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"Successful model of public and private collaboration: MaRS", ZAYNA KHAYAT

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"Successful model of public and private collaboration: MaRS", ZAYNA KHAYAT

  1. 1. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Visit us at marsdd.com Successful models of public and private collaboration N O V E M B E R 2 5 , 2 0 1 6 Zayna Khayat, Ph.D. Health System Innovation MaRS Discovery District zkhayat@marsdd.com @ZaynaKhayat | @MaRSDD
  2. 2. British Columbia (5 million)  PHIX  Innovation Boulevard  Minister Davidson  IHSTS Alberta (4 million)  Strategic Clinical Networks  TEC Edmonton Ontario (14 million people, $50B health spend)  Office of Chief Innovation Strategist  First Nations health  MaRS EXCITE Quebec (8 million people)  Rx policy  Aggressive reforms Health policy meets industrial policy 2Zayna Khayat – MaRS Discovery District (2016) Canada • 35 million people • $220B health spending
  3. 3. Ontario: the first province to have a Chief Innovation Officer for healthcare Mandate: use the $50B health system to drive the new health economy To read the full report visit www.ohic..ca 3
  4. 4. 10% 25% 9% 52% 4% BOSTON REGION Employment: 82,000 19% 12% 8% 55% 6% SAN FRANCISCO REGION Employment: 63,000 9% 15% 10% 59% 7% SAN DIEGO REGION Employment: 62,000 The Toronto region health cluster 4 Source: Jones, Lang, LaSalle. Life Sciences Cluster Report 2014 Toronto region aiming to be a top 5 human health science clusters. 27% 15% 14% 31% 13% TORONTO REGION Pharma & medicine manufacturing Electromedical instrument manufacturing Medical equipment & supplies manufacturing Testing Labs and R&D Medical & diagnostic laboratories Employment: 38,000
  5. 5. Developingtalent•Growingventures•Openingmarkets Visit us at marsdd.com November 2016 MaRS works with partners to catalyze, accelerate, scale and diffuse innovation. We help entrepreneurs start and grow successful global companies. Together, we help Canada prosper. Our Future Matters. Build the new economy. Improve society. Health | Energy & Environment | Finance & Commerce | Work & Learning
  6. 6. Developingtalent•Growingventures•Openingmarkets Our Future Matters November 2016
  7. 7. Developingtalent•Growingventures•Openingmarkets Visit us at marsdd.com Dense biocluster + biz + gov + arts February 2016
  8. 8. Developingtalent•Growingventures•Openingmarkets Our Future Matters MaRS: North America’s largest urban innovation hub February 2016 MaRS Centre •1.5 million square feet •200+ organizations, ~6,000 people •Science, business (startups to multinationals), investors, enablers •Co-location, incubation, collaboration, resources and local/global networks
  9. 9. Developingtalent•Growingventures•Openingmarkets Visit us at marsdd.com Private Public/para-public Coming in 2016: Starbucks, Facebook Canada headquarters and J&J’s largest global JLABS Accelerator. University of Toronto Asset Management Sample Tenants Examples of MaRS Centre Tenants November
  10. 10. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters • 40,000 square feet @ MaRS • 50-70 health startups incubated • Rx + med tech + digital health + consumer • Access to J&J global networks • No strings attached model 10Zayna Khayat – MaRS Discovery District (2016)
  11. 11. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters
  12. 12. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters Roland Harwood, Open Innovation (2014) (Reproduced) • >250 health startup entrepreneurs • + fin-tech, ed- tech, clean-tech, retail (1000 startups) Invention MaRS 1.0: Building Canada’s Next Generation of Growth Industries November 2016Zayna Khayat – MaRS Discovery District (2016)
  13. 13. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters Single Commercialization Storefront for Toronto’s Academic Institutions Business Accelerator for Emerging Companies Entrepreneurs from across Ontario, and Canada Startups Member Institutions Licensing&Industry Co-development Pg 13 MaRS + MaRS Innovation: IP Commercialization Platform Zayna Khayat – MaRS Discovery District (2016)
  14. 14. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters Health Venture Client Examples Biotechnology Medical Devices Digital Health Consumer Health & Wellness Invention November 2016Zayna Khayat – MaRS Discovery District (2016)
  15. 15. Hurdles to full value capture from med tech 6. Adoption Patients accessing technology Time 1. Evidence 2. Licensing 3. HTA, Coverage decision 4. Funding, fee codes … 5. Procurement (+ Obsolescence of old) 15Zayna Khayat – MaRS Discovery District (2016)
  16. 16. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters Roland Harwood, Open Innovation (2014) (Reproduced) • >250 health startup entrepreneurs • + fin-tech, ed- tech, clean-tech, retail (1000 startups) Invention Adoption Capacity building 6. Corporate 7. Health delivery orgs 1. Reimbursement | adoption 2. Procurement 3. Outcomes Financing 4. Data Liquidity 5. Thought leadership/policy Invention + Adoption = Innovation Bottlenecks MaRS 2.0: Health Innovation Platform November 2016Zayna Khayat – MaRS Discovery District (2016)
  17. 17. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters Pg 17 MaRS’ theory of system change Zayna Khayat – MaRS Discovery District (2016)
  18. 18. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters Health System Academic HTA Regulators Industry + 24 research hospitals + >30 community health orgs + 15 others 1. EXCITE: Pull model for health innovation 18
  19. 19. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters EXCITE INTERNATIONAL SECRETARIAT • Coordinates multinational evaluations for MNEs & SMEs • Facilitates methodologist centre quality frameworks • Advises/assists members in setting up local EXCITE – like operations International Board International Scientific Collab. International Leadership Centres EXCITE International Affiliates P R E L I M I N A R Y C A N A D A ( M A R S ) Develop accepted frameworks to assist EXCITE International affiliates in their work U S U K N E T H E R L A N D S …N Z EXCITE International: Working Model 19
  20. 20. INITIATION DESIGN & PROTOTYPE PROCURE 32 weeks10 weeks Design Discovery Prototype Evaluate Final evaluation Procurement voucher $25K Provider Challenge Briefs Vendor Innovator Briefs Vendor Selection 2. Procurement by Co-Design $50K to help health organizations buy innovative med tech $25K 20Zayna Khayat – MaRS Discovery District (2016)
  21. 21. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters 3. Health outcomes financing: structuring value- based payment schemes with government payers Community-based intervention for individuals with or at risk of high blood pressure Stage: Social Impact Bond Launched Housing first solution for individuals who are homeless and suffering from mental illness Stage: Feasibility complete Enablers Zayna Khayat – MaRS Discovery District (2016)
  22. 22. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters Public Health Agency of Canada Investors • Telus Ventures • RBC Generator • Max Bell • Catherine Donnelly • McConnell • Bealight Pre-Hypertensive Seniors Capital investment Success payments Community Hypertension Prevention Intervention SRDC Success payments • Project development • Deal structuring • Investor relations • Performance mang. support • Independent evaluation Canada’s 1st Health Social Impact Bond
  23. 23. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters Source: Lucien Engelen, Radboud Medical University Centre (Netherlands) 4. MyHealth: Data flows to/thru Patient Zayna Khayat – MaRS Discovery District (2016)
  24. 24. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters 6. MaRS’ Corporate Innovation Platform 29 Thank you 30 Investor Relations contacts Steven Moore, MBA, FCSI, CGA, CFA, CFP Senior Vice President and Treasurer steven_moore@manulife.com (416) 926-6495 Robert Veloso, MBA, CFA Vice President robert_veloso@manulife.com (416) 852-8982 Daniel Kenigsberg, MBA, CFA Assistant Vice President daniel_kenigsberg@manulife.com (416) 852-7208 Adoption Zayna Khayat – MaRS Discovery District (2016)
  25. 25. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters 7. Health Innovation Centre Meetup Building Capacity for Health Innovation in Health Delivery Organizations (Hosted by MaRS) Zayna Khayat – MaRS Discovery District (2016)
  26. 26. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters “A burgeoning new solution economy has emerged, where players from across the spectrum of business, government, philanthropy and social enterprise converge to solve big problems and, in the process, create tremendous public value and new wealth.” 26
  27. 27. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters KEEP CALM & KEEP INNOVATING B E C A U S E T H E F U T U R E M A T T E R S INNOVATION Zayna Khayat, Ph.D. MaRS Health zkhayat@marsdd.com @ZaynaKhayat 27Zayna Khayat – MaRS Discovery District (2016)
  28. 28. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters KEEP CALM & KEEP INNOVATING B E C A U S E T H E F U T U R E M A T T E R S INNOVATION Zayna Khayat, Ph.D. MaRS Health zkhayat@marsdd.com @ZaynaKhayat 28Zayna Khayat – MaRS Discovery District (2016)

Editor's Notes

  • Here is a selection of our current tenants – representing

    Discovery, pool of ideas
    +
    Commercialization partners
    +
    Commercialization support (e.g. legal, business advisory, financial)
  • The MaRS model – support startups, some of which grow, some of which go away, and some of which might embed in an incumbent firm as the way to get scale.

    “An obvious approach for established firms … may be to partner or build innovation ecosystems with small firms. This can be particularly indicated where startup companies tend to cluster, e.g. in industries favored by venture capitalists (like biotechnology or information technology) or ones where there are relatively low barriers to entry”
  • Consumer focused software applications and services, and consumer-like business models for health & well-being products
    Advisors: focused on helping early stage digital health companies
    Startup Curriculum/Training: tailored to the nuances of the healthcare (privacy, data security, regulatory classification, sales strategies, etc.)
  • The MaRS model – support startups, some of which grow, some of which go away, and some of which might embed in an incumbent firm as the way to get scale.

    “An obvious approach for established firms … may be to partner or build innovation ecosystems with small firms. This can be particularly indicated where startup companies tend to cluster, e.g. in industries favored by venture capitalists (like biotechnology or information technology) or ones where there are relatively low barriers to entry”
  • Heart and Stroke Foundation of Canada
    Community Hypertension Awareness Program (“CHAP”)
    Program focused on improving the health of seniors through awareness campaign and blood pressure readings, risk assessments, and catered recommendations to improve lifestyle factors


    Housing First is an evidence-based approach that provides permanent housing at the start of the rehabilitation process for these individuals
    Through At Home / Chez Soi, Housing First has been tested in 5 cities across Canada with very positive results in housing stability, reduction in public sector usage and improvement in quality of life and community functioning.

  • The Obama administration in the Unites States has set ambitious targets for system reform. In at an attempt to reward the quality of care delivered rather than the quantity of care delivered, they have set ambitious targets for Medicare payment reform. By 2018, the goal is for 50% of payments to be tied to quality or value. This reorientation towards value rather than volume represents a bold step to alter the healthcare spending trajectory in order to make health care delivery more affordable in the years ahead.
  • On the back of the investments in data assets, this is now possible… and consumers demanding it, it is also a right
  • Meetups
    Internal slide with weights for close friends/partners
    One pager for key partners
    Stated priorities
    How to connect
    What we need from venture to submit
    Who we sent to them already
    Get feedback from partner

  • Industrial economy
    Then Knowledge economy

    Now solutions economy – new currencies, new value to be unlocked
    Will require creative destruction of existing institutions – and health care system is full of them – gov institutions, delivery institutios, academic institutions.
    Hallmarks of a solutions economy – players from across the spectrum converge ….
    data science will have more to do with improving medicine than anything you will ever learn in medical school or anything currently being researched in the laboratory."
  • ×