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Self Experimentation: The Best Science?

An overview of science and the scientific method or discipline, to include the principle of falsifiability for scientific propositions. This is then applied to my own years of self experimentation in a context of weight gain/loss and degraded/improved health and fitness.

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Self Experimentation: The Best Science?

  1. 1. Self-Experimentation The Best Science? Richard Nikoley,
  2. 2. What is Science?• The intellectual and practical activity encompassing the systematic study of the structure and behavior of the physical and natural world through observation and experiment• A systematically organized body of knowledge on a particular subject• Knowledge of any kind
  3. 3. How is Science Done?• Make observations and study them• Find associations• Form a hypothesis; make a prediction• Test hypothesis
  4. 4. Principles of Science• Falsifiability• Try to disprove• Avoid confounders• No number of failures to disprove confirms an hypothesis while a single falsification relegates the hypothesis to the shitcan
  5. 5. Bullshit Science• Confirmation bias• Grant whores• Pet theories• Follow the money• Political policy
  6. 6. Good vs. Useful Science• Even the best controlled, randomized intervention study utilizing impeccable methods and presenting clear conclusions is of limited relevance to YOU!• You still have to test it on yourself
  7. 7. Principles of Self- Experimentation• Sound foundation (heroin will make you feel good)• Manage confounders• Confront your biases• Be honest with yourself• Never stop learning
  8. 8. My Self-Experiments• Walking 3 miles per day for 5-6 years (5,000 - 6,000 miles).
  9. 9. Result: 35-40 lbs Gained
  10. 10. #FAIL
  11. 11. Resistance Training
  12. 12. Paleo Eating
  13. 13. Intermittent Fasting
  14. 14. Fasted Training
  15. 15. Cold Water Exposure
  16. 16. Result: ~60 lbs lost
  17. 17. #WINNING
  18. 18. Continuing Experiments• Low-carb vs. Moderate vs. Cycling• No Soap; No Shampoo• Various Intermittent Fasting Methods• Starch (potatoes, white rice)• Dairy and nut reduction elimination• Fermented vegetables• Extended cold water exposure• Barefoot
  19. 19. The Whole Animal• News & Current Events Obsession• 1 in 300 millionth say in your own affairs• Care about whose going to rule you next• Going one God further
  20. 20.