About Swine flu.
Causes of swine flu.
About the drug.
Prevention & precaution’s.
1) What is swine flu…?
Swine flu is a disease which caused by orthomyxovirus.
Swine flu is an acute and highly spreading by contact
Swine flu is also called as hog flu (or) pig flu.
Now a days the swine influenza A [H1N1] virus that
has infected in human.
Normally this virus is resistant to the antiviral drugs &
also resistant to vaccine.
1920 1940 1960 1980 2000
1918: “Spanish Flu” 1957: “Asian Flu” 1968: “Hong Kong Flu”
20-40 million deaths 1-4 million deaths
1-4 million deaths
Swine influenza is known to be caused by influenza A
subtypes they are… 1) H1N1,
Reassortment in pigs
How it is caused and when…?
Reassortment in birds
H1N1 is spread primarily through contact with an infected
person like the common flu.
Routes of transmission are mainly through coughing or
sneezing. Also, the virus can survive on contaminated
surfaces for up to 2 hours.
What are the Symptoms of Swine
aCCording to the CdC, like seasonal flu, symptoms
of swine flu infeCtions Can inClude:
Runny nose or stuffy nose.
Serious Symptoms of Swine
Acute respiratory distress.
Bluish or gray skin color.
Inflammation of the brain &heart.
Relenza [Zanamivir], Tami flu [Oseltamivir], amantidine
(symmetrel), rimantadine (Flumadine) are currently one
of the most powerful drugs against the Swine flu virus.
Treatment by 2 types.
About the drug…,
GENERIC NAME : zanamivir
BRAND NAME : Relenza
DRUG CLASS AND MECHANISM :
Zanamivir is a neuraminidase inhibitor.
That prevents the spread of influenza A and B
The viruses responsible for the "flu."
Neuraminidase is an enzyme that is required by
the influenza viruses to spread from infected
cells to healthy cells
Zanamivir blocks the action of neuraminidase
there by reducing the spread of influenza. Since
the spread of the viruses is prevented,
The symptoms and duration of infection are
STORAGE: Store at room temperature,
PREGNANCY:Zanamivir has not been
adequately evaluated in pregnant women.
The most frequent side effects are
Ear, nose and throat infections may occur.
Patients who have asthma or other breathing problems
do not use this drug.
Zanamivir is administered by oral inhalation.
The recommended dose is two inhalations
(5 mg per inhalation) twice daily for five days.
• No vaccine available to protect humans from
• Vaccine for human seasonal influenza does not
protect against H1N1 swine flu viruses due to
antigenic differences, but may provide partial
protection against swine H3N2 virus
Preventive & Precautions measures
of swine flu…?
If hot water is not available, use an alcohol-based
Wash your hands frequently with soap & hot running
Get a regular seasonal flu vaccination.
Avoiding contact with ill persons.
Staying at home if you are sick, to avoid affecting
Be aWare OF sWine FLu (Pig FLu).......
For the most current information on the H1N1 influenza
outbreak, visit http://www.cdc.gov/h1n1flu/
International Committee on Taxonomy of Viruses. "The
Universal Virus Database, version 4: Influenza A".
a b c d e f "Swine influenza". The Merck Veterinary Manual.
. Retrieved on April 30, 2009.
V Trifonov, H Khiabanian, B Greenbaum, R Rabadan (30
April 2009). "
The origin of the recent swine influenza A(H1N1) virus infectin
". Eurosurveillance 4 (17).
Maria Zampaglione (April 29, 2009). "Press Release:
A/H1N1 influenza like human illness in Mexico and the USA:
OIE statement". World Organisation for Animal Health.
http://www.oie.int/eng/press/en_090427.htm. Retrieved on
April 29, 2009.
Swine influenza World Health Organization 27 April 2009
"Influenza A(H1N1) frequently asked questions". WHO.int.
Retrieved on 2009-05-07.