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Regulatory Status of Genome Editing in Vietnam

  1. Regulatory Status of Genome Editing in Vietnam
  2. Natural area 331,698 km2 km2 Density 288 persons Urban population 34.6% Rural population 65.4% Vietnam Hoang Sa Truong Sa Population 95.5 millions (2018)
  3. Overview • The agricultural sector (including forestry and fishery) has contributed 15,3 % to total national GDP (2017). • Agricultural production activities are a key source of livelihood for 65 % of the rural population. 8 agro-ecological zones of Viet Nam
  4. CROPS Annual Crop Production for 2018 Planted area (million ha) Yield (ton/ha) Production (million tons) 7.57 5.81 44.00 1.09 4.70 5.13 0.534 19.36 10.34 0.96 Varied 17.10 Rice Maize Cassava Vegetable MARD Annual Report 2018
  5. Industrial crops production 2018 123 987 688 1,620 965 1,140 149 255 302 261 950 8,800 CROPS Tea Coffee Rubber Black pepper Cashew Fruits Planted area (thousand ha) Production (thousand tons) MARD Annual Report 2018
  6. Achievements in agriculture  Fast and sustainable growth in a long-term.  Ensure food security.  Export increase, high positions of many agro-products in the world market (Vietnam became a major exporter for many agricultural commodities)  Policy reform (arable land was allocated to farmers and farmer household was determined as core production unit).
  7. Challenges and constrains in Vietnamese agriculture  Agro-processing industry is still under-developed and creates small added value. Vietnam mainly exports raw materials with low added value  High input cost, low quality and low competitiveness of many agro-products  Business registration, applicable technical standards, audit and assurance labeling, traceability of origins have been neglected  Environmental pollution  Diseases on crops and livestock is more and more complicated  Huge effect of climate change
  8. Current status of genome editing research in Vietnam
  9. Application of Genome editing in Vietnam Increase of yield traits Improvement of qualitative traits Enhancement of disease resistance Increase of abiotic stress tolerance Generation of herbicide resistanceCRISPR/Cas9 Functional identification of genes Basic reseach Applied research Two kind of research
  10. Rice 1. Using genome editing as a tool for identification and characterization of unknown genes involved in yield and abiotic stress tolerance traits in rice 2. Application of genome editing technologies to improve disease resistance (bacterial leaf blight disease) and quatity (fragrance) of Vietnamese popular rice varieties
  11. 1. Targeting genes related to herbicide receptor and flowering in cassava for herbicide tolerance and enhanced flowering for breeding 2. Evaluation of the effects of the gene editing on the flowering and herbicide tolerance Collaboration among AGI, JIRCAS and RIKEN Cassava Construction of MeFT-editing T-DNA vectors 1-bp insertion (+T)
  12. Positive regulators Negative regulators Target GmNAC29 and GmHyPRP1 by GE technology National Key Lab of plant cell technology, AGI soybean
  13. Regulatory Status genome editing application in Vietnam
  14. Plant Breeding Innovation (PBI)/genome editing tech is categorized as a form of biotech, which is increasingly popular in the world, however quite new with Vietnamese scientists. There are no PBI policies in place for Vietnam. Biotech was promoted in the Prime Minister’s Decision No. 11/2006 on National Target Program on Development and Application of Biotechnology in Agriculture 2020. The program is intended to extend to 2030 with possible inclusion of PBI/genome editing. Regulatory Status
  15. Biotech application and import have been promoted in PM’s Decision No. 2194 on National Seed Program 2020. The extension beyond 2020 is still unclear. Plant breeding and seed quality are currently regulated in the Seed Ordinance (2004) but this will soon be replaced by the Law on Crop Production (LCP), which will become effective on January 1, 2020. PBI/genome editing is not yet regulated under Law on Crop Production Regulatory Status
  16. PBI/genome editing should be treated as non-GM and be promoted as a tool for plant variety improvements (especially in disease tolerance), which remains a controversial issue globally Developing a policy for PBI/genome editing is highly recommended to address not only the country’s growing demand for animal feed but also the expansion of export markets Personal opinion
  17. Genome editing technology is an opportunity for us to exchange new knowledge with colleagues in the region and countries around the world. The application of genome editing technology is also an opportunity to improve productivity and resistance/tolerance of some major crop varieties in Vietnam to cope with climate change. Personal opinion
  18. ●Development of PBI/ Genome Editing Material The materials will focus on the current status of PBI/genome editing development around the world and the implications for Vietnam. The materials will provide consistent references for scientists and policy makers in Vietnam. Some activities in the near future
  19. ● Workshop Organization VAAS will organizing several workshops targeting different stakeholders involved in the seed industry, including plant scientists, policy makers, traders etc. in order to introduce PBI/ genome editing The first workshop for scientists is proposed for November 2019 Some activities in the near future
  20. ● Development of a Web-Based Platform This will provide Vietnamese scientist, regulators and other interest stakeholders access to the most current PBI/genome editing materials, database and news. The website will be established in 2020, as an additional or extension to the existing website of VAAS or a member institute and be fully operated by 2021. Some activities in the near future
  21. Collaborate with us For more information, please contact: Vietnam Academy of Agricultural Sciences Vinh Quynh, Thanh Tri, Hanoi, Vietnam Tel: 84-2438615487; Fax: 84-2438613937

Editor's Notes

  1. Vietnam is an active member of Association of South-East Asia Nations (ASEAN) Possessing more than 90 million people (in 2015), Vietnam is considered to have a young population structure, a prerequisite for eco-social development. With 300,000 km2 of overall square, the average population density of Vietnam is about 274 persons per km2 but actual population distribution is not equal. About one-third of Vietnamese people are clustered in urban areas while more than two-third of these live dispersedly in rural areas.