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Enfermedad Mano pie boca

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Enfermedad mano, pie boca

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Enfermedad Mano pie boca

  1. 1. ENFERMEDAD MANO PIE BOCA
  2. 2. DEFINICIÓN • ESTOMATITIS VESICULAR CON EXANTEMA • Infección sistémica producida por – Coxackievirus A16, A4 -7, A9, A10, B2 y B5 – Enterovirus 71;
  3. 3. • Caracterizada por lesiones bucales ulceradas y exantema vesicular en la parte distal de extremidades; • Asociado con síntomas generales de grado leve.
  4. 4. ETIOLOGIA • Virus ARN sin capa lipídica • Perteneciente a la familia Picornaviridae • Género Enterovirus. * Se dividen en dos grupos:  A: 23 serotipos A16 Infectan piel y mucosas  B: 6 serotipos Infectan corazón, pleura, páncreas e hígado
  5. 5. EPIDEMIOLOGIA • Mayor frecuencia en niños menores de 10 años y adultos jóvenes Brotes epidémicos en meses de más calor • Clima tropical • Verano u otoño • Muy contagiosa • Transmisión persona a persona • Si existe brote en una comunidad, el riesgo de infección se acentúa en lactantes y niños menores de 5 años.
  6. 6. MECANISMO DE TRANSMISION  Persona a Persona (flugge)  Contacto directo con manos sucias o superficies contaminadas con heces.  Es posible que se trasmitan a través de objetos contaminados de los enfermos. PERIODO DE INCUBACION 3 a 7 días
  7. 7. PATOGENIA • Transmisión vía Flugge ó fecal:oral – Implantación virus en Tracto GI o Tracto respiratorio • (mucosa bucal e íleon) – Diseminación Ganglios Linf.regionales – Viremia – Diseminación mucosa bucal, piel de manos y pies
  8. 8. CUADRO CLÍNICO • INCUBACIÓN: 3-6 días • PRÓDROMOS (12-24 hrs.): febrícula, malestar general., dolor abdominal y síntomas respiratorios. • Periodo Clínico • Vesículas en mucosa oral • 3 y 7 mm pared delgada tipo ulcerativa con un halo eritematoso, ovales o lineales pero no circulares
  9. 9. CUADRO CLÍNICO • PIEL: (palmas y plantas, dedos, gluteos) • Máculas o pápulas rosadas o rojas, de 2-8mm, múltiples, con configuración “Lineal” • Evolucionan a vesículas (líq. claro o amarillento) • Formación de erosiones y costras • Asintomáticas o dolorosas, no producen prurito • Curan sin cicatrización • Síntomas asociados: eritema faríngeo, fiebre, malestar gral., diarrea, dolor articular, raro sintomatología Neurológica.
  10. 10. CUADRO CLÍNICO
  11. 11. DIAGNOSTICO • Anamnesis • Examen Físico *Detección del virus en el líquido de la ampolla por reacción en cadena de la polimerasa (PCR). Puede detectar enterovirus con una sensibilidad de aproximadamente el 90 por ciento, que no permite la identificación del serotipo. • Coxsackievirus A16 secuenciación de nucleótidos se puede realizar en muestras positivas de PCR para confirmar el diagnóstico
  12. 12. DX DIFERENCIAL • Mononucleosis infecciosa • Herpesvirus • Estomatitis aftosa • Herpangina • Eritema multiforme grave
  13. 13. DIAGNOSTICO DIFERENCIAL HERPANGINA Úlceras pequeñas de 2 a 4 mm. de diámetro localizadas en paladar blando y pilares amigdalianos GINGIVOESTOMATITIS HERPETICA Lesiones en toda la mucosa oral incluyendo la encía adherida y en forma de roseta ESCABIOSIS Vesículas en manos, pliegues y pies pruriginosas de color violaceo
  14. 14. COMPLICACIONES • Meningitis aséptica • Encefalitis • Parálisis tipo polio • Convulsiones • Deshidratación severa
  15. 15. TRATAMIENTO • El tratamiento indicado es solamente el alivio sintomático • La fiebre y el dolor : acetaminofeno • Ingesta de líquidos (pérdida de líquidos corporales).
  16. 16. PREVENCION • Lavarse las manos frecuentemente con agua tibia y jabón: -Antes de preparar los alimentos y de comer y - Después de cambiar un pañal • Desinfectar las superficies contaminadas • El no tener contacto íntimo con las personas infectadas también podría ayudar a reducir el riesgo de infección. (No besarse, abrazarse, compartir utensilios, etc.)

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