Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.

Allergy

13,337 views

Published on

Allergic reaction includes the degranulation process, shown here

  • Be the first to comment

Allergy

  1. 1. Allergy Degranulation Process
  2. 2. Allergy <ul><li>Activated mast cells go through a process called degranulation. They release histamine and other chemicals causing inflammation. </li></ul>
  3. 3. Allergy <ul><li>The antigen floats around the body … </li></ul>
  4. 4. Allergy <ul><li>IgE antibod ies find allergen and attach themselves to it. </li></ul>
  5. 5. Allergy <ul><li>IgE binds to IgE receptors on surface of mast cells (a type of immune cell) </li></ul><ul><li>This is a kind of FC receptor. </li></ul>
  6. 6. Allergy <ul><li>Stored mediators (4) such as histamine, proteases, chemokines and heparine are released from granules (5) </li></ul>
  7. 7. Allergy <ul><li>N ewly formed mediators also released (prostaglandins, leukotrienes, thromboxanes amd PAF) </li></ul>
  8. 8. Allergy <ul><li>Produced by Allergy-Details.com </li></ul><ul><li>Material from Wikipedia </li></ul><ul><li>Image by Paweł Kuźniar </li></ul>

×