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DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Visit us at marsdd.com
Successful
models of public
and private
collaborati...
British Columbia
(5 million)
 PHIX
 Innovation
Boulevard
 Minister Davidson
 IHSTS
Alberta (4 million)
 Strategic Cli...
Ontario: the first
province to have
a Chief
Innovation
Officer for
healthcare
Mandate: use the
$50B health
system to drive...
10%
25%
9%
52%
4%
BOSTON REGION
Employment:
82,000
19%
12%
8%
55%
6%
SAN FRANCISCO REGION
Employment:
63,000
9%
15%
10%
59...
Developingtalent•Growingventures•Openingmarkets
Visit us at marsdd.com
November
2016
MaRS works with partners to catalyze,...
Developingtalent•Growingventures•Openingmarkets
Our Future Matters
November
2016
Developingtalent•Growingventures•Openingmarkets
Visit us at marsdd.com
Dense biocluster + biz + gov + arts
February
2016
Developingtalent•Growingventures•Openingmarkets
Our Future Matters
MaRS: North America’s largest urban
innovation hub
Febr...
Developingtalent•Growingventures•Openingmarkets
Visit us at marsdd.com
Private Public/para-public
Coming in 2016: Starbuck...
DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Our Future Matters
• 40,000 square feet @
MaRS
• 50-70 health startups
inc...
DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Our Future Matters
DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Our Future Matters
Roland Harwood, Open Innovation (2014) (Reproduced)
• >...
DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Our Future Matters
Single Commercialization
Storefront for Toronto’s
Acade...
DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Our Future Matters
Health Venture Client Examples
Biotechnology Medical De...
Hurdles to full value capture from med tech
6. Adoption
Patients
accessing
technology
Time
1. Evidence
2. Licensing
3. HTA...
DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Our Future Matters
Roland Harwood, Open Innovation (2014) (Reproduced)
• >...
DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Our Future Matters
Pg 17
MaRS’ theory of system change
Zayna Khayat – MaRS...
DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Our Future Matters
Health System
Academic HTA
Regulators
Industry
+ 24 res...
DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Our Future Matters
EXCITE INTERNATIONAL
SECRETARIAT
• Coordinates multinat...
INITIATION DESIGN & PROTOTYPE PROCURE
32 weeks10 weeks
Design
Discovery Prototype
Evaluate
Final
evaluation
Procurement
vo...
DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Our Future Matters
3. Health outcomes financing: structuring value-
based ...
DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Our Future Matters
Public Health
Agency of Canada
Investors
• Telus Ventur...
DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Our Future Matters
Source: Lucien Engelen, Radboud Medical University Cent...
DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Our Future Matters
6. MaRS’ Corporate Innovation Platform
29
Thank you
30
...
DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Our Future Matters
7. Health Innovation Centre Meetup
Building Capacity fo...
DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Our Future Matters
“A burgeoning new
solution economy
has emerged, where
p...
DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Our Future Matters
KEEP CALM & KEEP INNOVATING
B E C A U S E T H E F U T U...
DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS
Our Future Matters
KEEP CALM & KEEP INNOVATING
B E C A U S E T H E F U T U...
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"Successful model of public and private collaboration: MaRS", ZAYNA KHAYAT

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Presentation of Zayna Khayat (MaRS Discovery District, Health System Innovation; MaRS EXCITE) at the Forum of the BioRegion of Catalonia, organized by Biocat.

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"Successful model of public and private collaboration: MaRS", ZAYNA KHAYAT

  1. 1. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Visit us at marsdd.com Successful models of public and private collaboration N O V E M B E R 2 5 , 2 0 1 6 Zayna Khayat, Ph.D. Health System Innovation MaRS Discovery District zkhayat@marsdd.com @ZaynaKhayat | @MaRSDD
  2. 2. British Columbia (5 million)  PHIX  Innovation Boulevard  Minister Davidson  IHSTS Alberta (4 million)  Strategic Clinical Networks  TEC Edmonton Ontario (14 million people, $50B health spend)  Office of Chief Innovation Strategist  First Nations health  MaRS EXCITE Quebec (8 million people)  Rx policy  Aggressive reforms Health policy meets industrial policy 2Zayna Khayat – MaRS Discovery District (2016) Canada • 35 million people • $220B health spending
  3. 3. Ontario: the first province to have a Chief Innovation Officer for healthcare Mandate: use the $50B health system to drive the new health economy To read the full report visit www.ohic..ca 3
  4. 4. 10% 25% 9% 52% 4% BOSTON REGION Employment: 82,000 19% 12% 8% 55% 6% SAN FRANCISCO REGION Employment: 63,000 9% 15% 10% 59% 7% SAN DIEGO REGION Employment: 62,000 The Toronto region health cluster 4 Source: Jones, Lang, LaSalle. Life Sciences Cluster Report 2014 Toronto region aiming to be a top 5 human health science clusters. 27% 15% 14% 31% 13% TORONTO REGION Pharma & medicine manufacturing Electromedical instrument manufacturing Medical equipment & supplies manufacturing Testing Labs and R&D Medical & diagnostic laboratories Employment: 38,000
  5. 5. Developingtalent•Growingventures•Openingmarkets Visit us at marsdd.com November 2016 MaRS works with partners to catalyze, accelerate, scale and diffuse innovation. We help entrepreneurs start and grow successful global companies. Together, we help Canada prosper. Our Future Matters. Build the new economy. Improve society. Health | Energy & Environment | Finance & Commerce | Work & Learning
  6. 6. Developingtalent•Growingventures•Openingmarkets Our Future Matters November 2016
  7. 7. Developingtalent•Growingventures•Openingmarkets Visit us at marsdd.com Dense biocluster + biz + gov + arts February 2016
  8. 8. Developingtalent•Growingventures•Openingmarkets Our Future Matters MaRS: North America’s largest urban innovation hub February 2016 MaRS Centre •1.5 million square feet •200+ organizations, ~6,000 people •Science, business (startups to multinationals), investors, enablers •Co-location, incubation, collaboration, resources and local/global networks
  9. 9. Developingtalent•Growingventures•Openingmarkets Visit us at marsdd.com Private Public/para-public Coming in 2016: Starbucks, Facebook Canada headquarters and J&J’s largest global JLABS Accelerator. University of Toronto Asset Management Sample Tenants Examples of MaRS Centre Tenants November
  10. 10. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters • 40,000 square feet @ MaRS • 50-70 health startups incubated • Rx + med tech + digital health + consumer • Access to J&J global networks • No strings attached model 10Zayna Khayat – MaRS Discovery District (2016)
  11. 11. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters
  12. 12. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters Roland Harwood, Open Innovation (2014) (Reproduced) • >250 health startup entrepreneurs • + fin-tech, ed- tech, clean-tech, retail (1000 startups) Invention MaRS 1.0: Building Canada’s Next Generation of Growth Industries November 2016Zayna Khayat – MaRS Discovery District (2016)
  13. 13. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters Single Commercialization Storefront for Toronto’s Academic Institutions Business Accelerator for Emerging Companies Entrepreneurs from across Ontario, and Canada Startups Member Institutions Licensing&Industry Co-development Pg 13 MaRS + MaRS Innovation: IP Commercialization Platform Zayna Khayat – MaRS Discovery District (2016)
  14. 14. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters Health Venture Client Examples Biotechnology Medical Devices Digital Health Consumer Health & Wellness Invention November 2016Zayna Khayat – MaRS Discovery District (2016)
  15. 15. Hurdles to full value capture from med tech 6. Adoption Patients accessing technology Time 1. Evidence 2. Licensing 3. HTA, Coverage decision 4. Funding, fee codes … 5. Procurement (+ Obsolescence of old) 15Zayna Khayat – MaRS Discovery District (2016)
  16. 16. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters Roland Harwood, Open Innovation (2014) (Reproduced) • >250 health startup entrepreneurs • + fin-tech, ed- tech, clean-tech, retail (1000 startups) Invention Adoption Capacity building 6. Corporate 7. Health delivery orgs 1. Reimbursement | adoption 2. Procurement 3. Outcomes Financing 4. Data Liquidity 5. Thought leadership/policy Invention + Adoption = Innovation Bottlenecks MaRS 2.0: Health Innovation Platform November 2016Zayna Khayat – MaRS Discovery District (2016)
  17. 17. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters Pg 17 MaRS’ theory of system change Zayna Khayat – MaRS Discovery District (2016)
  18. 18. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters Health System Academic HTA Regulators Industry + 24 research hospitals + >30 community health orgs + 15 others 1. EXCITE: Pull model for health innovation 18
  19. 19. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters EXCITE INTERNATIONAL SECRETARIAT • Coordinates multinational evaluations for MNEs & SMEs • Facilitates methodologist centre quality frameworks • Advises/assists members in setting up local EXCITE – like operations International Board International Scientific Collab. International Leadership Centres EXCITE International Affiliates P R E L I M I N A R Y C A N A D A ( M A R S ) Develop accepted frameworks to assist EXCITE International affiliates in their work U S U K N E T H E R L A N D S …N Z EXCITE International: Working Model 19
  20. 20. INITIATION DESIGN & PROTOTYPE PROCURE 32 weeks10 weeks Design Discovery Prototype Evaluate Final evaluation Procurement voucher $25K Provider Challenge Briefs Vendor Innovator Briefs Vendor Selection 2. Procurement by Co-Design $50K to help health organizations buy innovative med tech $25K 20Zayna Khayat – MaRS Discovery District (2016)
  21. 21. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters 3. Health outcomes financing: structuring value- based payment schemes with government payers Community-based intervention for individuals with or at risk of high blood pressure Stage: Social Impact Bond Launched Housing first solution for individuals who are homeless and suffering from mental illness Stage: Feasibility complete Enablers Zayna Khayat – MaRS Discovery District (2016)
  22. 22. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters Public Health Agency of Canada Investors • Telus Ventures • RBC Generator • Max Bell • Catherine Donnelly • McConnell • Bealight Pre-Hypertensive Seniors Capital investment Success payments Community Hypertension Prevention Intervention SRDC Success payments • Project development • Deal structuring • Investor relations • Performance mang. support • Independent evaluation Canada’s 1st Health Social Impact Bond
  23. 23. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters Source: Lucien Engelen, Radboud Medical University Centre (Netherlands) 4. MyHealth: Data flows to/thru Patient Zayna Khayat – MaRS Discovery District (2016)
  24. 24. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters 6. MaRS’ Corporate Innovation Platform 29 Thank you 30 Investor Relations contacts Steven Moore, MBA, FCSI, CGA, CFA, CFP Senior Vice President and Treasurer steven_moore@manulife.com (416) 926-6495 Robert Veloso, MBA, CFA Vice President robert_veloso@manulife.com (416) 852-8982 Daniel Kenigsberg, MBA, CFA Assistant Vice President daniel_kenigsberg@manulife.com (416) 852-7208 Adoption Zayna Khayat – MaRS Discovery District (2016)
  25. 25. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters 7. Health Innovation Centre Meetup Building Capacity for Health Innovation in Health Delivery Organizations (Hosted by MaRS) Zayna Khayat – MaRS Discovery District (2016)
  26. 26. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters “A burgeoning new solution economy has emerged, where players from across the spectrum of business, government, philanthropy and social enterprise converge to solve big problems and, in the process, create tremendous public value and new wealth.” 26
  27. 27. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters KEEP CALM & KEEP INNOVATING B E C A U S E T H E F U T U R E M A T T E R S INNOVATION Zayna Khayat, Ph.D. MaRS Health zkhayat@marsdd.com @ZaynaKhayat 27Zayna Khayat – MaRS Discovery District (2016)
  28. 28. DEVELOPINGTALENT•GROWINGVENTURES•OPENINGMARKETS Our Future Matters KEEP CALM & KEEP INNOVATING B E C A U S E T H E F U T U R E M A T T E R S INNOVATION Zayna Khayat, Ph.D. MaRS Health zkhayat@marsdd.com @ZaynaKhayat 28Zayna Khayat – MaRS Discovery District (2016)

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