Causes of gout

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The main causes of gout can be attributed to a high level of uric acid in the blood. The high level is due to the metabolism (breakdown) of purines that exist in the body, mainly from the foods we eat. If the kidneys are not working properly, the uric acid builds up forming monosodium uric acid crystals that deposit in the joints and surrounding soft tissues (tophi). This causes extreme pain, swelling, and inflammation of the affected area. Other causes of gout can include: lymphoma, some cancers, psoriasis, diabetes and hypertension.

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Causes of gout

  1. 1. Causes of Gout - What are the Main Causes of Gout? What causes gout? The main cause of this condition can be attributed to a high level of uric acid in the blood. The high level is due to the metabolism (breakdown) of purines that exist in the body, mainly from the foods we eat. Uric acid is the product of that breakdown, that if not sufficiently excreted by the kidneys, causes the uric acid level to rise (hyperuricemia). If the kidneys are not working properly, the uric acid builds up forming monosodium uric acid crystals that deposit in the joints and surrounding soft tissues (tophi). This causes extreme pain, swelling, and inflammation of the affected area. There are other factors that can cause gout to develop, and is what we will discuss here. Causes of gout
  2. 2. Other causes of gout: Being overweight: Weighing more than you should puts you at risk for many other conditions, such as heart disease. Gout is more prevalent in those who are overweight and the risk for this disorder gets higher as you gain more weight. Eating the wrong foods, sedentary lifestyle, and some chronic conditions, such as hypothyroidism can contribute to weight gain. Gender: It is well known that men are more susceptible for the development of gout than women. Age: Although more men than women have gout, there is a higher incidence of gout in women as they progress in age, particularly among women of menopausal age. Family history: Genetics also play a part in developing gout. If you have a close family member with gout, your risks for getting it are higher. Diabetes: There is a link between diabetes and gout, due to the complications of circulatory problems associated with diabetes, such as kidney disease. Kidney damage due to poor circulation can prevent the elimination of uric acid from the body, causing increased uric acid levels, leading to the formation of uric acid crystals in the joints, resulting in a gout attack. Causes of gout
  3. 3. Medications: Certain medications are known to pave the way for gout development. These medications include: * Diuretics (water pills) * Anti rejection drugs, such as cyclosporin * Aspirin * Levodopa, * Aminophylline, * Niacin * Anti-TB medications, such as Rifampin Dieting: Crash diets can cause gout due to the sudden lack of calories, as well as the over production of lactic acid, which can prevent the kidneys from excreting uric acid. Eating foods high in purines: Most all the foods we eat contain purines. It is recommended that you eat these foods in moderation. Most all foods that contain purines are healthy foods that are good for the body. Therefore, eating these foods in moderation, as well as drinking plenty of water will help to reduce your chances of future gout attacks. Beverages: Some beverages contain high levels of purines, such as beer and wine. Again, moderation is the key. Excessive exposure to lead has been found to bring on an attack of gout. Causes of gout
  4. 4. Other causes of gout can include: * Lymphoma * Some cancers * Psoriasis * Diabetes * Hypertension If you are taking any medications that may cause you to develop gout, speak with your health care provider to voice any concerns you may have. Causes of gout
  5. 5. To watch Video Report References: Causes of Gout [Google.com] gout (414, 10); acid (111, 9); health (111, 9); uric (108, 9); arthritis (93, 9); joint (68, 9); treatment (56, 10); symptoms (54, 9); may (51, 7); blood (50, 8); crystals (48, 5); urate (48, 5); what (47, 8); information (43, 8); medical (41, 9); pain (41, 9); attacks (39, 9); disease (38, 8); inflammation (38, 6); attack (35, 7); joints (34, 9); home (34, 8); causes (33, 10); risk (32, 8); body (30, 8); new (29, 5); people (27, 7); acute (26, 6); see (26, 6); skin (26, 7); hyperuricemia (26, 4); kidney (26, 7); help (25, 8); national (25, 6); Causes of gout
  6. 6. rheumatology (25, 4); cause (25, 6); conditions (24, 8); diagnosis (24, 9); overview (24, 5); nhs (23, 3); usually (22, 8); levels (22, 4); medicine (22, 6); women (22, 8); high (22, 6); mayo (21, 2); webmd (21, 3); prevention (20, 7); doctor (20, 3); topics (20, 7); info (20, 5); news (20, 7); men (20, 7); research (20, 6); diseases (20, 5); a-z (19, 4); lead (19, 5); common (19, 8); free (18, 6); colchicine (18, 2); next (18, 5); medications (18, 4); take (18, 6); gouty (18, 5); policy (17, 7); first (17, 8); medicines (17, 5); diet (17, 8); emedicine (16, 4); clinic (16, 2); top (16, 3); site (16, 7); tests (16, 7); related (16, 6); form (16, 9); return (15, 3); medicinenet (15, 3); nsaids (15, 2); lifestyle (15, 3); privacy (15, 9); level (15, 7); comments (14, 4); healthy (14, 5); fluid (14, 6); toe (14, 8); article (14, 6); swelling (14, 6); drugs (14, 6); clinical (14, 4); accessed (13, 2); share (13, 5); questions (13, 7); references (13, 4); big (13, 8); occurs (13, 6); march (13, 4); many (13, 7); use (13, 5); intake (13, 2); search (12, 5); condition (12, 5); tissues (12, 5); medscape (12, 3); rxlist (12, 3); bedwetting (12, 3); need (12, 6); signs (12, 5); better (12, 5); living (12, 5); terms (12, 7); last (12, 6); page (12, 5); links (12, 3); library (12, 5); musculoskeletal (12, 4); stones (12, 6); including (12, 4); develop (12, 4); used (12, 4); alcohol (12, 5); caused (11, 7); institute (11, 3); slideshow (11, 2); allopurinol (11, 2); check (11, 6); foundation (11, 4); tools (11, 5); bmj (11, 2); physician (11, 5); effective (11, 3); available (11, 3); occur (11, 4); normal (11, 5); chronic (11, 5); renal (11, 2); advertising (10, 3); education (10, 3); red (10, 6); deposits (10, 3); painful (10, 5); eat (10, 5); copd (10, 3); synovial (10, 4); factors (10, 5); part (10, 4); content (10, 4); foods (10, 7); american (10, 3); drug (10, 3); pressure (10, 4); kidneys (10, 4); surgery (10, 3); navigation (9, 3); inflammatory (9, 2); affects (9, 5); index (9, 5); learn (9, 6); prevent (9, 3); called (9, 4); ask (9, 5); find (9, 6); management (9, 3); contact (9, 7); tophi (9, 4); knee (9, 4); commonly (9, 4); answers (9, 5); pseudogout (9, 4); urine (9, 4); number (9, 4); purines (9, 6); metabolism (9, 2); increases (9, 4); bookmark (8, 2); resources (8, 6); med (8, 2); disclaimer (8, 2); read (8, 3); reviewed (8, 6); ways (8, 5); tips (8, 2); advice (8, 6); control (8, 4); known (8, 3); baby (8, 3); menopause (8, 6); depression (8, 2); languages (8, 2); due (8, 2); patient (8, 5); ard (8, 2); pdf (8, 2); list (8, 6); crystal (8, 2); associated (8, 3); sleep (8, 3); choices (8, 2); found (8, 3); reduce (8, 7); local (8, 3); similar (8, 6); decrease (8, 4); patients (8, 2); encyclopedia (7, 2); sitemap (7, 3); date (7, 4); swollen (7, 6); elevated (7, 3); document (7, 2); emedicinehealth (7, 2); complications (7, 5); services (7, 5); reserved (7, 5); rights (7, 5); careers (7, 3); map (7, 5); updated (7, 4); avoid (7, 2); diagnosed (7, 6); buildup (7, 6); man (7, 3); drink (7, 3); cancer (7, 4); history (7, 3); affected (7, 5); articles (7, 4); oxford (7, 2); guide (7, 4); rheum (7, 2); february (7, 2); dictionary (7, 5); treatments (7, 6); especially (7, 5); united (7, 4); additional (7, 4); chondrocalcinosis (7, 2); test (7, 4); years (7, 5); time (7, 5); reference (7, 3); syndrome (7, 3); affect (7, 5); damage (6, 3); accessibility (6, 3); college (6, 2); issues (6, 4); e-mail (6, 2); basics (6, 2); hot (6, 5); write (6, 2); latest (6, 3); institutes (6, 3); experienced (6, 2); term (6, 4); exercises (6, 3) uric acid (110, 9); gouty arthritis (16, 5); privacy policy (14, 7); acid crystals (14, 4); health information (13, 5); big toe (13, 8); kidney stones (11, 6); blood pressure (10, 4); skin diseases (9, 3); institute arthritis (9, 3); national institute (9, 3); font size (9, 3); women health (9, 3); attack gout (9, 4); diagnosis gout (9, 4); acid levels (9, 3); joint inflammation (8, 2); gout symptoms (8, 4); gout slideshow (8, 2); health check (8, 5); gout what (8, 3); gout attack (8, 3); gout causes (8, 5); risk factors (8, 5); gout national (8, 4); medical dictionary (8, 4); gout attacks (8, 5); urate crystals (8, 3); develop gout (8, 3); attacks gout (8, 2); related topics (7, 2); medical education (7, 2); mayo foundation (7, 2); high blood (7, 3); medical advice (7, 5); rights reserved (7, 5); causes gout (7, 4); what gout (7, 3); health news (7, 5); national library (7, 2); risk gout (7, 2); acute gout (7, 2); symptoms gout (6, 2); college rheumatology (6, 2); american college (6, 2); document Causes of gout
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  8. 8. report task force (3, 2); evidence based recommendations (3, 2); eular evidence based (3, 2); white blood cells (3, 3) gout national institute arthritis (6, 3); blood level uric acid (3, 2); medical advice diagnosis treatment (3, 3); provide medical advice diagnosis (3, 3); what women really need (3, 3); escisit ann rheum dis (3, 2); therapeutics escisit ann rheum (3, 2); including therapeutics escisit ann (3, 2); studies including therapeutics escisit (3, 2); clinical studies including therapeutics (3, 2); international clinical studies including (3, 2); eular evidence based recommendations (3, 2) 1 word (255) Causes of gout
  9. 9. g o u t 4 1 4 a c i d 1 1 1 h e a l t h 1 1 1 Causes of gout
  10. 10. gout (414, 10); acid (111, 9); health (111, 9); uric (108, 9); arthritis (93, 9); joint (68, 9); treatment (56, 10); symptoms (54, 9); may (51, 7); blood (50, 8); crystals (48, 5); urate (48, 5); what (47, 8); information (43, 8); medical (41, 9); pain (41, 9); attacks (39, 9); disease (38, 8); inflammation (38, 6); attack (35, 7); joints (34, 9); home (34, 8); causes (33, 10); risk (32, 8); body (30, 8); new (29, 5); people (27, 7); acute (26, 6); see (26, 6); skin (26, 7); hyperuricemia (26, 4); kidney (26, 7); help (25, 8); national (25, 6); rheumatology (25, 4); cause (25, 6); conditions (24, 8); diagnosis (24, 9); overview (24, 5); nhs (23, 3); usually (22, 8); levels (22, 4); medicine (22, 6); women (22, 8); high (22, 6); mayo (21, 2); webmd (21, 3); prevention (20, 7); doctor (20, 3); topics (20, 7); info (20, 5); news (20, 7); men (20, 7); research (20, 6); diseases (20, 5); a-z (19, 4); lead (19, 5); common (19, 8); free (18, 6); colchicine (18, 2); next (18, 5); medications (18, 4); take (18, 6); gouty (18, 5); policy (17, 7); first (17, 8); medicines (17, 5); diet (17, 8); emedicine (16, 4); clinic (16, 2); top (16, 3); site (16, 7); tests (16, 7); related (16, 6); form (16, 9); return (15, 3); medicinenet (15, 3); nsaids (15, 2); lifestyle (15, 3); privacy (15, 9); level (15, 7); comments (14, 4); healthy (14, 5); fluid (14, 6); toe (14, 8); article (14, 6); swelling (14, 6); drugs (14, 6); clinical (14, 4); accessed (13, 2); share (13, 5); questions (13, 7); references (13, 4); big (13, 8); occurs (13, 6); march (13, 4); many (13, 7); use (13, 5); intake (13, 2); search (12, 5); condition (12, 5); tissues (12, 5); medscape (12, 3); rxlist (12, 3); bedwetting (12, 3); need (12, 6); signs (12, 5); better (12, 5); living (12, 5); terms (12, 7); last (12, 6); page (12, 5); links (12, 3); library (12, 5); musculoskeletal (12, 4); stones (12, 6); including (12, 4); develop (12, 4); used (12, 4); alcohol (12, 5); caused (11, 7); institute (11, 3); slideshow (11, 2); allopurinol (11, 2); check (11, 6); foundation (11, 4); tools (11, 5); bmj (11, 2); physician (11, 5); effective (11, 3); available (11, 3); occur (11, 4); normal (11, 5); chronic (11, 5); renal (11, 2); advertising (10, 3); education (10, 3); red (10, 6); deposits (10, 3); painful (10, 5); eat (10, 5); copd (10, 3); synovial (10, 4); factors (10, 5); part (10, 4); content (10, 4); foods (10, 7); american (10, 3); drug (10, 3); pressure (10, 4); kidneys (10, 4); surgery (10, 3); navigation (9, 3); inflammatory (9, 2); affects (9, 5); index (9, 5); learn (9, 6); prevent (9, 3); called (9, 4); ask (9, 5); find (9, 6); management (9, 3); contact (9, 7); tophi (9, 4); knee (9, 4); commonly (9, 4); answers (9, 5); pseudogout (9, 4); urine (9, 4); number (9, 4); purines (9, 6); metabolism (9, 2); increases (9, 4); bookmark (8, 2); resources (8, 6); med (8, 2); disclaimer (8, 2); read (8, 3); reviewed (8, 6); ways (8, 5); tips (8, 2); advice (8, 6); control (8, 4); known (8, 3); baby (8, 3); menopause (8, 6); depression (8, 2); languages (8, 2); due (8, 2); patient (8, 5); ard (8, 2); pdf (8, 2); list (8, 6); crystal (8, 2); associated (8, 3); sleep (8, 3); choices (8, 2); found (8, 3); reduce (8, 7); local (8, 3); similar (8, 6); decrease (8, 4); patients (8, 2); encyclopedia (7, 2); sitemap (7, 3); date (7, 4); swollen (7, 6); elevated (7, 3); document (7, 2); emedicinehealth (7, 2); complications (7, 5); services (7, 5); reserved (7, 5); rights (7, 5); careers (7, 3); map (7, 5); updated (7, 4); avoid (7, 2); diagnosed (7, 6); buildup (7, 6); man (7, 3); drink (7, 3); cancer (7, 4); history (7, 3); affected (7, 5); articles (7, 4); oxford (7, 2); guide (7, 4); rheum (7, 2); february (7, 2); dictionary (7, 5); treatments (7, 6); especially (7, 5); united (7, 4); additional (7, 4); chondrocalcinosis (7, 2); test (7, 4); years (7, 5); time (7, 5); reference (7, 3); syndrome (7, 3); affect (7, 5); damage (6, 3); accessibility (6, 3); college (6, 2); issues (6, 4); e-mail (6, 2); basics (6, 2); hot (6, 5); write (6, 2); latest (6, 3); institutes (6, 3); experienced (6, 2); term (6, 4); exercises (6, 3) 6, exercises 3 Causes of gout
  11. 11. http://www.webmd.com/a-to-z- (2) 1 2 guides/gout-topic-overview http://www.medicinenet.com/gout/article. (3) 2 2 htm http://www.emedicinehealth.com/gout/art (9) 3 2 icle_em.htm 6, term 4 (1 1 http://en.wikipedia.org/wiki/gout 3 ) http://www.medicinenet.com/gout/articl (3 2 1 e.htm ) (5 3 http://www.gout.com/ 1 ) (6 4 http://www.nhs.uk/conditions/gout 1 ) 6, experienced 2 http://www.medicinenet.com/gout/article. (3) 1 3 htm http://www.emedicinehealth.com/gout/art (9) 2 3 icle_em.htm 6, institutes 3 http://www.medicinenet.com/gout/article. (3) 1 1 htm 2 http://www.nlm.nih.gov/medlineplus/gout (7) 4 Causes of gout
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  13. 13. http://www.emedicinehealth.com/gout/ar (9) 5 1 ticle_em.htm 6, basics 2 http://www.mayoclinic.com/health/gout (4 1 2 /ds00090 ) http://www.nlm.nih.gov/medlineplus/go (7 2 4 ut.html ) 6 e-mail , 2 ( http://www.mayoclinic.com/health/gout/ds0 4 1 5 0090 ) ( http://www.nlm.nih.gov/medlineplus/gout.h 7 2 1 tml ) issues 6, 4 http://www.mayoclinic.com/h 1 (4) 1 ealth/gout/ds00090 http://www.nlm.nih.gov/medl 2 (7) 2 ineplus/gout.html http://hcd2.bupa.co.uk/fact_s 3 (8) 1 heets/html/gout.html http://www.podiatrychannel.c 4 (10) 2 om/gout/index.shtml Causes of gout
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  15. 15. http://www.medicinenet.com/gout/article. (3 2 1 htm ) http://www.mayoclinic.com/health/gout/ds (4 3 1 00090 ) http://hcd2.bupa.co.uk/fact_sheets/html/g (8 4 2 out.html ) http://www.emedicinehealth.com/gout/arti (9 5 2 cle_em.htm ) 7, syndrome 3 (1 1 http://en.wikipedia.org/wiki/gout 5 ) http://www.medicinenet.com/gout/articl (3 2 1 e.htm ) http://www.nlm.nih.gov/medlineplus/go (7 3 1 ut.html ) 7, reference 3 (1 1 http://en.wikipedia.org/wiki/gout 1 ) http://www.webmd.com/a-to-z- (2 2 1 guides/gout-topic-overview ) http://www.nlm.nih.gov/medlineplus/gout (7 3 5 .html ) 7, time 5 1 http://en.wikipedia.org/wiki/gout (1) 1 Causes of gout
  16. 16. http://www.webmd.com/a-to-z- (2) 2 2 guides/gout-topic-overview (5) 3 http://www.gout.com/ 2 http://hcd2.bupa.co.uk/fact_sheets/html (8) 4 1 /gout.html http://www.podiatrychannel.com/gout/i (10 5 1 ndex.shtml ) 7, years 5 (1) 1 http://en.wikipedia.org/wiki/gout 2 http://www.webmd.com/a-to-z- (2) 2 1 guides/gout-topic-overview http://www.medicinenet.com/gout/article. (3) 3 1 htm (6) 4 http://www.nhs.uk/conditions/gout 2 http://www.emedicinehealth.com/gout/art (9) 5 1 icle_em.htm 7, test 4 (1) 1 http://en.wikipedia.org/wiki/gout 2 http://www.webmd.com/a-to-z- (2) 2 2 guides/gout-topic-overview Causes of gout
  17. 17. http://www.nlm.nih.gov/medlineplus/gou (7) 3 1 t.html http://hcd2.bupa.co.uk/fact_sheets/html/ (8) 4 2 gout.html 7, chondrocalcinosis 2 (1 1 http://en.wikipedia.org/wiki/gout 6 ) http://www.nlm.nih.gov/medlineplus/go (7 2 1 ut.html ) 7, additional 4 (1) 1 http://en.wikipedia.org/wiki/gout 2 http://www.webmd.com/a-to-z- (2) 2 1 guides/gout-topic-overview http://www.medicinenet.com/gout/article. (3) 3 2 htm http://www.emedicinehealth.com/gout/art (9) 4 2 icle_em.htm 7, united 4 (1) 1 http://en.wikipedia.org/wiki/gout 3 http://www.medicinenet.com/gout/article. (3) 2 2 htm 3 http://hcd2.bupa.co.uk/fact_sheets/html/ (8) 1 Causes of gout
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