Schizophrenia A Connection to Genetics
Is Schizophrenia Genetic? <ul><li>Not entirely: there are certain genes that contribute, but onset depends on the environm...
Can Schizophrenia Be Inherited? <ul><li>No, not specifically. There is one gene linked to the disorder; however, little he...
Symptoms <ul><li>There are three types of symptoms: positive, negative, and cognitive. </li></ul><ul><li>Positive symptoms...
Prognosis <ul><li>There are many factors that determine a good prognosis or a bad prognosis </li></ul><ul><li>Factors for ...
Prognosis <ul><li>Factors for a poor prognosis: early onset, being male, more negative symptoms, a family history of schiz...
Incidence <ul><li>Schizophrenia occurs in about 7.2 out of 1000 people in the United States alone, about twice as many as ...
Treatments <ul><li>Treatment of schizophrenia today are limited to symptom-treating medicines and certain therapies, thoug...
Treatments <ul><li>There are various therapies in existence to treat schizophrenia, which are used as supplements to medic...
Bibliography <ul><li>Schizophrenia.com.  Heredity and the Genetics of Schizophrenia.  Retrieved from  < http://schizophren...
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Schizophrenia and Genetics

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Schizophrenia and Genetics

  1. 1. Schizophrenia A Connection to Genetics
  2. 2. Is Schizophrenia Genetic? <ul><li>Not entirely: there are certain genes that contribute, but onset depends on the environment around the individual. </li></ul><ul><li>The only gene strongly connected to schizophrenia is a gene on chromosome 22 named COMT. When abnormal, COMT depletes the frontal lobes in the brain of the neurochemical dopamine, causing hallucinations and an impaired sense of reality, both symptoms of schizophrenia. </li></ul>
  3. 3. Can Schizophrenia Be Inherited? <ul><li>No, not specifically. There is one gene linked to the disorder; however, little heredity is found in schizophrenia. The highest instance of there being two cases of schizophrenia in a family is between twins, and the instance of that is less than 50%, suggesting that schizophrenia is not inherited. Again, it depends on the environment around the individual. </li></ul>
  4. 4. Symptoms <ul><li>There are three types of symptoms: positive, negative, and cognitive. </li></ul><ul><li>Positive symptoms include: hallucinations (visual and auditory), delusions, and racing thoughts. </li></ul><ul><li>Negative symptoms include: apathy, lack of emotion, and poor social functioning. </li></ul><ul><li>Cognitive symptoms include: disorganized thoughts, difficulty concentrating or completing tasks, and memory problems. </li></ul>
  5. 5. Prognosis <ul><li>There are many factors that determine a good prognosis or a bad prognosis </li></ul><ul><li>Factors for a good prognosis: a diagnosis of paranoid schizophrenia (easier to treat with medicine), being female (respond better to treatment), fewer negative symptoms, a later onset, a good support system, and a shorter period of active symptoms (a mania, e.g.). </li></ul>
  6. 6. Prognosis <ul><li>Factors for a poor prognosis: early onset, being male, more negative symptoms, a family history of schizophrenia, a poor support system, and substance abuse. </li></ul><ul><li>Many with schizophrenia do manage to live productive lives despite the disorder, though some with it are institutionalized. </li></ul>
  7. 7. Incidence <ul><li>Schizophrenia occurs in about 7.2 out of 1000 people in the United States alone, about twice as many as Alzheimer’s. </li></ul><ul><li>Worldwide, schizophrenia occurs in about 1.1% of the population over 18 years of age. From country to country, the rate varies from .5% to 1% of the country's population. </li></ul>
  8. 8. Treatments <ul><li>Treatment of schizophrenia today are limited to symptom-treating medicines and certain therapies, though disease-treating medicines are in the making. </li></ul><ul><li>Most people with schizophrenia take multiple medicines. There are medicines to partially control positive symptoms, and there are antipsychotics to treat the negative and cognitive symptoms. </li></ul>
  9. 9. Treatments <ul><li>There are various therapies in existence to treat schizophrenia, which are used as supplements to medications. These include psychological and cognitive therapies. </li></ul><ul><li>Some patients also respond well to electroconvulsive therapy or transcranial magnetic stimulation, both of which are controversial but effective and safe. </li></ul>
  10. 10. Bibliography <ul><li>Schizophrenia.com. Heredity and the Genetics of Schizophrenia. Retrieved from < http://schizophrenia.com/research/hereditygen.htm >. May 21, 2011. </li></ul><ul><li>Schizophrenia.com. Schizophrenia Symptoms. Retrieved from < http://www.schizophrenia.com/diag.php >. May 21, 2011. </li></ul><ul><li>Schizophrenic.com. Schizophrenia Prognosis. Retrieved from <http://www.schizophrenic.com/content/schizophrenia/diagnosis/ schizophrenia-prognosis>. May 21, 2011. </li></ul><ul><li>Schizophrenia.com. Schizophrenia Facts and Statistics. Retrieved from < http://schizophrenia.com/szfacts.htm >. May 21, 2011. </li></ul><ul><li>Schizophrenia.com. Schizophrenia Treatment. Retrieved from < http://schizophrenia.com/sztreat.html >. May 21, 2011. </li></ul>

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