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Influenza 2009 With Sound

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Influenza 2009 With Sound

  1. 1. INFLUENZA 2009 <ul><li>Seasonal Flu </li></ul><ul><li>A/Brisbane/59/2007 (H1N1) </li></ul><ul><li>A/Uruguay/716/2007 (H3N2) </li></ul><ul><li>B/Brisbane/60/2008 </li></ul><ul><li>H1N1 “Swine” Flu </li></ul><ul><li>Influenza A 2009 H1N1 A / Mexico / 001 / 2009 (H1N1) </li></ul><ul><li>Jim Gervase, R.Ph., </li></ul><ul><li>Director of Pharmacy, Corry Memorial Hospital, Corry, Pa </li></ul><ul><li>October, 2009 </li></ul>
  2. 2. Outline For Today <ul><li>What is Influenza ? </li></ul><ul><li>Why is it important to us? </li></ul><ul><li>History of Influenza </li></ul><ul><li>2009-2010 Seasonal Influenza </li></ul><ul><li>Influenza A 2009 H1N1 A / Mexico / 001 / 2009 (H1N1) </li></ul><ul><li>Vaccines </li></ul><ul><li>Antivirals </li></ul>
  3. 3. What is Influenza <ul><li>Virus </li></ul><ul><li>Unpredictable </li></ul><ul><li>Most strains evolve constantly (drift) </li></ul><ul><li>Very Contagious </li></ul>
  4. 4. What is Influenza <ul><li>PATHOGENISIS </li></ul><ul><li>Transmitted in Respiratory Secretions </li></ul><ul><li>Replicates in the Endothelium of the Respiratory Tract </li></ul><ul><li>Causes Cell Destruction </li></ul><ul><li>Viral Shedding begins on contact and continues for 10 days </li></ul>
  5. 5. What is Influenza <ul><li>CLINICAL FEATURES </li></ul><ul><li>Incubation Period 1 to 4 Days </li></ul><ul><li>Severity of Illness depends on Prior Exposure to Same or Similar Strain </li></ul><ul><li>Onset of Symptoms is Abrupt: Nonproductive Cough, Fever, Muscle Aches, Sore Throat, Headache </li></ul>
  6. 6. What is Influenza <ul><li>INFLUENZA VIRUS STRAINS </li></ul><ul><li>Type A Moderate to severe symptoms </li></ul><ul><li>All age groups </li></ul><ul><li>Affects humans and animals </li></ul><ul><li>Type B Milder Disease </li></ul><ul><li>Primarily Affects Children </li></ul><ul><li>Humans Only </li></ul><ul><li>Type C Rare reports in Humans </li></ul>
  7. 8. What Is NOT Influenza? <ul><li>Colds and other Viruses </li></ul><ul><li>low fever or no fever, productive cough, feel sick but ABLE to function </li></ul><ul><li>Bronchitis / COPD / Pneumonia </li></ul><ul><li>Smoking, predisposition, immune compromised </li></ul><ul><li>GI “flu” </li></ul><ul><li>Often caused by Bacteria due to Food Poisoning </li></ul><ul><li>May be caused by other viruses </li></ul>
  8. 9. WHY IS FLU IMPORTANT TO US ? <ul><li>We Feel Awful </li></ul><ul><li>We Miss Work </li></ul><ul><li>We Infect Our Loved Ones </li></ul><ul><li>We Infect the Community Around Us </li></ul><ul><li>They Feel Awful </li></ul><ul><li>They Miss Work </li></ul><ul><li>…………………… Some will be Hospitalized </li></ul><ul><li>… .. ……………………..Some will Die </li></ul>
  9. 10. THE HISTORY OF INFLUENZA <ul><li>First World Wide Pandemic was in 1580 </li></ul><ul><li>There were at least 4 pandemics in the 19 th Century </li></ul><ul><li>Pandemic of 1918 Killed 21 Million People </li></ul>
  10. 11. 2009-2010 Seasonal Influenza Vaccine <ul><li>A/Uruguay/716/2007 (H3N2) </li></ul><ul><li>B/Brisbane/60/2008 </li></ul><ul><li>A/Brisbane/59/2007 (H1N1) </li></ul><ul><li>Mismatch of Vaccine to Circulating Viruses </li></ul><ul><li>197 Flu Viruses Circulating </li></ul><ul><li>New substrain has emerged </li></ul><ul><li>A/Brisbane/01/2009 (H3N2) From A/Brisbane/10/2007 (H3N2) (drift) </li></ul>
  11. 12. 2009-2010 Seasonal Influenza <ul><li>Has JUST STARTED to be seen in the United States in large numbers . </li></ul><ul><li>80 to 90 % of all Type A Influenza is “Swine” Flu at this time. </li></ul><ul><li>October 12, 2009 </li></ul>
  12. 13. Influenza A 2009 H1N1 A / Mexico / 001 / 2009 (H1N1) (Swine Flu) <ul><li>Symptoms </li></ul><ul><li>Prevalence </li></ul><ul><li>How to prevent it’s spread </li></ul><ul><li>When do you call the Doc? </li></ul><ul><li>Family Preparedness </li></ul>
  13. 14. <ul><li>. </li></ul>Influenza A 2009 H1N1 A / Mexico / 001 / 2009 (H1N1) Symptoms
  14. 15. Influenza A 2009 H1N1 A / Mexico / 001 / 2009 (H1N1) Prevalence Pandemic influenza A/H1N1 08-09 seasonal influenza
  15. 16. 2009-2010 Seasonal Influenza <ul><li>A/Brisbane/59/2007 (H1N1) </li></ul><ul><li>A/Uruguay/716/2007 (H3N2) </li></ul><ul><li>B/Brisbane/60/2008 </li></ul><ul><li>Possible Mismatch of Vaccine to Circulating Viruses Circulating in Early 2009 </li></ul><ul><li>197 Flu Viruses Circulating </li></ul><ul><li>New substrain has emerged A/Brisbane (H3N2) From A/Brisbane/10/2007 (H3N2) (drift) </li></ul>
  16. 17. Influenza A 2009 H1N1 A / Mexico / 001 / 2009 (H1N1) Distribution
  17. 18. Influenza A 2009 H1N1 A / Mexico / 001 / 2009 (H1N1)
  18. 20. Influenza A 2009 H1N1 A / Mexico / 001 / 2009 (H1N1) USE OF ANTIVIRALS <ul><li>Tamiflu and Relenza only. </li></ul><ul><li>May decrease duration and severity of illness. </li></ul><ul><li>Must be given within the first 24 – 48 hrs. </li></ul><ul><li>Seasonal Influenza has shown some resistance to antivirals. Swine Flu has now demonstrated rare resistance. </li></ul>
  19. 21. Influenza A 2009 H1N1 A / Mexico / 001 / 2009 (H1N1) <ul><li>. </li></ul>
  20. 22. Influenza A 2009 H1N1 A / Mexico / 001 / 2009 (H1N1) <ul><li>. </li></ul>
  21. 24. Influenza A 2009 H1N1 A / Mexico / 001 / 2009 (H1N1)
  22. 25. Influenza A 2009 H1N1 A / Mexico / 001 / 2009 (H1N1) <ul><li>. </li></ul>
  23. 26. Influenza A 2009 H1N1 A / Mexico / 001 / 2009 (H1N1) <ul><li>. </li></ul>
  24. 32. SHOULD I GET THE SWINE FLU VACCINE ? (Non Healthcare Worker) <ul><li>1. I SHOULD GET IT TO PROTECT MY LOVED ONES. </li></ul><ul><li>2. I SHOULD GET IT SO THAT I CAN TAKE CARE OF MY LOVED ONES IF THEY GET SICK. </li></ul><ul><li>3. I SHOULD GET IT SO THAT I DON’T MISS WORK. </li></ul><ul><li>4. I SHOULD GET IT BECAUSE I AM AT HIGH RISK OF COMPLICATIONS </li></ul>
  25. 33. SHOULD I GET THE SWINE FLU VACCINE ? ( Healthcare Worker) <ul><li>1. I SHOULD GET IT TO PROTECT MY LOVED ONES. </li></ul><ul><li>2. I SHOULD GET IT SO THAT I CAN TAKE CARE OF MY PATIENTS WHO HAVE IT. </li></ul><ul><li>3. I SHOULD GET IT SO THAT I DON’T MISS WORK. </li></ul><ul><li>4. I SHOULD GET IT SO THAT I DON’T CARRY IT HOME TO MY LOVED ONES. </li></ul><ul><li>5. I SHOULD GET IT BECAUSE IT IS MY DUTY. </li></ul>
  26. 34. SHOULD I GET THE SWINE FLU VACCINE ? ( Healthcare Worker)

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