Digital’s Transformative Power Across R&D: Keeping pace with Stakeholder Expectations

1. Digital’s transformative power across R&D: Keeping pace with stakeholder expectations Accenture Life Sciences Rethink Reshape Restructure…for better patient outcomes

2. 2Copyright © 2016 Accenture All rights reserved. € 4.4B total number of app users by 20171 Every minute, +190k mobile apps are downloaded worldwide4 Soon there will be an app for everything… …And platforms for everything 50B connected IoT devices by 20202 Data Explosion 44ZB of data by 2020, A 10x increase since 20133 Data will be king of the brave new world With stakeholders’ extensive digital adoption, we believe a more holistic embrace of digital is essential for R&D transformation

3. 3Copyright © 2016 Accenture All rights reserved. Our recent research of 76 top R&D leaders finds organizations are considering important strategic imperatives for future success5… Pivot to the Patient Advance to the Next Generation of R&D Operating Models Drive Scientific & Operational Excellence

4. Patient Connection and Engagement Digitally Empowered Workforce Data-driven Insights and Decision Making 4Copyright © 2016 Accenture All rights reserved. And digital capabilities can be applied across each of these major industry imperatives Digital capabilities create: Pivot to the Patient Advance to the Next Generation of R&D Operating Models Drive Scientific & Operational Excellence

5. 5Copyright © 2016 Accenture All rights reserved. R&D organizations lag behind their stakeholders’ expectations in adopting digital… And companies often find themselves questioning: Digital can help drive value in R&D: What value? 1 Digital is already transforming R&D: Are we ready? Digital R&D transformation is happening: How do we get there? 2 3

6. 6 Digital can help drive value in R&D: What Value? Copyright © 2016 Accenture All rights reserved. 1 Patient Connection and Engagement Helps generate and document a holistic, shareable picture of patient health and improve understanding of the patient journey and disease areas. Digitally Empowered Workforce Creates the opportunity to operate differently, with improved productivity both within and across functions of an R&D organization Data-driven Insights and Decision Making Makes it possible for companies to aggregate and synthesize data that have not traditionally been combined to generate insights that inform R&D activities and decisions

7. 7 Patient connection and engagement through digital solutions improves the overall patient experience and outcomes Copyright © 2016 Accenture All rights reserved. Patient connection and engagement opportunities: • Better understand diseases and shape product programs • Enhance the patient experience • Improve patient outcomes

8. 8 A digitally empowered workforce creates the opportunity to operate differently Copyright © 2016 Accenture All rights reserved. Digitally empowered workforce opportunities: • Change the traditional way of thinking and operating • Enhance the employee experience • Embed digital savviness in your organization

9. 9 Data-driven insights and decisions making helps R&D organizations focus on higher value, strategic activities Copyright © 2016 Accenture All rights reserved. Data-driven insights and decision making opportunities: • Improve scientific decisions earlier in the R&D processes • Shift the R&D way of working to a more informed and predictive approach • Support cross-functional activities, collaboration and decision making

10. 10Copyright © 2016 Accenture All rights reserved. 10 There is opportunity to move beyond disconnected pilots and isolated initiatives to embrace digital and realize its value Copyright © 2016 Accenture All rights reserved. Your digital journey Patient Connection and Engagement Data-driven Insights and Decision Making Digitally Empowered Workforce

11. 11 Digital is already transforming R&D: Are you ready? Copyright © 2016 Accenture All rights reserved. To assess your organization’s digital adoption readiness, we suggest asking functional and technology leadership teams the following: Current state: What is your digital footprint today? Future state: Have you defined it? Alignment: Is your organization onboard with it? Path forward: Do you have a plan to achieve it? 2

12. 12 Digital R&D Transformation: How do you get there? Copyright © 2016 Accenture All rights reserved. Some R&D organizations appear ‘digital’ yet few have built the necessary capabilities to realize digital’s potential value. To do that, companies should consider the following actions: Assess the current digital footprint within your R&D organization and across the enterprise Create the ‘art of the possible’ future state inspired by examples within and outside the industry Seek to understand stakeholder needs and expectations to shape optimal experiences across therapeutic areas and R&D functions Align on the right vision, strategy and prioritization for organizational buy-in Build a roadmap to achieve the desired future state, inclusive of timelines, resources, and budget 3

14. 14 About the Authors 14Copyright © 2016 Accenture All rights reserved. Ian C. Shafer, is a Managing Director in Accenture’s Life Sciences – Accelerated R&D Services (ARDS) practice. In addition to his client delivery responsibilities, Ian leads both the Clinical and Digital practices for ARDS. He has a broad background in clinical development and solution delivery within Biopharma R&D, with a focus on emerging technologies, as well as digital and patient-centric capabilities. Ian graduated from the University of California at Santa Cruz with a BA in Molecular Biology. Nicole Faust Cohen is a Managing Director in Accenture’s Life Sciences Accelerated R&D Services (ARDS) practice. She is the head of both Growth and Strategy and Management Consulting for ARDS globally. Nicole has broad experience in designing and delivering transformation programs for the functional areas of R&D, with great attention to organizational strategy, design and implementation. Nicole graduated from Northwestern University with a B.S. in Biomedical Engineering. Katie M. Strasser, MS, PMP is a Manager in Accenture’s Life Sciences Accelerated R&D Services (ARDS) practices. She has worked across multiple R&D functions at various pharmaceutical companies both within Accenture and in previous work locations. Katie received a B.S. in Kinesiology, Athletic Training from The Pennsylvania State University, a M.S. in Sports Healthcare from the Arizona School of Health Sciences and a Master’s Certificate in Applied Project Management from Villanova University.

15. 15 References 15Copyright © 2016 Accenture All rights reserved. 1. © Portio Research, Mobile Applications Futures 2013-2017, February 2013 2. Accenture and Oracle: Leading the IoT Revolution, 2016: https://www.accenture.com/t20160408T050405__w__/us- en/_acnmedia/PDF-12/Accenture-Oracle-Leading-IoT-Revolution.pdf 3. The Digital Universe of Opportunities: Rich Data and the Increasing Value of the Internet of Things, April 2014: http://www.emc.com/leadership/digital-universe/2014iview/executive- summary.htm 4. http://searchmobilecomputing.techtarget.com/blog/Modern-Mobility/Heres- what-the-future-of-mobile-apps-looks-like 5. Accenture: Industry at a Crossroads: The Rise of Digital in the Outcome- Driven R&D Organization: https://www.accenture.com/us-en/insight- injecting-digital-rd-journey-patient-outcomes