chicken pox

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chicken pox

  1. 1. Chickenpox (VARICELLA) Dr. BOUNIKA ESVANTH RAO, Dr. JERUBA JAYAKUMAR, Dr. NEELAVENI MARIMUTHU SAMY, Dr. PRIYADHARSHINI JOTHI MURUGAN.
  2. 2. ETIOLOGIC AGENT  Caused by varicella zoster virus related to Herpes simplex virus Cytomagalo virus Epstein bar virus (EBV)  Primary infection results in Varicella.  Recurrent infection results in herpes zoster (shingles).  Source : &
  3. 3. INCUBATION PERIOD  10- 21 days. SPREAD OF DISEASE & INFECTIOUS PERIOD  One two days before the appearance of the rash and lasts till all the lesions have crusted (5-7 days).
  4. 4. CLINICAL PICTURE  Stage of invasion / prodromal stage.  Stage of eruption.  Convalescence
  5. 5. STAGE OF INVATION (2-3 days)  Symptoms  Before the appearance of the skin rash enantham develops
  6. 6. STAGES OF ERUPTION  Progress of lesion Macular Papular Vesicular Pustular
  7. 7. CONVALECENCE •Rashes lasts for 3-4 days. •Formation of scabs. •Superficial scars.  Complete clearance of skin may take few days.
  8. 8. VARITIES OF CHECKEN POX  Varicella bulla: characterized by formation of bullous eruptions.  Varicella ganrenosa: It is seen in ill- nourished children and there are dark crusts are formed in the eruptions which on separation leave behind ulcers.  Varicella haemorrhagica: Uncommon virulent form of varecella . Hemorrhages occur into the vesicles and bleeding may take place from the mucous membrane.
  9. 9. COMPLICATIONS  RESPIRATORY:  Laryngitis, Bronchitis, Bronchopneumonia.  SKIN:  Erysipelas, Cellulitis, Impetigo.  RENAL:  Nephritis .  SYSTEMIC:  Arthritis, Myocarditis, Purpura, Encephalomylitis.
  10. 10. SEVERE IN
  11. 11. DIAGNOSIS  Classical appearance of rash.  Aspiration of vesicular fluid.  PCR tissue culture.  Serological examination for rising titers of antibodies is only useful in primary infection.  Staining of scrapings in with fluorescein labeled monoclonal antibody.
  12. 12. TREATMENT Use of antivirals Indications: For those patients for whom VZIG is not indicated Dose: Oral acyclovir 40mg/kg/day in 4 divided doses given from days 7 to 14 after exposure (Kumagai et al, 1999)
  13. 13. PROPHYLAXIS Dosage and Timing of VZIG (to be given within 10 days of exposure). 0 – 5 Years 250mg by 6 – 10 Years 500mg slow 11 – 14 Years 750mg intramuscular 15 years and older 1000mg injection PASSIVE IMMUNISATION LIVE ATTENUATED VARICELLA VACCINE (VARIVAX) In a dose of 0.5 ml is administered in all children above the age of 21 months for immunization. A booster dose after 6 years of vaccination is given in some children.
  14. 14. PROGNOSIS A case of chicken pox has a self limiting course and in an uncomplicated case prognosis is good.
  15. 15. ANY QUESTIONS?

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