Research for Better HealthKOLLING CONNECTIONNewsletter | August 2012KOLLING BONE & JOINT                                  ...
From the CEO                                                          The Kolling Knowledge (KK) series of free health for...
KOLLING KNOWLEDGE HEALTH FORUMS                                      Moderated by Dr John D’Arcy      STROKE PREVENTION   ...
KOLLING CANCER                                                                         60 SECONDS WITHKolling researchers ...
KOLLING MOTHER & BABY  Population health researcher, Dr                           particularly about the risks in subseque...
Pub2Pub Charity Fun Run and Walk - Sunday 26 August  In its 20th year, the Pub2Pub Charity Fun Run and         with family...
New Partnership with ASX Thomson Reuters Charity  The Kolling Foundation is delighted to be one of  the 22 chosen charitie...
“thank you”                        TO ALL OUR SUPPORTERS  Kolling Foundation donations over $1,000                        ...
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Kolling Foundation Newsletter August 2012


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Kolling Foundation's quarterly newsletter August 2012.

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Kolling Foundation Newsletter August 2012

  1. 1. Research for Better HealthKOLLING CONNECTIONNewsletter | August 2012KOLLING BONE & JOINT The majority of patients with osteoarthritis don’t want to have surgery. Kolling researchers focus on preventing surgery and reducing pain by developing medical therapies that can meaningfully intervene and change the course of this disease. For Anne Ashford, this intervention came at a time when she needed it most. She was becoming increasingly immobilised by her condition, “The pain in my knee rapidly got worse and I needed a stick. I couldn’t stand for even five minutes without it hurting and I couldn’t do short walks. I was always looking around for seats. My knees ached all through the night and I couldn’t sleep,” she said. After seeing several orthopaedic surgeons she had an arthroscopy booked for one knee and expected possible replacement of the other. She was then referred to Rheumatologist, Prof David Hunter, who prescribed a weight loss goal of 10 per cent of her bodyweight and an exercise regime that involved knee-focused exercise in hydrotherapy, as part of a research study. Within six months on the new diet and exercise plan Anne saw marked improvements and she is very pleased with the results, “My knee pain is very much reduced, my general activity levels and fitness have increased significantly and I can manage my arthritis much better Anne Ashford was able to avoid surgery and is experiencing without medication. This is a very good result for me less pain after taking part in a Kolling research study. and I wish I had done it 10 years earlier. Everyone should know about this,” she said. Researchers discover way to prevent surgery and The study, led by Prof David Hunter, shows that patients who undertook diet and exercise to lose 10% of their reduce pain for bodyweight reduced their pain, on average, by 50%. osteoarthritis sufferers The average pain reduction with an anti-inflammatory medication is 20 – 30%. Anne Ashford has been plagued by osteoarthritis for many years, suffering crippling pain in her knees. After This medication-free approach to reduce pain and avoid taking part in a study at the Kolling Institute involving surgery for osteoarthritis sufferers is just one of the many intensive diet and exercise, she has found her pain studies Kolling Bone & Joint experts are conducting significantly reduced and she has avoided surgery. to make a difference in the lives of those enduring this agonising disease. Osteoarthritis affects three million Australians. Within the next 10 years this will increase to six million due We still need your help. To make a donation and help to three risk factors; an increase in obesity, joint injury people like Anne please visit and an ageing population. KOLLING FOUNDATION | ABN 83 128 360 174 | Registered Charity Number 157521 AUGUST 2012 Level 12 Kolling Building, Royal North Shore Hospital, Reserve Rd, St Leonards NSW 2065 Ph 1300 KOLLING (1300 565 546) | Fax 02 9926 5928 | |
  2. 2. From the CEO The Kolling Knowledge (KK) series of free health forums has been a great success so far and we look forward to engaging more of the community in our work in the future. Thanks to our MC Dr John D’Arcy and the Hon Jillian Skinner, Minister for Health and Medical Research, for attending our KK Cancer Forum and to our KK supporters Westfield, North Shore Private Hospital, PwC and Willoughby City Council. We are grateful to all our supporters for your ongoing commitment and welcome the ASX Thomson Reuters Charity Foundation as our new partner. As the funding arm of the Kolling Institute we are keen to engage new supporters so please don’t hesitate to contact me if you would like to help us in our vision to improve healthcare now and in the future. Welcome to the August issue of Kolling Connection. Knowledge is what we’re about at the Kolling. Helen Connealy Searching for causes, prevention and cures requires CEO, Kolling Foundation intelligence, good direction and patience. Knowing how to use that knowledge is vital in our path to improving healthcare for everyone in the community. Health Minister Attends Kolling Knowledge The Minister for Health and Medical Research, Jillian The next Kolling Knowledge cancer event is Breast Skinner, was an honorary guest at the Improving and Ovarian Cancer on Tuesday 9 October. This is Cancer Care Kolling Knowledge Health Forum, the a free event and everyone is welcome. Places are second event in the new series of health forums the limited so please register online at Kolling Foundation launched in May. or phone 9926 4904. Minister Skinner said these events were important to engage the community and to highlight the relevance of Kolling’s research to the community as well as a forum for sharing the outcomes being achieved by the Kolling Institute. This health forum shared insights about the future direction of cancer research and informed on how today’s treatments will be used to improve patient care and quality of life. Renowned physician and Kolling Knowledge ambassador, Dr John D’Arcy, lead a panel of Kolling cancer experts, Prof Robert Baxter, Prof Stephen Clarke and Assoc Prof Nick Pavlakis, who explained how their vision for more personalised cancer treatments and a holistic approach to cancer care is put into practice by doctors. Minister Skinner with Prof Stephen Clarke.2 AUGUST 2012
  3. 3. KOLLING KNOWLEDGE HEALTH FORUMS Moderated by Dr John D’Arcy STROKE PREVENTION LIFE AFTER BIRTH Wednesday 22nd August Tuesday 4th September BREAST & OVARIAN CANCER RHEUMATOID ARTHRITIS Tuesday 9th October Tuesday 16th October Hear from experts on a range of important health topics as they provide insight into new treatments and highlight future research at the Kolling. Registration is FREE but essential as places are limited. Register online at or phone 9926 4904 Registration & refreshments: 5:30pm - 6:00pm Event time: 6:00pm - 7:30pm 2012 Venue: Level 5 Kolling Building, Reserve Road Royal North Shore Hospital, St Leonards Follow Kolling’s news and events on Facebook and Twitter AUGUST 2012
  4. 4. KOLLING CANCER 60 SECONDS WITHKolling researchers focus on cancer vaccine Tumour Bank Officer Ussha PillaiResearchers at the Kolling Institute are currently focusing on a cancer vaccinethat has the potential to improve the life expectancy and survival rates of patientssuffering from a brain tumour.Each year about 1,400 cases of malignant brain cancer are diagnosed in Australiaand about 1,100 people die from the disease every year. The most commonmalignant brain cancer, high grade glioma (HGG), is almost 100% fatal.Over the past five years Kolling researchers have been working on ways tomake a vaccine that will stop a tumour from recurring. Using animal modelsresearchers are looking at treating brain tumours with vaccines made from theindividual brain tumour. The tumour proteins are linked directly to a bacterialprotein which makes the individual’s immune system see the tumour as foreign.Study results are promising, showing up to 60% complete remission withextended survival times in the remaining 40%. How important is the Tumour BankResearchers are planning to progress this research into human trials, with the aim to cancer research?of decreasing recurrent brain tumours and improving healthcare for a group of The Tumour Bank is a vital part ofpatients that currently have limited hope. cancer research. It gives researchers opportunities to study changes in“If a patient is having surgery to remove a tumour or even if we can get a biopsy cancer cells, which will help themof the tumour, we can make a personalised vaccine”, says Kolling researcher, Dr develop new ways of diagnosingChris Weir, who is leading the project. and treating cancer.Although the vaccine can work in conjunction with chemotherapy, researchers Best part of your job? The best part of my job is that eachbelieve the optimal time to administer the vaccine will be after chemotherapy, day is different. Each person thatonce the patient’s immune system has sufficiently recovered. gives consent for tumour banking has a different story to tell and I get“This vaccine could be another weapon in the arsenal against cancer,” says Dr to work with amazing and talentedWeir. researchers in a state of the art research facility.If you’d like to support Kolling Cancer research that can make a difference,please make a donation at Most challenging part of your job? The most challenging part of my job is keeping up with the high volume of work and variety of tasks involved with tumour banking, such as getting consent from patients, collecting samples, preparing samples for researchers to use and maintaining the tumour bank databases. What inspires you? Giving people the opportunity to be part of tumour banking, as this is something positive coming out of situations that are often difficult and distressing. Best piece of advice you’ve been given? “Whatever job you end up doing, make it good science,” from my finalDr Chris Weir leads cancer research into a vaccine that will one day give hope to lecture at university.patients suffering from a brain tumour.4 AUGUST 2012
  5. 5. KOLLING MOTHER & BABY Population health researcher, Dr particularly about the risks in subsequent pregnancies. We also let clinicians know our findings so they Jane Ford, is helping women achieve can ensure their patients who are at risk will attend better outcomes in childbirth a hospital where there is 24 hour access to blood supply. We’re also looking at variation across hospitals in treatments offered, for example transfusions Postpartum following PPH. If we can identify practices associated haemorrhage with low transfusion rates we may be able to prevent some women having to have a transfusion, which in (PPH) occurs itself can be associated with adverse outcomes. in 10% of births Does your research impact on other areas of mother worldwide and baby research? and is one We’re starting to take a similar approach to other conditions such as pre-eclampsia (high blood of the three pressure in pregnancy). We’re looking at what’s leading causes happening across time - is there an increase or of maternal decrease in the incidence, what might be driving the death. increase or decrease, what are the risks in subsequent pregnancies. We have access to a large amount of data that allows us to follow women’s pregnancy outcomes over time, which is quite unique – there What are you currently researching? aren’t many countries in that position. We’re lucky to I’m involved in mother and baby research that looks be able to use this rich data source to explore other at state-wide data to identify trends and outcomes of rare conditions. particular aspects of childbirth. My area of research is focused on mothers and their outcomes, in particular What do you see as the greatest advances in your postpartum haemorrhage (PPH), which is excessive area of population health research in the last 5-10 bleeding after birth. years? The capability and advances in technology that How common is PPH? have increased capacity to examine state-wide PPH occurs in 10% of births worldwide and is one data sources on births and hospital admissions of the three leading causes of maternal death. In is transforming the way we can generate new Australia there has been an increase in PPH. From knowledge, and my team at the Kolling are at the 1994 to 2009 there was an increase from 5% to 8% forefront of this work both here in Australia and of women giving birth. After travelling overseas to a internationally. conference I discovered this was also happening in other developed countries, such as Canada and the US. One focus of our research is to find what’s driving this increase. At this stage we’ve ruled out factors such as increase in maternal age and caesareans, We’ve been able to follow however we still don’t have the answers. up women who’ve had PPH and determine their risk in Can you determine if PPH will occur in subsequent subsequent pregnancies. pregnancies? We’ve been able to follow up women who’ve had PPH and determine their risk in subsequent pregnancies. You can help improve the health of mothers and Our research has indicated that 1 in 3 women who their babies by donating to Kolling Mother & Baby at had a previous PPH will have another one. or phone 02 9926 4904. How will your research impact on patient outcomes? A lot of our research is tailored to counselling women,5 AUGUST 2012
  6. 6. Pub2Pub Charity Fun Run and Walk - Sunday 26 August In its 20th year, the Pub2Pub Charity Fun Run and with family and friends. Walk aims to be bigger, better and more fun than ever before and hopes to raise $150,000. If you’d like to get involved and raise much-needed funds for medical research simply follow these quick Organised by the Rotary Club of Brookvale in and easy steps: conjunction with the Newport Arms Hotel, the 13km course starts on the sand at Dee Why Surf Club and 1. Register online at winds its way along the picturesque northern beaches, ending at iconic pub, The Newport Arms Hotel, and 2. Build your own web page where family and friends providing participants with spectacular scenery along can sponsor you online at the way. Entrants always look forward to grabbing their 3. Nominate the Kolling Foundation as the charity favourite refreshment and a bite to eat at the Newport you’d like to support. Arms as a reward for their efforts and to celebrate Thank You to Cure Cancer and Can Too Cure Cancer Australia has been supporting early achievements she has also recently been appointed as career researchers at the Kolling Institute for many Laboratory Research Director of the Bill Walsh Cancer years. This year Dr Viive Howell received a two year Research Laboratory at the Kolling Institute. research grant from Cure Cancer Australia. For information about tours of the Kolling email To share the important cancer work that Kolling or call 02 9926 4904. researchers conduct, a group of Cure Cancer and Can Too supporters visited the Kolling for an early morning The Kolling welcomed Cure Cancer & Can Too supporters for tour and breakfast on 5th June. a breakfast tour of the Kolling building. Led by Dr Howell, guests were taken through the cancer laboratories and given insights into the daily routine of researchers. In particular they were shown the Kolling Tumour Bank, the largest and most comprehensive tumour bank in NSW, housing a range of different tumours stored in high tech refrigeration and cooling systems. The Kolling is grateful to Cure Cancer for its support as Dr Howell has a successful research career with recognition through numerous awards, publications, grants and presentations. In recognition of her6 AUGUST 2012
  7. 7. New Partnership with ASX Thomson Reuters Charity The Kolling Foundation is delighted to be one of the 22 chosen charities to be supported by the ASX Thomson Reuters Charity Foundation which organises fundraising events in conjunction with the Financial Markets. In particular the Charity Sailing Regatta at Middle Harbour Yacht Club, the annual golf day and charity dinner and a wonderful art union raffle contributed to a 2011 fundraising total of $1.1 million. The Kolling Foundation will have art union raffle tickets with great prizes to sell later this year. If you are interested in volunteering to help us sell the tickets please contact the foundation office on 02 9926 4904 The Charity Sailing Regatta organised by ASX Thomson or email Reuters Charity Foundation. Kolling Researchers Receive Pursuit of Excellence Award Kolling researchers were recognised by the Rotary Club of Lane Cove on 22nd May for their outstanding research at the Kolling Institute. Congratulations to Professor Lyn March, Associate Professor Deborah Marsh, Associate Professor Christine Roberts and Professor Carolyn Sue who each received a Pursuit of Excellence Award. We’d like to thank the Rotary Club of Lane Cove for their generous donation which will go towards the continued work of Kolling research. The Kolling team were on hand to celebrate at the awards presentation. The Entertainment Book is a local restaurant and activity guide providing hundreds of 25% to 50% off and 2-for-1 offers from fine restaurants, cafes, attractions, activities and accommodation. The Kolling Foundation is delighted to offer Entertainment Books online and your purchase of this great value book will ensure that 20% of the cost of each book is donated back to research at Kolling. To purchase your book visit : AUGUST 2012
  8. 8. “thank you” TO ALL OUR SUPPORTERS Kolling Foundation donations over $1,000 Kolling Institute Seminar Sponsors For privacy reasons we are not listing names of individual Edwards Group Pty Ltd major donors but thank each and every one for their great Sapphire Bioscience Pty Ltd generosity in supporting our research. POCD Scientific DKSH Australia Pty Ltd Organisations HD Scientific Rotary Club of Lane Cove Thermo Fisher Scientific Australia North Shore Private Hospital Life Technologies Westfield Sarstedt Australia Donations in memory of the following people: Genesearch Amelie Antoinette Charles Sigma Aldrich Ruth Wearne Peter Nam A special thanks to Amy Nadaskay, Joe Gritching Kat Clarke and the wonderful team at Lech Pazdzior Monogram who have made our new Robert Luscombe website look amazing - Donations in celebration: Drs Keith & Eileen Ong’s 25th wedding anniversary Kolling Knowledge Partners I’d like to support Kolling’s vital medical research. My contact details My area(s) of interest Title: First name: Kolling Mother & Baby Kolling Diabetes Kolling Cancer Kolling Heart Last Name: Kolling Bone & Joint Address: All medical research at Kolling Email: Phone: My donation details Donations of $2 and above are tax deductible. Thank you for your support. Donation amount $ My cheque/money order made payable to Kolling Please complete this coupon and mail it to: Foundation is enclosed Kolling Foundation Level 12 Kolling Building OR Please deduct the above amount once monthly Royal North Shore Hospital Reserve Road from my Visa Mastercard Amex St Leonards NSW 2065 ph: 1300 KOLLING (1300 565 546) Card number e: Expiry date CCV No. Cardholder’s name Signature Research for Better Health8 AUGUST 2012