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i3 Consult
Integrated Intelligence for Healthcare Industries
WALLACE M. MACINDOE PhD MBA
Founder & Principal Consultant
4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 2
i3 Consult- Our Vision
i3 Consult is an information-based consulting, integration and IT outsourcing service entity
committed to providing premium strategic marketing, financial and operational management
solutions for healthcare, pharmaceutical and other life science organisations.
4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 3
•Healthcare, pharmaceutical and the life science industries are influenced by a myriad of
different stakeholders as well as by various political and socio-economic factors – see the Pestle
Analysis, next slide
•We assist the client in gaining a “360°” view of themselves and in combination with the “bird's
eye” view which we have of the healthcare & life science industry, we propose a strategy of
success.
i3 Consult- Our Rationale
4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 4
i3 Consult- Healthcare Pestle Analysis
4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 5
i3 Consult- Our Value Add by Value Chain
Analysis
•We identify key activities within (e.g. bulk material procurement) and around (e.g. raising
pharmaceutical sales levels via innovative web based interfaces) your organization and propose
synergy with the competitive strength(s) of your healthcare product or service.
4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 6
•Registered products nearing the end of their lifecycle can be low cost “recovery” candidates for
other clinical indications or as an orphan drug.
•Orphan drugs may help pharma companies to lessen the impact of revenue short-falls caused
by patent expiries of blockbuster drugs.
•Orphan drugs could offer a strategy for pharma companies to develop new areas of treatment
and improved patient outcomes.
Pharm Bioallied Sci. 2010 Oct-Dec; 2(4): 290–299
i3 Consult- Our Value Add – Drug Recovery
4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 7
•We monitor your drug development strategy (DDS) to include all the necessary study designs,
confirming the status of principal investigators involved, as well as inclusion of sufficiently robust
statistical analyses along with realistic timelines.
•An element of contingency planning and risk management needs to be identified in the DDS.
•In assessing risks for adverse events and issues of concern in a clinical trial, not every risk carries
equal significance. By Pareto's Principle of the 80-20 rule, select the top risks that pose the highest
potential for failure in your clinical trial and focus your monitoring and risk planning activities on
those items.
•Equally however, don’t ignore the other factors but just spread the focus proportionately
i3 Consult- Our Value Add – Drug Development
4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 8
•Other success critical issues we consider:
I. Protection of intellectual property – beyond NCE patent protection (PP), follow up
with PP on processes as well; also there should be no time lag for registration of
trade marks regardless of whether they are products or processes.
II. Reimbursement – investigation of the following in proposing reimbursement:
a) pricing of any competing NCEs, generics or pharmacoequivalents
b) launch sequence particularly if there is multiple indication potential
c) new government policies across multiple markets and reimbursement trends
d) influence of key opinion leaders, investigators and patient advocacy groups
i3 Consult- Our Value Add – Drug Development
4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 9
•Review SOPs to maximise cost effectiveness and compliance with green chemistry processes –
see our report Sustainability Metrics for Pharmaceutical Manufacturing
(www.i3consult.com/i3shop/)
•Monitor and re-negotiate supply manufacturing contracts so as to meet your organisation's
standards thus streamlining inefficient customer interfaces
•Integrate JIT and high end technology factory processes and synchronise with highly variable
customer supply orders
•Propose post-marketing services so as to expand the value chain
i3 Consult- Our Value Add – Manufacturing
4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 10
•To adapt to ever changing customer and market needs, the distribution strategy
needs to be monitored and reviewed for cost effectiveness and for it's impact on sales
•Further points of consideration for the distribution strategy:
–Feasibility of emerging markets with high potential beyond logistics challenges
–Speed-to-market for NCE launches
–Response time for recalls and demand spikes
–Opt for the outsourcing advantage since they offer a proven business model and
process
i3 Consult- Our Value Add – Distribution
4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 11
•Power of the Internet has led to a far more patient-centric market and therefore your marketing
message needs to focus on the patient rather than the product
•Doctors are always busy, inundated with clinical information, so formulate content that
addresses their questions specifically meeting their information needs.
•Use technology that enables content and messaging to be edited according to the patient and
physician needs but also have built-in compliance workflows.
•Develop your closed loop marketing (CLM) tool so that your sales rep. finds it a seamless tool for
their particular patient or physician marketing channel and check for compliance with company
marketing objectives.
•Review sales or marketing data periodically to formulate an action plan for improved sales
revenues
i3 Consult- Our Value Add – Sales & Marketing
4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 12
•Life Cycle Analysis (LCA) : Whether your launch is still under post marketing surveillance or you’re
seeking to extend an existing therapeutic line, we will assess whether your chosen strategy is
appropriate given the stage of the product’s lifecycle and those of competitors in the same
therapeutic class.
i3 Consult- Life Cycle Analysis
Here is shown an example of LCA from the Asian
generics market.
4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 13
•Different countries have different pharmacoeconomic systems for evaluating the efficient use of
healthcare resources, here we clarify the profitability of your chosen market through frameworks
such as Porter’s Five Forces, McKinsey’s 7Ss, BCG Analysis, Strategic Clocking and other in-house
models.
i3 Consult- Framework Approach
4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 14
•Corporate Profiling using Financial Ratios, e.g. Current Asset Turnover Rates (Sales/Total Current
Assets), Acid Test Ratios (Cash/Current Liabilities) & Capital Gearing Ratios (Debt Capital/Capital
Interests) to harvest, hold, grow, turnaround or find niche with your current product portfolio.
•Product and R&D Investment Appraisal in terms of Net Present Value and Internal Rate of Return.
i3 Consult- Financial Management Services
4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 15
•Unlike the blue chip consulting firms, our fees are very competitively priced and are based on
the deliverables you specifically require.
•Our deliverables are from dedicated specialists and experts in the healthcare and life science
industry rather than from new graduates and mid-career hires of the big consulting firms.
•We do not charge by the hour but more by the scope and critical need of the consultancy
required.
i3 Consult- Our Deliverables & Fees
Please enquire within and we promise to be a listening ear to your
affordability!
www.i3consult.com
wallace.macindoe@i3consult.com

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i3 Consult - Solutions for Pharma, Provider & Patient

  • 1. i3 Consult Integrated Intelligence for Healthcare Industries WALLACE M. MACINDOE PhD MBA Founder & Principal Consultant
  • 2. 4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 2 i3 Consult- Our Vision i3 Consult is an information-based consulting, integration and IT outsourcing service entity committed to providing premium strategic marketing, financial and operational management solutions for healthcare, pharmaceutical and other life science organisations.
  • 3. 4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 3 •Healthcare, pharmaceutical and the life science industries are influenced by a myriad of different stakeholders as well as by various political and socio-economic factors – see the Pestle Analysis, next slide •We assist the client in gaining a “360°” view of themselves and in combination with the “bird's eye” view which we have of the healthcare & life science industry, we propose a strategy of success. i3 Consult- Our Rationale
  • 4. 4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 4 i3 Consult- Healthcare Pestle Analysis
  • 5. 4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 5 i3 Consult- Our Value Add by Value Chain Analysis •We identify key activities within (e.g. bulk material procurement) and around (e.g. raising pharmaceutical sales levels via innovative web based interfaces) your organization and propose synergy with the competitive strength(s) of your healthcare product or service.
  • 6. 4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 6 •Registered products nearing the end of their lifecycle can be low cost “recovery” candidates for other clinical indications or as an orphan drug. •Orphan drugs may help pharma companies to lessen the impact of revenue short-falls caused by patent expiries of blockbuster drugs. •Orphan drugs could offer a strategy for pharma companies to develop new areas of treatment and improved patient outcomes. Pharm Bioallied Sci. 2010 Oct-Dec; 2(4): 290–299 i3 Consult- Our Value Add – Drug Recovery
  • 7. 4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 7 •We monitor your drug development strategy (DDS) to include all the necessary study designs, confirming the status of principal investigators involved, as well as inclusion of sufficiently robust statistical analyses along with realistic timelines. •An element of contingency planning and risk management needs to be identified in the DDS. •In assessing risks for adverse events and issues of concern in a clinical trial, not every risk carries equal significance. By Pareto's Principle of the 80-20 rule, select the top risks that pose the highest potential for failure in your clinical trial and focus your monitoring and risk planning activities on those items. •Equally however, don’t ignore the other factors but just spread the focus proportionately i3 Consult- Our Value Add – Drug Development
  • 8. 4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 8 •Other success critical issues we consider: I. Protection of intellectual property – beyond NCE patent protection (PP), follow up with PP on processes as well; also there should be no time lag for registration of trade marks regardless of whether they are products or processes. II. Reimbursement – investigation of the following in proposing reimbursement: a) pricing of any competing NCEs, generics or pharmacoequivalents b) launch sequence particularly if there is multiple indication potential c) new government policies across multiple markets and reimbursement trends d) influence of key opinion leaders, investigators and patient advocacy groups i3 Consult- Our Value Add – Drug Development
  • 9. 4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 9 •Review SOPs to maximise cost effectiveness and compliance with green chemistry processes – see our report Sustainability Metrics for Pharmaceutical Manufacturing (www.i3consult.com/i3shop/) •Monitor and re-negotiate supply manufacturing contracts so as to meet your organisation's standards thus streamlining inefficient customer interfaces •Integrate JIT and high end technology factory processes and synchronise with highly variable customer supply orders •Propose post-marketing services so as to expand the value chain i3 Consult- Our Value Add – Manufacturing
  • 10. 4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 10 •To adapt to ever changing customer and market needs, the distribution strategy needs to be monitored and reviewed for cost effectiveness and for it's impact on sales •Further points of consideration for the distribution strategy: –Feasibility of emerging markets with high potential beyond logistics challenges –Speed-to-market for NCE launches –Response time for recalls and demand spikes –Opt for the outsourcing advantage since they offer a proven business model and process i3 Consult- Our Value Add – Distribution
  • 11. 4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 11 •Power of the Internet has led to a far more patient-centric market and therefore your marketing message needs to focus on the patient rather than the product •Doctors are always busy, inundated with clinical information, so formulate content that addresses their questions specifically meeting their information needs. •Use technology that enables content and messaging to be edited according to the patient and physician needs but also have built-in compliance workflows. •Develop your closed loop marketing (CLM) tool so that your sales rep. finds it a seamless tool for their particular patient or physician marketing channel and check for compliance with company marketing objectives. •Review sales or marketing data periodically to formulate an action plan for improved sales revenues i3 Consult- Our Value Add – Sales & Marketing
  • 12. 4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 12 •Life Cycle Analysis (LCA) : Whether your launch is still under post marketing surveillance or you’re seeking to extend an existing therapeutic line, we will assess whether your chosen strategy is appropriate given the stage of the product’s lifecycle and those of competitors in the same therapeutic class. i3 Consult- Life Cycle Analysis Here is shown an example of LCA from the Asian generics market.
  • 13. 4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 13 •Different countries have different pharmacoeconomic systems for evaluating the efficient use of healthcare resources, here we clarify the profitability of your chosen market through frameworks such as Porter’s Five Forces, McKinsey’s 7Ss, BCG Analysis, Strategic Clocking and other in-house models. i3 Consult- Framework Approach
  • 14. 4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 14 •Corporate Profiling using Financial Ratios, e.g. Current Asset Turnover Rates (Sales/Total Current Assets), Acid Test Ratios (Cash/Current Liabilities) & Capital Gearing Ratios (Debt Capital/Capital Interests) to harvest, hold, grow, turnaround or find niche with your current product portfolio. •Product and R&D Investment Appraisal in terms of Net Present Value and Internal Rate of Return. i3 Consult- Financial Management Services
  • 15. 4/25/2017INTEGRATED INTELLIGENCE FOR HEALTHCARE INDUSTRIES 15 •Unlike the blue chip consulting firms, our fees are very competitively priced and are based on the deliverables you specifically require. •Our deliverables are from dedicated specialists and experts in the healthcare and life science industry rather than from new graduates and mid-career hires of the big consulting firms. •We do not charge by the hour but more by the scope and critical need of the consultancy required. i3 Consult- Our Deliverables & Fees Please enquire within and we promise to be a listening ear to your affordability! www.i3consult.com wallace.macindoe@i3consult.com