CELLULAR RESPIRATIONI.   GENERAL     A. HOW GET FOOD – AUTOTROPH         or   HETEROTROPH     B. COUPLE REACTIONS         ...
Fig. 6-02                                   Sunlight energy                                   enters ecosystem            ...
C. TYPES OF CELLULAR RESPIRATION C1. AEROBIC – USES O2  C6H12O6 + 6 O2                6 CO2   +   6 H 2O                  ...
II. OVERVIEW OF GLUCOSE METABOLISMA.   MITOCHONDRIUM        OUTER MEMBRANE       INNER MEMBRANE             CRISTAE      I...
Fig. 4-20                        Outer                                 TEM                      membrane               Inn...
B. GENERAL REACTIONS – overall pathway is exergonicGLYCOLYSIS                         CITRIC ACID CYCLE & e-              ...
III. SPECIFICSA. GLYCOLYSIS – glucose activation and energy harvestREACTION        # CARBONS/                    REACTION ...
III. SPECIFICSA. GLYCOLYSIS – glucose activation and energy harvestREACTION          # CARBONS/                   REACTION...
END PRODUCTS OF                GLYCOLYSIS•   2 PYRUVATE MOLECULES – moves into mitochondrium matrix•   2 NET ATP – Usually...
B. Citric acid cycle –   Produces large amounts of ATP with O2 acting as e- acceptor.   Occurs in the Mtiochondrium PYRUVA...
2. KREBS CYCLE                                 CoA                                           CITRATE   OXALOACETATE       ...
3. ALL COMPOUNDS AT THE END OF THE KREBS CYCLE – THIS               IS FOR TWO PYRUVATES               CO2    ATP        N...
C. ELECTRON TRANSPORT CHAINC1. General1. e-s from the high energy compounds go   into the e- transport chain.2. The e-s mo...
4. The e- s reach the end of the chain   where they are accepted by oxygen and   hydrogen to form water.5. ATP actually fo...
Fig. 6-11a  Space  between                                                                                H+  membranes   ...
C2. SPECIFICS                  GENERATED                    CONVERT TO ATP                  per Glucose (= 2 pyruvate)1. G...
IV. ANEROBIC A. GENERAL     1. Animals – glycolysis & lactate fermentation     2. Plants – glycolysis & alcoholic fermenta...
LACTATE FERMENTATION   ALCOHOLIC FERMENTATION 2                       2PYRUVATE                PYRUVATE             NADH  ...
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2. cellular respiration

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2. cellular respiration

  1. 1. CELLULAR RESPIRATIONI. GENERAL A. HOW GET FOOD – AUTOTROPH or HETEROTROPH B. COUPLE REACTIONS 1. Metabolic Pathway – couple reactions where exergonic drive endergonic C6H12O6 + 6 O2 6 CO2 + 6 H 2O 36 ADP 36ATP ENDERGONIC 2. Enzymes – increase the rate of a reaction
  2. 2. Fig. 6-02 Sunlight energy enters ecosystem Photosynthesis C6H12O6 CO2 Glucose Carbon dioxide O2 H2O Oxygen Water Cellular respiration ATP drives cellular work Heat energy exits ecosystem
  3. 3. C. TYPES OF CELLULAR RESPIRATION C1. AEROBIC – USES O2 C6H12O6 + 6 O2 6 CO2 + 6 H 2O get 36 ATP C2. ANEROBIC – DOES NOT USE O2 C6H12O6 OTHER COMPOUNDS
  4. 4. II. OVERVIEW OF GLUCOSE METABOLISMA. MITOCHONDRIUM OUTER MEMBRANE INNER MEMBRANE CRISTAE INTERMEMBRANE SPACE MATRIX
  5. 5. Fig. 4-20 Outer TEM membrane Inner membrane Cristae Matrix Space between membranes
  6. 6. B. GENERAL REACTIONS – overall pathway is exergonicGLYCOLYSIS CITRIC ACID CYCLE & e- TRANSPORT CHAIN Where: Where: cytoplasm mitochondrium General: General Does not use O2 Uses O2 Energy from substrate Most ancient of pathways Overall pathway: Overall pathway:Glucose 2 pyruvate Pyruvate 6CO2 + 6H2O net 2 ATP 36 ATP 2 NADH
  7. 7. III. SPECIFICSA. GLYCOLYSIS – glucose activation and energy harvestREACTION # CARBONS/ REACTION COMPOUND NAME MOLECULE NAME & EXPLAIN 6 carbons (1 molecule) GLUCOSE 2 ATPGLUCOSE 2 ADPACTIVATION +P 6 carbons (1 molecule) FRUCTOSE BIPHOSPHATE P P ENERGY HARVEST
  8. 8. III. SPECIFICSA. GLYCOLYSIS – glucose activation and energy harvestREACTION # CARBONS/ REACTION COMPOUND NAME MOLECULE NAME & EXPLAIN 6 carbons (1 molecule) GLUCOSE 2 ATPGLUCOSE 2 ADPACTIVATION + P 6 carbons (1 molecule) FRUCTOSE BIPHOSPHATE P P 3 carbons (2 molecules) G3P 2 ADP + 2P 2 ADP + 2P 2 ATP 2 ATP ENERGY HARVEST NAD + H NAD + H NADH NADH 3 carbons (2 molecules) PYRUVATE
  9. 9. END PRODUCTS OF GLYCOLYSIS• 2 PYRUVATE MOLECULES – moves into mitochondrium matrix• 2 NET ATP – Usually stays in cytoplasm to be used by the cell 2 used as activation energy (GLUCOSE ACTIVATION) 4 made when producing pyruvate (ENERGY HARVEST)• 2 NADH – High energy compound that moves to e- transport chain.
  10. 10. B. Citric acid cycle – Produces large amounts of ATP with O2 acting as e- acceptor. Occurs in the Mtiochondrium PYRUVATE 1. Acetyl CoEnzyme A Coenzym NAD+ EACH PYRUVATE GENERATES: e +H 1 NADH CO 2 NAD 1 CO2 (RELEASED) H ACETYL CoA CoA
  11. 11. 2. KREBS CYCLE CoA CITRATE OXALOACETATE 3 NAD+ ATP 3 NADH ADP + P FAD FADH 2 2 CO 2 EACH PYRUVATE GENERATES: 3 NADH 1 FADH2 1 ATP 2 CO2
  12. 12. 3. ALL COMPOUNDS AT THE END OF THE KREBS CYCLE – THIS IS FOR TWO PYRUVATES CO2 ATP NADH FADH2 0 2 2 0 GLYCOLYSIS made directly 2 0 2 0 ACETYL Co-A ACTIVATION 4 2 6 2 KREB CYCLE Made directly
  13. 13. C. ELECTRON TRANSPORT CHAINC1. General1. e-s from the high energy compounds go into the e- transport chain.2. The e-s move “down” the chain and energy is released during this “fall”.3. The energy is used to pump H+ from the matrix into the intermembrane space.
  14. 14. 4. The e- s reach the end of the chain where they are accepted by oxygen and hydrogen to form water.5. ATP actually forms from the energy released when H+ moves from the intermembrane space, through ATP Synthase, and into the matrix to combine with oxygen.
  15. 15. Fig. 6-11a Space between H+ membranes H+ H+ H+ H+ H+ Electron H+ H+ carrier + H+ H + H H + H+ Protein complex Inner mitochondrial membrane FADH2 FAD Electron flow H+ 1 2 O2 + 2 H + H 2O NADH NAD+ ADP + P ATP H+ H+ H+ H+ H+ Matrix Electron transport chain ATP synthase
  16. 16. C2. SPECIFICS GENERATED CONVERT TO ATP per Glucose (= 2 pyruvate)1. GLYCOLYSIS 2 NADH 6 ATP2. ACETYL CoA 2 NADH 6 ATP3. KREBS 6 NADH 18 ATP 2 FADH2 4 ATP3 ATP per NADH2 ATP per FADH2
  17. 17. IV. ANEROBIC A. GENERAL 1. Animals – glycolysis & lactate fermentation 2. Plants – glycolysis & alcoholic fermentation B. GLYCOLYSIS – make the same as aerobic 2 pyruvate 2 net ATP 2 NADH
  18. 18. LACTATE FERMENTATION ALCOHOLIC FERMENTATION 2 2PYRUVATE PYRUVATE NADH NADH NAD + + NAD + + H H 2 ETHANOL 2 + LACTATE 2 CARBON DIOXIDE

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