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lymphadenopathy

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Lymphadenopathy
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lymphadenopathy

  1. 1. Lymphadenopathy
  2. 2. Intended learning outcome: 1 2 3 4 5 6 2 Define lymphadenopathy. Differentiate between generalized and localized lymphadenopathy. Recognize the causes of generalized lymphadenopathy. Recognize the causes of localized lymphadenopathy. Understand the role of dentist in patient with lymphadenopathy. Enumerate the management of lymphadenopathy
  3. 3. Definition 3 Lymphadenopathy: refers to lymph nodes that are abnormal in: 1. Size 2. Number 3. Consistency (Abnormalities may be localized or generalized) [1]
  4. 4. 4 Generalized lymphadenopathy is defined as enlargement of more than 2 noncontiguous lymph node groups. Regional lymphadenopathy it involves enlargement of a single node or multiple contiguous nodal regions. . [1] [1]
  5. 5. Generalized lymphadenopathy 5 infections 1. Infections viral infections • Epstein-Barr Virus • Herpes simplex • Mumps • Adenovirus • HIV Bacterial infections • Group A streptococcus • Mycobacteria: typical and atypical • Anaerobic bacteria • Diphtheria [1][3]
  6. 6. Generalized lymphadenopathy 6 1. Infections Fungal / Parasitic infections • Candida • Cryptococcus • Histoplasmosis • Toxoplasmosis 2. Metabolic • Lipid storage diseases • Endocrine disease : Hyperthyroidism Gaucher’s diseases [1][3] [1][3]
  7. 7. Generalized lymphadenopathy 7 • Rheumatoid arthritis 3. Hypersensitivity • Mixed connective tissue diseased. • Systemic lupus erythematous • Drug hypersensitivity 4. Neoplastic • Hodgkin’s disease • non- Hodgkin’s lymphomas • leukemia Hodgkin’s disease non- Hodgkin’s lymphomas [1][3] [1][3]
  8. 8. 8 Regionallymphadenopathy SUBMANDIBULAR • Pharyngitis • Nasopharyngeal tumour Cervical • Toxoplasmosis • Pharyngitis • Oral and dental infections • Infectious mononucleosis [1][3]
  9. 9. 9 Regionallymphadenopathy Occipital • Secondary to local skin infection • Rubella Preauricular • Local skin infection • Catscratch disease [1][ 3]
  10. 10. 10 Regionallymphadenopathy Axillary • Local infection • Catscratch disease • Lymphoma Supraclavicular • Lymphoma • Tuberculosis • Histoplasmosis [1][3]
  11. 11. Role of Dentist • Extraoral physical examination: [2][3]
  12. 12. 12 • Extraoral physical examination: [2][3]
  13. 13. Investigation and Treatment 13 Tuberculin Skin Testing BLOOD Chest X-ray Biopsy Treatment: • No specific treatment for lymphadenopathy • Treatment of the cause is the rule [2][3]
  14. 14. infection Hypersensitivity Neoplastic Other disorders Rheumatoid arthritis Hodgkin's disease Mixed connective tissue diseased. Non-Hodgkin’s lymphomas Systemic lupus erythematous Lymphocytic leukemia Adenovirus Drug hypersensitivity Hairy cell leukemia Herpes simplex malignant histiocytosis Congestive heart failure amyloidosis Hisriocytosis x Group A streptococcus Diphtheria HIV Candida Sjögren’s syndrome Serum sickness Catleman's disease Sarcoidosis Dermatopathic lymphadenitis Histiocytic necrotizing lymphadenitise summary
  15. 15. References 1. Dan L. Longo, Anthony S. Fauci, Dennis L. Kasper, Stephen L. Hauser, J. Larry Jameson, Joseph Loscalzo, (eds.) Harrison's Principles of Internal Medicine,18th edition .United state:McGraw Hill Professional, 2011.p.465,466,467. 2. Steven L. Bricker, B C Decker, Robert P. Langlais, Craig S. Miller. Oral Diagnosis, Oral Medicine, and Treatment Planning, Second Edition. Lippincott Williams & Wilkins,1994.p.67,73,74. 3. Martin S. Greenberg, Michael Glick . Burket's Oral Medicine: Diagnosis and Treatment, Tenth Edition. B.C. Decker,2002.p.18,19.
  16. 16. Thank you for your attention! Do you have any questions ;-) Thank you

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