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We present an exploratory analysis of the causal interactions among global change drivers of regime shifts, based on information collated in the Regime Shifts Database*. We reviewed the documented evidence of over 20 policy-relevant regime shifts in ecosystems. Information on the dynamics of each regime shift was synthesized using causal-loop diagrams, a generic structure map of the system. We then identified the main drivers of change, the key impacts on ecosystem services, as well as possible cross-scale interactions among regime shifts drivers using network analysis.