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Drugs and their antidotes

about the antidotes of some common drugs which are essential for pharmacists , nurses and doctors to know

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Drugs and their antidotes

  1. 1. Drugs and their Antidotes The need of antidotes for different drugs happened due to the toxicology of drugs or we may say that due to the misuse of drugs. Toxicology: The study of the effect of poisons on the function of living systems "All things are poison and nothing is without poison, only the dose permits something not to be poisonous." Paracelsus (1493-1541) ‘Grandfather of Toxicology’ Therapeutic effect Increasing Dose Toxic effect List of common drugs and their Antidotes Name of Drug Antidote 1. Acetaminophen Acetylcycteine 2. Curare Tensilon 3. coumadin Vita K 4. Digitalis Digibind 5. Cyanide poisoning Methylene blue 6. Benzodiazepine Flumazenil 7. Iron Desferal 8. Lead EDTA , BAL 9. Ethylene poisoning Antizol 10. Magnesium sulphate Calcium gluconate 11. Penicillin Epinephrine 12. Morphine sulphate Naloxone hydrochloride 13. Vincristine Hyaluronidase 14. Neostigmine Pralidoxime chloride 15. Mestinon Atropine sulfate 16. Ethylene glycol Ethanol 17. Caffeine Esmolol 18. Beta blockers Glucagon 19. Barbiturates Charcoal 20. Meyaproterenol Esnolol 21. Cholinesterase inhibitors Atropine 22. Heparine Protamine sulfate 23. Isoniazid Vita b6 24. Iron salts Deferoxamine 1
  2. 2. 25. Warfarin Vita K 26. Salicylates Charcoal 27. Quinidine Sodium bicarbonate 28. Muscarinic receptor blockers Physostigmine 29. Calcium channel blockers Glucagon 30. Cyclophosphamide MESNA 31. Dopamine Phentolamie 32. Fluorouracil Leucoverin calcium 33. Insuline inj Glucose 34. Methotrexate Leucovorine calcium 35. Tricyclic antidepressants Phyostigmine 36. Potassium Insuline and glucose 37. Chloroqunine Diazepam 38. Amphetamine Propranolol 39. Arsenic Dimercaprol 40. Carbamate Atropine 41. MAOI Phentolamine References  The antidote inside the world of new pharma by Barry Werth (2014)  Text book of pharmacology by Lipponcott  Antidotes Principles and Clinical Applications by Robert Flanagan (2003)  Medical toxicology by Richerd C. Dart (2004) 2

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