and/or Clinical Research • Project 6: Mathematical background (at least differential equations) and programming Note: Further information on the above projects and contact details are available on request
  24. 24. Beth Israel Deaconess Medical Centre (Harvard Medical School) • Department › The Integrative Cerebral Hemodynamics Lab. is a Harvard Medical School Division of aging research centre based in Beth Israel Deaconess Medical Centre › Gerontology is the branch of Science that deals with aging and the problems of aged persons. They also examine the role of the autonomic nervous system in cerebral blood flow control during orthostatic stress • Funded By National Space Biomedical Research Institute (NSBRI) with support from NASA and Johnson Space Centre (JSC) and Private Sector
  25. 25. Beth Israel Deaconess Medical Centre (Harvard Medical School) • Aims › To focus on regulation of brain blood flow which is integral to the health of Humans. Use of an integrative approach to understand how inputs such as the vestibular and autonomic system affect cerebral blood flow regulation › Also interested in researching how affective these systems could lead to new treatment paradigms that could improve brain blood flow in aging and other conditions eg. Role of cerebral blood flow changes in the development of dementia and blood flow regulation in the pathophysiology associated with aging
  26. 26. Projects #1: Cerebral Blood Flow and Cardiac Output #2: Effect of Gravity on Functional Cerebral Blood Flow #3: Vestibular Stimulation #4: Sleep Deprivation and Blood Pressure and Cerebral Blood Flow Regulation #5: NASA sponsored 4-year Tilt Study #6: Vestibular Function Improvement
  27. 27. Projects • Mentors: All projects are supervised by: › Jorge Serrador, Ph.D., Dept. of Medicine, Gerontology › Dr Gosala S. Gopalakrishnan, Ph.D., Dept. of Integrative Cerebral Hemodynamics • Type of Students: Science, Medicine, Electrical Engineers, Clinical Research Note: Further Information on above projects is available on request
  28. 28. Florida Institute of Technology • Department › Department of Physics, Astrophysics and Space Sciences in the College of Science at Florida Institute of Technology • Previous Projects › White Dwarf Cooling Times and the Chromospheric Activity versus Age Relation for Lower Main Sequence Stars › Investigating a Yound DAO+dkb System using Photometric Time Series • Mentor Dr. T. Oswalt, Professor Physics and Space Sciences, Associate Dean of Research Further Information: http://www.fit.edu (Physics and Space Sciences)
  29. 29. Dynamac Corporation Kennedy Space Centre, Florida • Dynamac Corporation is a leading provider of research and development services to both Public and Private sector companies in the USA. Included in its major activities is R&D in the Space Life and Earth Sciences • Since 1995 Dynamac has supported nearly all Life Sciences experiments that have been launched by NASA at the Kennedy Space Centre, involving more then 80 Scientific missions and more then 150 Life Sciences experiments • Nine students nominated by U.C.C., U.C.D. and Limerick Institute of Technology have completed internships at Dynamac
  30. 30. Dynamac Corporation Kennedy Space Centre, Florida • Mentors › Garry W. Stutte, Ph.D., Senior Scientist Plant Physiology › Lanfang H Levine, Ph.D., Chemistry Lab., Manager › Neil C. Yorio, Ph.D., Phytotron Lab. Manager › Raymond M. Wheeler, Ph.D., Advanced Life Support Crop Research Land Plant Physiologist › Ray Garland, Ph.D., Senior Scientist Further Information: http://www.dynamac.com
  31. 31. Other Internship Locations • Ad Astra Technologies, Houston • Embry-Riddle Aeronautical University, Florida • Helicopters Incorporated, Florida • National Space Biomedical Research Institute (NSBRI), Houston • University of Central Florida, Florida
  32. 32. 2005 Intern Student Highlights Education: › 3 students completed Masters Degree in Ireland based on the research carried out during Internship in Houston. › 3 students currently enrolled in Ph.D. Programmes in Ireland, Scotland and US › 6 students committed to Ph.D. Programmes in next 1-2 years
  33. 33. 2005 Intern Student Highlights Oral Scientific Presentations: › All Intern students gave oral presentations at a Mini- Symposium at Baylor College of Medicine, Houston TX, March 2006 › All Intern students gave oral presentations at the closing ceremony in The Texas Medical Center, April 2006
  34. 34. 2005 Intern Student Highlights Poster Presentations: › Brita O’ Sullivan, D, Harn, M Reschke and Scott Wood. Tilt and Translation Motion Perception during Pitch Tilt with Visual Surround Translation. 7th Symposium on The Role of The Vestibular Organs in Space Exploration, 7 - 9 June 2006, ESTEC, Noordwijk, The Netherlands. › Eoghan Dillon, Christopher Crouse, and Andrew R. Barron. Polyethylenimine sidewall functionalization of fluorinated single walled carbon nanotubes . 232nd American Chemical Society Meeting & Exposition September 10 - 14, 2006, San Francisco, CA USA › Huma R. Jafry, Eoghan Dillon, Divya Chakravarthi, E. V. Barrera and Andrew R. Barron. Electrical conductance of a dispersed carbon nanotube within a polyurethane matrix . 232nd American Chemical Society Meeting & Exposition , September 10 - 14, 2006, San Francisco, CA USA › Iraida Sharina, Joanna McCarthy and Ferid Murad. Abstract accepted for poster presentation at the American Heart Association for the International Strokes Conference, San Francisco February 7-9th 2007.
  35. 35. 2005 Intern Student Highlights Manuscripts: › William Hamilton and Austin Cooney. Deciphering the role of GCNF in regulating gene expression during mammalian development. Review in preparation for submission to Frontiers in Bioscience › Brita O' Sullivan, B, D. Harm, M, Reschke and Scott Wood. Tilt and Translation Motion Perception during Pitch Tilt with Visual Surround Translation. Manuscript in preparation. (Additional publications expected at later date)
  36. 36. FÁS Science Challenge October 2006-April 2007 Interns Student Irish University Mentor US Placement Emer Lawlor DIT John Lydon Baylor College of Medicine Nicola Cahill DIT Joanne Richards Baylor College of Medicine Julie Moran DIT Janet Butel Baylor College of Medicine Carol Aherne UCD Orla Conneely Baylor College of Medicine Meabh McCurtin NUI Galway Bert O’Malley Baylor College of Medicine Nina McCarthy UCC Ferid Murad UT Medical School Jennifer Gilbert NUI Maynooth Franco DeMayo Baylor College of Medicine Edward Tierney NUI Maynooth Austin Cooney Baylor College of Medicine Gerard O’Sullivan UCC Michael Wong Rice University John Gibbons UCD Ken Whitmire Rice University Alvin Orbaek NUI Galway Andrew Barron Rice University Stuart Corr DCU Lon Wilson Rice University
  37. 37. FÁS Science Challenge October 2006-April 2007 Interns Student Irish University Mentor US Placement James Mulcahy UCD Chang Diaz Ad Astra Technologies Catherina O’Keefe LIT Garry Stutte Dynamac Corporation Karen Downing LIT Langfang Levine Dynamac Corporation Stephen O’Brien UCD Arthur Eldridge Embry-Riddle Aeronautical University Niall Graham Air Corps Patrick Corr Helicopters Incorporated Mark Hanley Air Corps Patrick Corr Helicopters Incorporated Robert Sheehan Air Corps Patrick Corr Helicopters Incorporated Barry Smyth Air Corps Patrick Corr Helicopters Incorporated Peter Raftery CityJet Arthur Eldridge Embry-Riddle Aeronautical University David Rogers CityJet Arthur Eldridge Embry-Riddle Aeronautical University

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