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Bioinformatics Projects And Applications

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Introduction to bioinformatics and applications

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Bioinformatics Projects And Applications

  1. 1. Bioinformatics Projects and Applications Paulsharma Chakravarthy [email_address]
  2. 2. Approaches <ul><li>Design and implementation of new algorithms and statistics which assess relationship among members of large data sets. </li></ul><ul><li>Analysis and interpretation of various data types, which includes nucleotide and amino acid sequences and structure of protein. </li></ul><ul><li>To develop computational tools and databases that enables efficient analysis, access and management of biologically significant information. </li></ul>
  3. 3. Bioinformatics Tools <ul><li>Sequence Analysis </li></ul><ul><li>Structure Visualization </li></ul><ul><li>Structural Analysis </li></ul><ul><li>Molecular Simulation and Dynamics </li></ul><ul><li>Molecular Docking </li></ul><ul><li>Cheminformatics Tools </li></ul><ul><li>Data Mining Tools </li></ul>
  4. 4. Various Specialized Application <ul><li>Gene Prediction </li></ul><ul><li>Genome Annotation </li></ul><ul><li>Structure Prediction </li></ul><ul><li>Expression Analysis </li></ul><ul><li>Drug Discovery </li></ul><ul><li>Compound Screening </li></ul>
  5. 5. Research Projects <ul><li>Analyzing raw experiment data </li></ul><ul><li>Gene Prediction and Genome Annotation </li></ul><ul><li>Sequence Analysis of unique genes </li></ul><ul><li>Codon Usage Analysis </li></ul><ul><li>Analyzing Microarray expression data </li></ul>
  6. 6. <ul><li>Phylogenetics </li></ul><ul><li>Protein Folding and Structural Analysis </li></ul><ul><li>Structure prediction and Molecular Modeling </li></ul><ul><li>Molecular Docking </li></ul><ul><li>Development of Secondary structure Algorithm </li></ul>
  7. 7. <ul><li>Drug discovery </li></ul><ul><li>Identification of Drug Targets </li></ul><ul><li>Designing a Bioinformatics Software </li></ul><ul><li>Designing a Bioinformatics database </li></ul><ul><li>Comparative Genomics </li></ul><ul><li>Cancer Genomics </li></ul><ul><li>Metabolic pathway analysis </li></ul><ul><li>Metabolic pathway mapping </li></ul>
  8. 8. <ul><li>Cheminformatics </li></ul><ul><li>Molecule screening for drug discovery </li></ul><ul><li>In silico Drug Likeness </li></ul><ul><li>In silico ADMET </li></ul><ul><li>Molecular simulation </li></ul><ul><li>Web based Applications / web datasets </li></ul>
  9. 9. Project Steps <ul><li>Identify a relevant problem </li></ul><ul><li>Define the problem </li></ul><ul><li>Literature Review </li></ul><ul><li>Objective to find solution for the chosen problem </li></ul><ul><li>Methods </li></ul><ul><li>Results expected </li></ul><ul><li>Analysis </li></ul><ul><li>Interpretation </li></ul><ul><li>Documentation </li></ul>

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