Tumor markers ppt BIOCHEMISTRY

5,015 views

Published on

Published in: Health & Medicine
0 Comments
6 Likes
Statistics
Notes
  • Be the first to comment

No Downloads
Views
Total views
5,015
On SlideShare
0
From Embeds
0
Number of Embeds
5
Actions
Shares
0
Downloads
490
Comments
0
Likes
6
Embeds 0
No embeds

No notes for slide

Tumor markers ppt BIOCHEMISTRY

  1. 1. Definition Clinical uses Classification Examples
  2. 2. Substance found in increased amounts in the blood, other body fluids and tissues that may suggest the presence of cancer Definition
  3. 3. Diagnosis Prognosis Monitor treatment Detection of recurrence Screening
  4. 4. Hormones Oncofetal Antigens Enzymes Tumor- Associated Proteins
  5. 5. Human chorionic gonadotropin • Gestational trophoblastic disease • Gonadal germ cell tumor Calcitonin • Medullary cancer of the thyroid Catecholamines • Pheochromocytoma
  6. 6. Oncofetal antigens • Hepatocellular carcinoma, • Gonadal germ cell tumor α-Fetoprotein • Adenocarcinomas of the colon, pancreas, lung, breast, ovary Carcinoembryonic antigen
  7. 7. • Prostate cancer Prostatic acid phosphatase • Small cell cancer of the lung, • Neuroblastoma Neuron-specific enolase • Lymphoma, • Ewing's sarcoma Lactate dehydrogenase
  8. 8. Tumor-Associated Proteins Prostate- specific antigen Prostate cancer Monoclonal immunoglobulin Myeloma CA-125 Ovarian cancer CA19-9 Colon, pancreatic, breast cancer
  9. 9. The crucial link between anatomy and molecular pathways From anatomy… via serological tumor markers … to molecular pathways Lung KIT Breast EGF R Prostate HER 2 Colon BRAF

×