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Metalism Tracker Breezing - Educational

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An educational overview of metabolism tracking.

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Metalism Tracker Breezing - Educational

  1. 1. Breezing  Co.,  Tempe,  Arizonawww.breezing.co 1
  2. 2. The  Motivation www.breezing.co • People  spend  ~$600  billion  per  year,  yet  most  are  frustrated  with  the  results • Most  people  know  weight  management  requires  balanced  diet  and  exercise. • 2.1  billion  people,  30%  of  the  world  population,   were  overweight  or  obese  in   2013   2  out  3  Americans  are  overweight  or  Obese 2
  3. 3. The  Problem How  much   should  I  eat? How  much  should  I   exercise? www.breezing.co Why  is  my  weight   is  like  yo-­‐yo? 3
  4. 4. ~  80% ~ 10  % < 10  %  (sedentary) Total  energy  expenditure  (TEE) = -­‐ Weight Caloric  Intake + + Resting  (REE) Thermogenesis Physical  Activity Affordable  &  Mobile   Technologies Affordable  &  Mobile   Technologies The  need  …. www.breezing.co 4 (sedentary)
  5. 5. History  of  Measuring  Energy  Expenditure 1770’s Law  of  the   conservation  of   energy  à First  Human   Calorimetry Lavoisier  &   Laplace Other  Direct   Calorimetry   Efforts: Airflow,  water  flow,   water  storage,  and   gradient  layer   calorimeter 1900’s   Claude  Douglas: Gold  Standard  Indirect   Calorimetry  Method CO2 O2 + Analyzers 1890’s   Atwater  &  Rosa Wesleyan  Univ.:  First   important  work  of  Direct   Calorimetry + Analyzers 1940   Indirect  Calorimetry: Open  circuit   spirometry CO2 O2 Indirect   calorimetry: Computer-­based   Instrumentation (Breath-­by-­ breath) 1980 2000         2010 Portable  Breath-­by-­ Breath  Instrumentation CO2 O2 2014 $(10-­‐35)K 5 $350 www.breezing.co First  Mobile   Metabolism   Tracker
  6. 6. ~  80% ~ 10  % < 10  %  (sedentary) Total  energy  expenditure  (TEE) = -­‐ Weight Caloric  Intake + + Resting  (REE) Thermogenesis Physical  Activity Affordable  &  Mobile   Technologies Affordable  &  Mobile   Technologies The  need  …. www.breezing.co 6 (sedentary)
  7. 7. Resting Energy Expenditure (REE) Resting Metabolic Rate (RMR) Food  + Oxygen Carbon   Dioxide +  ATP  (heat),  storage O2 CO2 Resting  Metabolism: ✓ Sustains  life ✓ Majority  of  our  daily  total  energy   expenditure • VO2 consumed   oxygen  rate   • VCO2 produced  carbon   dioxide  rate 7 How  does  it  work? •Indirect  calorimetry  (Breezing  measures   consumed  oxygen  rate  and  produced   carbon  dioxide  rate) •Recommended  by  AND,  WHO,  ACSM,   ADA www.breezing.co
  8. 8. Energy  management:  Cardio-­‐Pulmonary  System • VO2 consumed  oxygen  rate   • VCO2 produced  carbon  dioxide  rate Right  Side   of  Heart Lungs CaO2  -­ CvO2 =  5  mL  O2  per  100  mL CO2 CO2 CO2 O2 O2 O2 O2 Muscle  and Tissues Left  Side   of  Heart Energy  (ATP) 8 www.breezing.co
  9. 9. Indirect  Calorimetry  Principle Weir,  J.  B.  D.  (1949).  "New  Methods  For  Calculating   Metabolic  Rate  With  Special  Reference  To  Protein  Metabolism."  Journal  Of   Physiology-­London  109(1-­2):  1-­9. Weir,  J.  B.  D.  (1990).  "Nutrition  Metabolism  Classic  -­ New  Methods  For  Calculating   Metabolic-­Rate  With  Special  Reference  To  Protein-­ Metabolism."  Nutrition  6(3):  213-­221. REE  (kCal/day)  =  [3.9  (VO2)  +  1.1  (VCO2)]  x  1.44 VO2:  consumed  oxygen  rate  (mL/min) VCO2:  produced  carbon  dioxide  rate  (mL/min) Weir  Equation: Resting  Energy  Expenditure: 9 www.breezing.co
  10. 10. Direct  Calorimetry  vs.  Indirect  Calorimetry Indirect  Heat   Measurement CO2 O2 Direct  Heat   Measurement 10 www.breezing.co
  11. 11. Direct  Calorimetry  vs.  Indirect  Calorimetry Direct  Heat   Measurement Indirect  Heat   Measurement CO2 O2 2717  kCal/day   2723  kCal/day   1900  -­‐ Atwater  &  Rosa’   research:   Energy  expenditure   of  3   men  who  lived  in  the   calorimeter  for  40  days Error:  +/-­‐ 0.2  %   *  Other  researchers’  experiments:  Error  =  +/-­‐ 1% 11 Science  demonstrated  that  direct  calorimetry  is  equivalent  to  indirect  calorimetry
  12. 12. Oxygen Carbon Dioxide Oxygen Carbon Dioxide 1700  kCal/day 1200  kCal/day Your  metabolism  =   Your  energy   =  Your  Fire Why  track  metabolism? Weight:  112  lbs Height:  5’  6’’ Age:  29  years 12 www.breezing.co Different  people  have   different   metabolisms
  13. 13. ExerciseGenetics   Diet Drugs,  substances   Pregnancy Informacion  from  Sport  Nutrition  for  Health  and  Performance,  M.  Manore,  N.  Mayer,  J.  Thompson  -­‐ 2009 Hormones 13 www.breezing.co Why  track  metabolism? Different  factors  can   affect  metabolism
  14. 14. 14 www.breezing.co Tracking  Metabolism  for  Better  Health Diet Changes  in  diet  can  significantly  change  metabolism.  For   example,  a  crash  diet  can  cause  drastic  reduction  in   metabolic  rate,  leading  to  a  “weight  loss  plateau”.  See   slides  23-­‐24,  and  “Case  Studies”  Case  #8. Exercise Exercise  can  affect  metabolism. For  example,  muscle-­‐ building  increases  metabolism  and  High  Intensity   Intermittent  Training  (HIIT)  creates  an  “afterburn”  effect. See  slides  27-­‐28,  and  “Case  Studies”  Cases #6  and #7. Hormones/medication Hormonal  changes  and  medications  can  change   metabolism.  Monitoring  metabolism  helps  screen  for   potential    hyper-­‐ or  hypo-­‐thyroidism.  See  “Case   Studies” Case  #5. Pregnancy Metabolism changes  significantly throughout  pregnancy   and  after  giving  birth.  Tracking  metabolism  helps  the   mother  maintain  and  achieve  the  proper  weight  for  the   baby’s  healthy  growth.  See  “Case  Studies”  Case  #3.
  15. 15. GJODMS,  March,  2015 Tracker  for  Resting  Energy  Expenditure  (REE)  or   Resting  Metabolic  Rate 15
  16. 16. GJODMS,  March,  2015 The  Tracker  for   Energy  Expenditure   (EE)  demonstrated   ~100%  accuracy 16
  17. 17. 17 Moscow  Hospital  -­‐ 2014 Link  a  video:  hUps://yadi.sk/i/AS_kZZKddY3DA Other  independent  validations  (case  #1) www.breezing.co Professionals in Moscow’s Hospital have probed that Breezing functions at the same level of expensive metabolic carts (100 times more expensive than Breezing)
  18. 18. 18 Grupo  GAYTA/COINCIDE group,   México  -­‐ 2014 Other  independent  validations  (case  #2) www.breezing.co Atlas soccer team’s Sports Nutrition Team (COINCIDE) has demonstrated the importance of measuring metabolism in Sports Nutrition
  19. 19. Other  independent  validations  (case  #3) 19 Comparison  with  Fitmate  (Cosmed)  -­‐ 2014 Difference  between  Breezing  and  Fitmate  of  4  kCal/daywww.breezing.co
  20. 20. 20 Other  groups/institutions  using  Breezing British   Columbia Vincennes University www.breezing.co
  21. 21. Importance  of  Metabolism  for  Weight  Management Resting  Metabolic  Rate  (RMR)  =  “Metabolism”  =  Resting  Energy  Expenditure  (REE) 21 www.breezing.co
  22. 22. Food Total  Energy  Expenditure  (TEE)  =   Calories  burned Calorie Intake PA REE Physical  Activity Metabolism   (>75%) Energy  Balance  and  Weight  Loss     Food-­‐induced  Thermogenesis 22 www.breezing.co
  23. 23. Weight Target  Weight 1 Weight  maintenance 1 2 Weight    loss1 2 3 REE  Drop  =   No  weight  loss2 Time 3 1-­‐ Seagle,  H.  M.,  G.  W.  Strain,  et  al.  (2009).  "Position   of  the  America  Dietetic   Association:  Weight  Management."  Journal  Of  The  American  Dietetic   Association  109(2):   330-­‐346. 2  -­‐ Elliot,   D.  L.,  L.  Goldberg,   et  al.  (1989).  "SUSTAINED  DEPRESSION  OF  THE  RESTING  METABOLIC-­‐RATE  AFTER  MASSIVE  WEIGHT-­‐LOSS."  American  Journal  Of  Clinical   Nutrition   49(1):  93-­‐96. -­‐ Heshka,  S.,  M.  U.  Yang,  et  al.  (1990).  "WEIGHT-­‐LOSS  AND  CHANGE  IN  RESTING  METABOLIC-­‐RATE."  American  Journal   Of  Clinical  Nutrition   52(6):  981-­‐986. -­‐ Leibel,   R.  L.,  M.  Rosenbaum,  et  al.  (1995).  "CHANGES  IN  ENERGY-­‐EXPENDITURE   RESULTING  FROM  ALTERED  BODY-­‐WEIGHT."  New  England  Journal  of  Medicine   332(10):  621-­‐628. Unsustainable  Weight  Loss  Problem 23 Metabolism  can  drop  ! www.breezing.co
  24. 24. 1 2 Weight  maintenance Weight    loss Weight Time Target  Weight 1 2 3’ 3’ REE  Increase  =   Weight  loss Sustainable  Weight  Loss Monitoring  Resting   Energy  Expenditure 24 www.breezing.co
  25. 25. 1 2 3 4 5 6 0 20 40 60 80 100 Mean:  85.1% Standard  Deviation:  2.9% REE  /  TEE  (%) Subject  (#) Most  of  daily  total  energy  expenditure  (TEE)  is   spent  to  maintain  basic  body  functions (energy  expenditure  at  resting  state,  EER  or  REE) How  Sedentary  Are  We? Total  Energy  Expenditure* Resting  Energy  Expenditure  (REE) Thermogenesis Physical  Activity 75  % 15  % ~10  % *McArdle,  Katch &  Katch,  Ex.  Physiology,   2009   1 2 3 4 5 6 7 0 4 8 12 16 20 24 Driving Bench  Work Watching  TV Walking Office  Work Sleeping Daily  Activity  (hs) Subject  (#) Leisure Lab  Work Work  from  Arizona  State  University,  2013
  26. 26. 1 2 3 4 5 6 0 20 40 60 80 100 Mean:  85.1% Standard  Deviation:  2.9% REE  /  TEE  (%) Subject  (#) 1 2 3 4 5 6 7 0 4 8 12 16 20 24 Driving Bench  Work Watching  TV Walking Office  Work Sleeping Daily  Activity  (hs) Subject  (#) Leisure Most  of  daily  total  energy  expenditure  (TEE)  is   spent  to  maintain  basic  body  functions (energy  expenditure  at  resting  state,  REE) How  Sedentary  Are  We? Total  Energy  Expenditure* Resting  Energy  Expenditure  (REE) Thermogenesis Physical  Activity >  80  % <  5  %~10  % *Exercise  Physiology,   McArdle,  Katch &  Katch 15%  à 5% 75%  à >80% Work  from  Arizona  State  University,  2013
  27. 27. Food Total  Energy  Expenditure  (TEE)  =   Calories  burned Calorie Intake PA REE Physical  Activity   Metabolism   (>75%) (80-­‐90  %  in   sedentary   persons) Energy  Balance  – How  we  can  modify  it? Food-­‐induced  Thermogenesis 27 www.breezing.co
  28. 28. Total  Energy  Expenditure  (TEE) P A REE Physical  Activity Metabolism Food-­‐induced  Thermogenesis 28 Metabolism  (RMR)  and  Physical  Activity* P A REE Exercise P A REE *Speakman et.al.,  Proceeding  of  the  nutrition  society,  2003,  62,  621-­‐634  (Fig.2  reproduction) Total Effect  of Sustained Exercise www.breezing.co
  29. 29. How  we  can  increase  metabolism  and  reverse  sedentary   lifestyles  without  drastically  altering  our  schedules? 29 High  Intensity  Intermittent  Training  (HIIT) Work  from  Arizona  State  University,  2013 www.breezing.co
  30. 30. Jessica and Andrew Troy, Personal Trainer Gabriel Olympic Diver, Mexico Fang, pregnant mom (episode 1, episode II) Dr. Sabagh Real  User  Stories

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