1. Understanding Hepatitis-B Prof Arif M. Siddiqui MBBS(KE);MRCP(UK);FRCP(London) FRCP(Edin);FRCP(Glasg) AllamaIqbal Medical College/Jinnah Hospital Lahore
2. Prologue There has been an explosion of information on Hepatits B in the last few years and this many doctors have not been able to grasp fully. New management guidelines have emerged. I will, in this short time, try to explain few basic important facts on which the understanding and management of this disease is based.
3. PAKISTAN 151 millionpopulation 35% Urban 65% Rural 22 millionchildren under 5 years 6.6 million childreninfected by HBV before the age of 5 years go on to develop Chronic Hepatitis B infection. Hepatitis 2.6% prevalence among general public 3.8% prevalence among pregnant women Ref: WHO/MDG
6. Global distribution of HBV genotypes (A to H) A, D B,C G A, C, B, D, G B, C A,D F, H E F A * Defined by divergence in the entire genome sequence > 8%.
7. Hepatitis B Source: Centers for Disease Control and Prevention, USA Revised December 2003