Literature Search andSynthesisAlyssa Green, BBA, MLISDecember 21, 2011
Objective To find evidence-based recommendations for the practice of Vitamin D testing.
Method Searched numerous databases ◦ The Cochrane Library, PubMed, EMBASE, AHRQ, Google Scholar and TRIP. Used various search techniques ◦ Synonyms: Vitamin D, 25-hydroxy-vitamin D, 25-hydroxyvitamin D, 25-OH D ◦ Boolean operators AND, OR, NOT to combine terms ◦ Truncation to broaden results Used backward and forward citation linking
Inclusion Criteria Evidence-based ◦ Systematic reviews, synthesis, summaries, clinical guidelines, and evidence-based narrative reviews Timely ◦ Within the last five years Critical evaluation ◦ Meet JAMA‟s “Users Guides to Evidence- based Medicine” evaluative criteria
Limitations Undefined information need Literature search had very broad scope Time constraints Working alone on project
Synthesis Overview Background ◦ Currently a lot of interest in vitamin D ◦ Literature divided on its impact on various health outcomes ◦ No agreement on validity of vitamin D deficiency epidemic Key findings ◦ Agreement that routine testing is unnecessary ◦ Could be need for testing in certain „high- risk‟ populations