Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.

Normal Neuromuscular Junction Action

12,560 views

Published on

A slide show demonstrating normal neuromuscular junction action leading to muscle contraction

Published in: Health & Medicine, Technology
  • I am doing a presentration of the NMJ physaiology. May I use ur yslide ? kIndly email it to me ennythea@aol.com Thanks /
       Reply 
    Are you sure you want to  Yes  No
    Your message goes here

Normal Neuromuscular Junction Action

  1. 1. Neuromuscular Junction Normal Neuromuscular Junction Action
  2. 2. Normal Neuromuscular Junction <ul><li>Electrical impulse arrives at motor terminal </li></ul>
  3. 3. Normal Neuromuscular Junction <ul><li>Electrical impulse arrives at motor terminal </li></ul><ul><li>Influx of Ca2+ at motor terminal </li></ul>
  4. 4. Normal Neuromuscular Junction <ul><li>Electrical impulse arrives at motor terminal </li></ul><ul><li>Influx of Ca2+ at motor terminal </li></ul><ul><li>Release of Acetylcholine </li></ul>
  5. 5. Normal Neuromuscular Junction <ul><li>Electrical impulse arrives at motor terminal </li></ul><ul><li>Influx of Ca2+ at motor terminal </li></ul><ul><li>Release of Acetylcholine </li></ul><ul><li>Diffusion of Ach across synaptic cleft to nicotinic receptors on motor end plate </li></ul>
  6. 6. Normal Neuromuscular Junction <ul><li>Electrical impulse arrives at motor terminal </li></ul><ul><li>Influx of Ca2+ at motor terminal </li></ul><ul><li>Release of Acetylcholine </li></ul><ul><li>Diffusion of Ach across synaptic cleft to nicotinic receptors on motor end plate </li></ul><ul><li>Depolarisation of end plate </li></ul>
  7. 7. Normal Neuromuscular Junction <ul><li>Electrical impulse arrives at motor terminal </li></ul><ul><li>Influx of Ca2+ at motor terminal </li></ul><ul><li>Release of Acetylcholine </li></ul><ul><li>Diffusion of Ach across synaptic cleft to nicotinic receptors on motor end plate </li></ul><ul><li>Depolarisation of end plate </li></ul><ul><li>Action potential generated by depolarisation </li></ul>
  8. 8. Normal Neuromuscular Junction <ul><li>Electrical impulse arrives at motor terminal </li></ul><ul><li>Influx of Ca2+ at motor terminal </li></ul><ul><li>Release of Acetylcholine </li></ul><ul><li>Diffusion of Ach across synaptic cleft to nicotinic receptors on motor end plate </li></ul><ul><li>Depolarisation of end plate </li></ul><ul><li>Action potential generated by depolarisation </li></ul><ul><li>Muscle contraction </li></ul>
  9. 9. Normal Neuromuscular Junction <ul><li>Electrical impulse arrives at motor terminal </li></ul><ul><li>Influx of Ca2+ at motor terminal </li></ul><ul><li>Release of Acetylcholine </li></ul><ul><li>Diffusion of Ach across synaptic cleft to nicotinic receptors on motor end plate </li></ul><ul><li>Depolarisation of end plate </li></ul><ul><li>Action potential generated by depolarisation </li></ul><ul><li>Muscle contraction </li></ul><ul><li>Rapid removal of Ach </li></ul>By rapid diffusion & action of acetyl- cholinesterase
  10. 10. Normal Neuromuscular Junction <ul><li>Electrical impulse arrives at motor terminal </li></ul><ul><li>Influx of Ca2+ at motor terminal </li></ul><ul><li>Release of Acetylcholine </li></ul><ul><li>Diffusion of Ach across synaptic cleft to nicotinic receptors on motor end plate </li></ul><ul><li>Depolarisation of end plate </li></ul><ul><li>Action potential generated by depolarisation </li></ul><ul><li>Muscle contraction </li></ul><ul><li>Rapid removal of Ach </li></ul>

×