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  1. 1. THROMBOCYTOPENIAMónica Delgado C.
  2. 2.  The terms thrombocytopenia refer to a relativedecrease of platelets in blood.
  3. 3. CAUSES Vitamin B12 or folic acid deficiency Idiopathic thrombocytopenic purpura Thrombocytopenia-inducing medications Increased destruction Decreased production of thrombopoietin by the liverin liver failure Leukemia or myelodysplastic syndrome
  4. 4. SIGNS AND SYMPTOMS Occasionally, there may bebruising , particularlypurpura in the forearms,petechia (pinpointhemorrhages on skin andmucous membranes),nosebleeds and/orbleeding gumsA person with this disease mayalso complain of malaise, fatigue,and general weakness (with orwithout accompanying bloodloss).
  5. 5. DIAGNOSIS Laboratory tests might include: full blood count liver enzymes renal function vitamin B12 levels folic acid levels erythrocyte sedimentation rate peripheral blood smear
  6. 6. TREATMENT The main concept in treating thrombocytopenia is toeliminate the underlying problem, whether thatmeans discontinuing suspected drugs that causethrombocytopenia, or treating underlying sepsis.
  7. 7.  Thrombocytopenia affects a few percent ofnewborns, and its prevalence in neonatal intensivecare units is high. Most of the cases of thrombocytopenia affectpreterm birth infants and are results of placentalinsufficiency and/or fetal hypoxia.