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Leukemia

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Leukemia

  1. 1. Leukemia<br />
  2. 2. Leukemia Overview<br />Cancerous cells fill up the bone marrow and prevent healthy red cells, platelets, and mature white cells (leukocytes) from being made<br />Tumor suppressor genes are deactivated<br />
  3. 3. Four Types of Leukemia:<br />Leukemia<br />Acute<br />Chronic<br />Chronic Myeloid<br />Leukemia (CML)<br />Acute Lymphocytic Leukemia (ALL)<br />Chronic Lymphocytic<br />Leukemia (CLL)<br />Acute Myeloid Leukemia (AML)<br />
  4. 4. Chronic Lymphocytic Leukemia (CLL)<br />CLL cells (mutations) multiply and replace normal white blood cells in bone marrow<br />Spreads to blood stream<br />Failure of bone marrow<br />Almost never occurs in children<br />
  5. 5. Chronic Myeloid Leukemia (CML)<br /><ul><li> Increased and unregulated growth of mainly myeloid (bone marrow) cells in bone marrow
  6. 6. Accumulation of these mutated cells into the blood.
  7. 7. Mainly affects adults</li></li></ul><li>Acute Lymphocytic Leukemia (ALL)<br />Malignant (immature) white blood cells continuously multiply and are overproduced in the bone marrow<br />Causes damage and death by crowding out normal cells and by spreading to other organs<br />Most common in children but can also occur in adults<br />
  8. 8. Acute Myeloid Leukemia (AML)<br />Abnormal fast multiplying myeloid cells replace healthy cells, causing bone marrow to fail<br />Occurs in children and adults<br />
  9. 9. Symptoms of Leukemia<br />May be easily bruised<br />Night sweats<br />Bleed excessively<br />Feeling sick, fatigued, flu-like symptoms<br />Nausea/swollen belly<br />Headaches<br />
  10. 10. Diagnosis<br />Blood tests<br />Bone marrow aspiration<br />Bone marrow biopsy<br />Blood cell counts<br />Chest x-rays<br />Spinal tap (looks for leukemia in CSF)<br />Physical exam <br />
  11. 11. Treatments<br />Chemotherapy (main treatment)<br />Bone marrow transplant<br />Radiation treatments<br />Stem cell transplant<br />Biological therapy<br />Clinical treatments (new medicines)<br />
  12. 12. Sources<br />http://www.webmd.com/cancer/tc/leukemia-topic-overview?page=2<br />http://www.leukemia-lymphoma.org/all_page.adp?item_id=7059<br />http://www.nlm.nih.gov/medlineplus/ency/article/000532.htm<br />http://www.lls.org/all_page?item_id=7059<br />http://www.leukemia-research.org/page.aspx?pid=214<br />http://www.buzzle.com/articles/history-of-leukemia.html<br />http://rebeccanelson.com/leukemia/biology.html<br />http://www.montana.edu/wwwai/imsd/cancer/van1/vwtreatments.htm<br /> <br />

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