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Anatomy of
Oesophagus
www.entlectures.com
Development of the oesophagus
• At a very early period the
stomach is separated from
pharynx by a mere
constriction from primitive
pharynx. This constriction
is future esophagus.
Source: http://www.nature.com/gimo/contents/pt1/fig_tab/gimo6_F1.html
• Previous to this elongation the
trachea and oesophagus form
a single structure.
• This becomes divided into two
by the in growth of two lateral
septa, which fuse giving rise
to trachea in front and
oesophagus behind.
• At this stage the oesophagus
becomes converted into a
solid rod of cells, losing its
tubular nature.
• This eventually becomes
canalised to form a tube.
Source:
http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=dbio&part
=A3755&rendertype=figure&id=A3755
• Oesophago-tracheal fistula
– Commonest type
– Newborn has violent fits
of vomiting & coughing
on swallowing
– Polyhydraminos
• Partial Obstruction of
Oesophaugs
– Stricture
– Atresia
– newborn salivates
excessively, becomes
cyanotic and vomits
Source: http://www.nature.com/gimo/contents/pt1/fig_tab/gimo6_F10.html
Common Congenital Tracheo-esophageal anomalies
Oesophagus
• A muscular tube; 25 cm in length
– Collapsed at rest,
– Flat in upper 2/3 & rounded in lower 1/3
• Commences at the lower border of the cricoid cartilage.(C6).
• Descends along the front of the spine, through the posterior
mediastinum, passes through the Diaphragm, and, entering
the abdomen, terminates at the cardiac orifice of the stomach,
opposite the eleventh dorsal vertebra.
• In the newborn Upper limit at the level of 4th or 5th CerVertb
and it ends at 9th Dorsal
• Length at birth: 8-10 cm, end of Ist Yr: 12cm,
5th Yr.:16cm 15th: 19cm
• Diameter: Varies whether bolus of food/ fluid
passing thru or not.
– At rest in adults 20 mm but can stretch up
to 30 mm
– At birth it is 5mm at 5 yrs it is 15mm
General direction of the oesophagus is vertical
• Presents two or three slight
curvatures
• At commencement, in the
median line
• Inclines to the left side at the
root of the neck
• Gradually passes to the middle
line
• Again deviates to the left
• The oesophagus also presents an
antero-posterior flexure,
corresponding to the curvature of the
cervical and thoracic portions of the
spine.
• It is the narrowest part of the
alimentary canal, being most
contracted at its commencement,
and at the point where it passes
through the Diaphragm.
Source:
http://www.nature.com/gimo/contents/pt1/fig_tab/gimo6_F5.ht
ml
• In the neck, the oesophagus is in
relation,
– in front, with the trachea; and, at
the lower part of the neck, where it
projects to the left side, with the
thyroid gland and thoracic duct;
– behind, it rests upon the vertebral
column and Longus colli muscle; on
each side, it is in relation with the
common carotid artery (especially
the left, as it inclines to that side),
and part of the lateral lobes of the
thyroid gland; the recurrent
laryngeal nerves ascend between it
and the trachea.
Source: http://www.rvc.ac.uk/Review/SlideBox.cfm
• In the thorax, it is at first situated a
little to the left of the median line: it
passes across the left side of the
transverse part of the aortic arch,
descends in the posterior
mediastinum, along the right side of
the aorta, until near the Diaphragm,
where it passes in front and a little to
the left of this vessel, previous to
entering the abdomen.
Source:
http://en.wikibooks.org/w/index.php?title=File:Gray1032.png&filetimest
amp=20070123212444
Surgical Anatomy
• The relations of the oesophagus are of considerable
practical interest to the surgeon, as he is frequently
required, in cases of stricture of this tube to dilate the
canal by a bougie
• In cases of malignant disease of the oesophagus,, the
greatest care is requisite in directing the bougie through
the strictured part, as a false passage may easily be
made, and the instrument may pass into the
mediastinum, or into one or the other pleural cavity, or
even into the pericardium
• Oesophagus is the narrowest region of
alimentary tract except vermiform appendix.
During its course it has three indentations:
– At 15 cm from incisor teeth is crico-
pharyngues sphincter (normally closed)
(UES)
– At 25 cm aortic arch and left main
bronchus
– At 40 cms where it pierces the
diaphragm where a physiological
sphincter is sited (LES)
Source:
http://www.ispub.com/ispub/ijorl/volume_4_number_2_33/office
_procedure_for_management_of_foreign_body_cricopharynx/b
ody-fig1.jpg
These areas are where most oesophageal foreign
bodies become entrapped.
• The most common site of oesophageal
impaction is at the thoracic inlet
• Defined as the area between the clavicles
on chest radiograph, this is the site of
anatomical change from the skeletal
muscle to the smooth muscle of the
oesophagus. The cricopharyngeus sling at
C6 is also at this level and may "catch" a
foreign body.
• About 70% of blunt foreign bodies that
lodge in the oesophagus do so at this
location.
Source:
www.bhj.org/journal/2001_4303_july01/case_442.htm
• Another 15% become lodged at the mid
oesophagus, in the region where the aortic
arch and carina overlap the oesophagus on
chest radiograph.
• The remaining 15% become lodged at the lower
oesophageal sphincter (LES) at the
gastroesophageal junction.
Source: http://emedicine.medscape.com/article/408752-imaging
The esophagus is a very thin-walled organ, measuring about 2 mm wide
• The oesophageal wall has four
layers: From within outwards:
– Mucous Membrane,
– Sub-mucosa,
– Muscle coat and
– Outer most fibrous layer.
• Unlike other areas of the gut, it does
not have a distinct serosal covering,
but is covered by a thin layer of loose
connective tissue
Source:
http://www.anatomy.tv/StudyGuides/StudyGuide.aspx?g
uideid=15&nextID=19&maxID=0&customer=primal
• Outer longitudinal and inner
circular
• Laimer’s dehiscence/ A
triangular area in the wall of
the pharynx between the
oblique fibres of the inferior
constrictor muscle, and the
transverse fibres of the
cricopharyngeus muscle
through which the Zenker's
diverticulum occurs.
Source:
http://www.nature.com/gimo/contents/
pt1/fig_tab/gimo6_F6.html
Oesophagus divided into functional sphincters
• Upper Oesophageal Sphincter: It is a 2-3 mm zone of elevated
pressure between pharynx & oesophagus. It relates to
cricopharyngeal muscle
• Lower Oesophageal Sphincter: The LES is located at the junction
between the esophagus and stomach, usually localized at or just
below the diaphragmatic hiatus. Despite its distinct physiological
function, it is not easily distinguished anatomically.
Unusual! Arterial supply derived
from vessels feeding mainly other
organs – thyroid, trachea & stomach
Cervical Oesophagus: Right
& Left superior & inferior
thyroid arteries.
Thoracic Oesophagus: Upto
tracheal bifurcation Right &
Left inferior thyroid Artery
direct supply from aorta
(tracheo-bronchial tree)
Abdominal Oesophagus 11
branches off L gastric artery
and Branches of splenic artery
posteriorly
Source:
http://www.nature.com/gimo/contents/pt1/fig_tab/gimo6_F2.html
Venous Relations
• Intra-oesophageal (Intrinsic)
Drainage
– Longitudinally arranged in
Submucosa
– Distal end – portal
anastamoses
• Extra-oesophageal (Extrinsic)
Drainage into locally
corresponding veins
– Inf. thyroid (into
innominate vein),
– Azygos, hemiazygos
– L gastric & splenic
Source: http://www.nature.com/gimo/contents/pt1/fig_tab/gimo6_F3.html
• The venous supply is also segmental.
• From the dense submucosal plexus the venous blood
drains into the superior vena cava. The veins of the
proximal and distal esophagus drain into the azygous
system. Collaterals of the left gastric vein, a branch of
the portal vein, receive venous drainage from the mid-
esophagus.
• The submucosal connections between the portal and
systemic venous systems in the distal esophagus form
esophageal varices in portal hypertension. These
submucosal varices are sources of major hemorrhage in
conditions such as cirrhosis.
• In the proximal third of the esophagus, lymphatics drain
into the deep cervical lymph nodes,
• In the middle third, drainage is into the superior and
posterior mediastinal nodes.
• The distal-third lymphatics follow the left gastric artery
to the gastric and celiac lymph nodes
• There is considerable interconnection
among these three drainage regions.
– Poorly understood
– Important for tumour spread
– Bi-directional spread
– Tracheal bifurcation important landmark
• Of Surgical Interest
– Submucosal lymphatics explain why
tumours may extend long distance
before obstructing lumen
– May also explain high recurrence rates
– Bidirectional lymph flow may explain
retrograde tumour seeding if flow is
blocked
Nerve Supply
• Parasympathetic
– Vagus – motor to muscular coats & secretomotor to glands
• Sympathetic
– From cervical & thoracic sympathetic chain
– Contraction of sphincters, wall relaxation, peristalsis
• Intramural
– Combination of all innervation form plexuses & ganglia
– In muscular layers (myenteric or Auerbach’s plexus)
– In submucosa (Meissner plexus)
Suggested further reading
• Esophagus - anatomy and development ; Braden Kuo, M.D.
and Daniela Urma, M.D.
PART 1 Oral cavity, pharynx and esophagus: GI Motility online
(2006) doi:10.1038/gimo6
http://www.nature.com/gimo/contents/pt1/full/gimo6.html#f10

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Development of the Esophagus

  • 2. Development of the oesophagus • At a very early period the stomach is separated from pharynx by a mere constriction from primitive pharynx. This constriction is future esophagus. Source: http://www.nature.com/gimo/contents/pt1/fig_tab/gimo6_F1.html
  • 3. • Previous to this elongation the trachea and oesophagus form a single structure. • This becomes divided into two by the in growth of two lateral septa, which fuse giving rise to trachea in front and oesophagus behind. • At this stage the oesophagus becomes converted into a solid rod of cells, losing its tubular nature. • This eventually becomes canalised to form a tube. Source: http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=dbio&part =A3755&rendertype=figure&id=A3755
  • 4. • Oesophago-tracheal fistula – Commonest type – Newborn has violent fits of vomiting & coughing on swallowing – Polyhydraminos • Partial Obstruction of Oesophaugs – Stricture – Atresia – newborn salivates excessively, becomes cyanotic and vomits Source: http://www.nature.com/gimo/contents/pt1/fig_tab/gimo6_F10.html Common Congenital Tracheo-esophageal anomalies
  • 5. Oesophagus • A muscular tube; 25 cm in length – Collapsed at rest, – Flat in upper 2/3 & rounded in lower 1/3 • Commences at the lower border of the cricoid cartilage.(C6). • Descends along the front of the spine, through the posterior mediastinum, passes through the Diaphragm, and, entering the abdomen, terminates at the cardiac orifice of the stomach, opposite the eleventh dorsal vertebra. • In the newborn Upper limit at the level of 4th or 5th CerVertb and it ends at 9th Dorsal
  • 6. • Length at birth: 8-10 cm, end of Ist Yr: 12cm, 5th Yr.:16cm 15th: 19cm • Diameter: Varies whether bolus of food/ fluid passing thru or not. – At rest in adults 20 mm but can stretch up to 30 mm – At birth it is 5mm at 5 yrs it is 15mm
  • 7. General direction of the oesophagus is vertical • Presents two or three slight curvatures • At commencement, in the median line • Inclines to the left side at the root of the neck • Gradually passes to the middle line • Again deviates to the left
  • 8. • The oesophagus also presents an antero-posterior flexure, corresponding to the curvature of the cervical and thoracic portions of the spine. • It is the narrowest part of the alimentary canal, being most contracted at its commencement, and at the point where it passes through the Diaphragm. Source: http://www.nature.com/gimo/contents/pt1/fig_tab/gimo6_F5.ht ml
  • 9. • In the neck, the oesophagus is in relation, – in front, with the trachea; and, at the lower part of the neck, where it projects to the left side, with the thyroid gland and thoracic duct; – behind, it rests upon the vertebral column and Longus colli muscle; on each side, it is in relation with the common carotid artery (especially the left, as it inclines to that side), and part of the lateral lobes of the thyroid gland; the recurrent laryngeal nerves ascend between it and the trachea. Source: http://www.rvc.ac.uk/Review/SlideBox.cfm
  • 10. • In the thorax, it is at first situated a little to the left of the median line: it passes across the left side of the transverse part of the aortic arch, descends in the posterior mediastinum, along the right side of the aorta, until near the Diaphragm, where it passes in front and a little to the left of this vessel, previous to entering the abdomen. Source: http://en.wikibooks.org/w/index.php?title=File:Gray1032.png&filetimest amp=20070123212444
  • 11. Surgical Anatomy • The relations of the oesophagus are of considerable practical interest to the surgeon, as he is frequently required, in cases of stricture of this tube to dilate the canal by a bougie • In cases of malignant disease of the oesophagus,, the greatest care is requisite in directing the bougie through the strictured part, as a false passage may easily be made, and the instrument may pass into the mediastinum, or into one or the other pleural cavity, or even into the pericardium
  • 12. • Oesophagus is the narrowest region of alimentary tract except vermiform appendix. During its course it has three indentations: – At 15 cm from incisor teeth is crico- pharyngues sphincter (normally closed) (UES) – At 25 cm aortic arch and left main bronchus – At 40 cms where it pierces the diaphragm where a physiological sphincter is sited (LES) Source: http://www.ispub.com/ispub/ijorl/volume_4_number_2_33/office _procedure_for_management_of_foreign_body_cricopharynx/b ody-fig1.jpg
  • 13. These areas are where most oesophageal foreign bodies become entrapped. • The most common site of oesophageal impaction is at the thoracic inlet • Defined as the area between the clavicles on chest radiograph, this is the site of anatomical change from the skeletal muscle to the smooth muscle of the oesophagus. The cricopharyngeus sling at C6 is also at this level and may "catch" a foreign body. • About 70% of blunt foreign bodies that lodge in the oesophagus do so at this location. Source: www.bhj.org/journal/2001_4303_july01/case_442.htm
  • 14. • Another 15% become lodged at the mid oesophagus, in the region where the aortic arch and carina overlap the oesophagus on chest radiograph. • The remaining 15% become lodged at the lower oesophageal sphincter (LES) at the gastroesophageal junction. Source: http://emedicine.medscape.com/article/408752-imaging
  • 15. The esophagus is a very thin-walled organ, measuring about 2 mm wide • The oesophageal wall has four layers: From within outwards: – Mucous Membrane, – Sub-mucosa, – Muscle coat and – Outer most fibrous layer. • Unlike other areas of the gut, it does not have a distinct serosal covering, but is covered by a thin layer of loose connective tissue Source: http://www.anatomy.tv/StudyGuides/StudyGuide.aspx?g uideid=15&nextID=19&maxID=0&customer=primal
  • 16. • Outer longitudinal and inner circular • Laimer’s dehiscence/ A triangular area in the wall of the pharynx between the oblique fibres of the inferior constrictor muscle, and the transverse fibres of the cricopharyngeus muscle through which the Zenker's diverticulum occurs. Source: http://www.nature.com/gimo/contents/ pt1/fig_tab/gimo6_F6.html
  • 17. Oesophagus divided into functional sphincters • Upper Oesophageal Sphincter: It is a 2-3 mm zone of elevated pressure between pharynx & oesophagus. It relates to cricopharyngeal muscle • Lower Oesophageal Sphincter: The LES is located at the junction between the esophagus and stomach, usually localized at or just below the diaphragmatic hiatus. Despite its distinct physiological function, it is not easily distinguished anatomically.
  • 18. Unusual! Arterial supply derived from vessels feeding mainly other organs – thyroid, trachea & stomach Cervical Oesophagus: Right & Left superior & inferior thyroid arteries. Thoracic Oesophagus: Upto tracheal bifurcation Right & Left inferior thyroid Artery direct supply from aorta (tracheo-bronchial tree) Abdominal Oesophagus 11 branches off L gastric artery and Branches of splenic artery posteriorly Source: http://www.nature.com/gimo/contents/pt1/fig_tab/gimo6_F2.html
  • 19. Venous Relations • Intra-oesophageal (Intrinsic) Drainage – Longitudinally arranged in Submucosa – Distal end – portal anastamoses • Extra-oesophageal (Extrinsic) Drainage into locally corresponding veins – Inf. thyroid (into innominate vein), – Azygos, hemiazygos – L gastric & splenic Source: http://www.nature.com/gimo/contents/pt1/fig_tab/gimo6_F3.html
  • 20. • The venous supply is also segmental. • From the dense submucosal plexus the venous blood drains into the superior vena cava. The veins of the proximal and distal esophagus drain into the azygous system. Collaterals of the left gastric vein, a branch of the portal vein, receive venous drainage from the mid- esophagus. • The submucosal connections between the portal and systemic venous systems in the distal esophagus form esophageal varices in portal hypertension. These submucosal varices are sources of major hemorrhage in conditions such as cirrhosis.
  • 21. • In the proximal third of the esophagus, lymphatics drain into the deep cervical lymph nodes, • In the middle third, drainage is into the superior and posterior mediastinal nodes. • The distal-third lymphatics follow the left gastric artery to the gastric and celiac lymph nodes
  • 22. • There is considerable interconnection among these three drainage regions. – Poorly understood – Important for tumour spread – Bi-directional spread – Tracheal bifurcation important landmark • Of Surgical Interest – Submucosal lymphatics explain why tumours may extend long distance before obstructing lumen – May also explain high recurrence rates – Bidirectional lymph flow may explain retrograde tumour seeding if flow is blocked
  • 23. Nerve Supply • Parasympathetic – Vagus – motor to muscular coats & secretomotor to glands • Sympathetic – From cervical & thoracic sympathetic chain – Contraction of sphincters, wall relaxation, peristalsis • Intramural – Combination of all innervation form plexuses & ganglia – In muscular layers (myenteric or Auerbach’s plexus) – In submucosa (Meissner plexus)
  • 24. Suggested further reading • Esophagus - anatomy and development ; Braden Kuo, M.D. and Daniela Urma, M.D. PART 1 Oral cavity, pharynx and esophagus: GI Motility online (2006) doi:10.1038/gimo6 http://www.nature.com/gimo/contents/pt1/full/gimo6.html#f10