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Hemmerich bosc2010 isga_ergatis


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Hemmerich bosc2010 isga_ergatis

  1. 1. AUTOMATED  ANNOTATION  OF   NGS  TRANSCRIPTOME  DATA   USING  ISGA  AND  ERGATIS Chris Hemmerich Center for Genomics and Bioinformatics Indiana University, Bloomington, Indiana
  2. 2. Keeping up with next-generation sequencing data requires the use of automated analysis pipelines!
  3. 3. Ergatis is a(n awesome) workflow management tool for designing and running such pipelines!! Ergatis: A web interface and scalable software system for bioinformatics workflows! Orvis et al. (2010) Bioinformatics !
  4. 4. ISGA is a Biologistʼs tool for running and customizing Ergatis pipelines previously designed by experts!! An Ergatis-based prokaryotic genome annotation web server! Chris Hemmerich, Aaron Buechlein, Ram Podicheti, Kashi Revanna & Qunfeng Dong, (2010) Bioinformatics!
  5. 5. INTEGRATIVE SERVICES FOR GENOMIC ANALYSIS   Account system protects user data and enables easy retrieval of previous results   Integrated visualization, query, and analysis tools to explore pipeline results   File upload and download managed through browser   ISGA pipelines can be run in Ergatis
  6. 6. TRANSCRIPTOME PIPELINE !"#$%&"'()*+,-.,/0,$&,- .,/0,$&,-60#2')7-8'2),"- 9?@.!<- 9?@.!<- 9?@.!A- <=9>-$"- 12'3*4'&5,"- IJK.!- .,2L- 9?@.!4- 4H1.>!K-.=@<- 1H84",I'&)*"- 92#%):;1- !9?@.!<- !#D*$*+7- 1")M*F=?NO9- EF,3#$G- ?'(*4B-.'3$#24-C-!#"3,)4- H,L,",$&,- ;,$*+,- 1")M*F=?-
  7. 7. Transcriptome pipeline is running in Ergatis. We are optimizing performance and evaluating additional functionality.!!
  8. 8. CREDITS Qunfeng Aaron Ram Kashi Jeong-Hyeon Dong Buechlein Podicheti Revanna Choi Haixu Tang