An introduction to brain imaging

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An introduction to brain imaging

  1. 1. functionalfunctional Brain ImagingBrain Imaging Dr John ClarksonDr John Clarkson A brief introductionA brief introduction toto
  2. 2. Computerized Axial Tomography Magnetic Resonance Imaging Quote: -the brain can look quite normal anatomically, despite the being quite marked abnormalities of function -
  3. 3. functionalfunctional Brain ImagingBrain Imaging Proton Emission Tomography Single Proton Emission Computerized Tomography functional Magnetic Resonance Imaging
  4. 4. functionalfunctional Brain ImagingBrain Imaging NuclearNuclear Medicine studies rely upon injecting substances intostudies rely upon injecting substances into the patient’s blood stream which have an affinity for thethe patient’s blood stream which have an affinity for the receptor sitesreceptor sites ((Neuro-receptorsNeuro-receptors)) contained within the cells of thecontained within the cells of the brain (brain (NeuronsNeurons).). * SPECT Scans* SPECT Scans utilize radio-active isotopes in studyingutilize radio-active isotopes in studying brain function whilebrain function while PET ScansPET Scans utilize radio-utilize radio- active labeled glucose molecules.active labeled glucose molecules. These substances are differentially taken up by the brain’s neuro-receptorThese substances are differentially taken up by the brain’s neuro-receptor sites depending on the degree of neural (neuro-transmitter) activitysites depending on the degree of neural (neuro-transmitter) activity occurring in the different regions of the brain .occurring in the different regions of the brain . SPECT ScansSPECT Scans are available and being used increasingly in Australia for theare available and being used increasingly in Australia for the investigation of neurological and psychiatric disorders.investigation of neurological and psychiatric disorders. ** functional MRI’s do not use Radioactive Isotopes;** functional MRI’s do not use Radioactive Isotopes; these investigations are very expensive and generally are onlythese investigations are very expensive and generally are only available in research institutes.available in research institutes.
  5. 5. Cerebellum Inferior-Orbital (PFC) OccipitalOccipital LobeLobe Frontal Lobe ParietalParietal LobeLobe functionalfunctional Brain Imaging -Brain Imaging - show how the brain actually works !show how the brain actually works ! Temporal Lobe
  6. 6. functionalfunctional Brain ImagingBrain Imaging SPECT SCANSSPECT SCANS [Single Photon Emission Computerized Tomography]
  7. 7. functionalfunctional Brain ImagingBrain Imaging
  8. 8. functionalfunctional Brain ImagingBrain Imaging
  9. 9. activity
  10. 10. functional Brain ImagingBrain Imaging - a m- a modern SPECT Camera
  11. 11. Brainmatters - Denver, Colorado.Consultation Room - for discussion of SPECT Scan results with patient and family
  12. 12. Neurological Disorders functional Brain ImagingBrain Imaging -- SPECT Scan ApplicationsApplications
  13. 13. Psychiatric Disorders functional Brain ImagingBrain Imaging -- SPECT Scan ApplicationsApplications
  14. 14. f Brain ImagingBrain Imaging A full introductionA full introduction toto understanding & interpreting SPECTunderstanding & interpreting SPECT is available on CD/DVD from this Web siteis available on CD/DVD from this Web site oror by attending the seminar inby attending the seminar in “A Journey through the Brain”“A Journey through the Brain” SeriesSeries The End Thank you

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