CHECKED BY: PRESENTED BY:
DR. NEHA MAHAJAN DR. VIRSHALI GUPTA
DISORDERS OF CONNECTIVE TISSUE
WHAT IS CONNECTIVE
Connective tissue is the group of tissues
that fills the interstices b/w more
specialised elements & serves to hold
them together & support them.
BY- ‘’GP PAL 3rd edition’’
Defined as that group of tissues
predominantly composed of intercellular
matrix , secreted mainly by its cells
which are therefore , usually widely
BY – ‘’HAMS 9th edition’’ 4
FIBERS OF CONNECTIVE
2-10nm 0.5 -2µm 0.1-2µm 0.2-1.5µm
LOCATION Walls of blood
dentin & pulp
COURSE Run in bundles
Run singly &
White fibers Argyrophilic
Yellow fibers -------
MAIN CHARACTERISTICS OF DIFFERENT
1 DERMIS, BONE,
11 HYALNE AND
CHONDROBLAST RESISTANCE TO
111 SMOOTH MUSCLE,
KIDNEY , LUNG, PDL,
1V EPITHELIAL AND
V MUSCLE BASAL ----- ----- 10
CELL TYPE MAIN PRODUCT OR
PRODUCTION OF FIBERS AND
PLASMA CELL PRODUCTION OF
LYMPHOCYTE PRODUCTION OF IMMUNE
PHAGOCYTOSIS OF FOREIGN
MAST CELL, BASOPHIL LIBERATION OF
ADIPOSE CELL STORAGE OF NEUTRAL FATS ENERGY RESERVOIR,
DIAGRAM SHOWING CELLS AND
FIBRES OF CONNECTIVE FIBERS
Occupies the space b/w the cells & fibers.
The enzyme hyaluronidase increase the fluidity of
These are responsible for physical properties
of ground substance.
Granular in appearance.
Consistency: varies, fluid to gel.
CLASSIFICATION OF CONNECTIVE
CONNECTIVE TISSUE PROPER
A. EMBRYONAL CT
B. REGULAR CT
i. Loose CT
ii. Dense CT
C. SPECIAL FORMS
i . Elastic
A. FLUID CT
It consist of two varieties 1.mesenchymal and 2.
Present for most of the parts during embryonic and
When present post- natally , associated with healing
of injured tissue or tumorous lesion.
Made up of small cells with slender branching
processes that join to form a fine network.
Type of connective tissue composed of special cells
known as chondrocytes along with collagen or
yellow elastic fibers.
COMPACT BONE SPONGY BONE
OTHER NAME CORTICAL BONE TRABECULAE BONE
DENSITY COMPACT POROUS
LOCATION OUTER BONE INNER BONE
FUNCTIONAL UNIT OSTEON TRABECULAE
FUNCTIONS OF CONNECTIVE TISSUE
SUPPORT- To epithelium e.g.: lamina propria.
STRENGTH- Provides tensile strength to
mechanical stress e.g.: dermis of skin , ligament.
STORAGE- Fat cells store fat while ground
substance store water , ions and inorganic
TRANSPORT- Water, ions and inorganic materials
are transported from blood to various tissues of
body through connective tissue matrix.
PACKING- They fill spaces e.g.: loose connective
tissue and adipose tissue.
REPAIR- Helps in wound healing
DEFENSE- Cells helps in defense action e.g.:
plasma cells, macrophages, lymphocytes,
The gingival connective tissue provides strength to
gums and make the gums to cement root and alveolar
The dense gingival connective tissue is referred to as a
Consists of 2 layers:
Papillary layer reticular layer
HOW EPITHELIUM CONNECTS WITH
CONNECTIVE TISSUE ??
24STRUCTURE OF BASEMENT MEMBRANE
DISORDERS OF CONNECTIVE TISSUE
MARFAN’S SYNDROME –
Deficiency of vitamin C
Bleeding gums, loosening of teeth with grade 1 – 2
mobility , gingivitis n sometimes bluish
EHLERS- DANLOS SYNDROME
Difficulty in opening mouth due to involvement of
Blisters in mouth which erupts later.
Blisters are painful, but don’t itch.
Difficulty in swallowing.
Basic tissue of the body.
Includes fat, cartilage, bone and blood.
Provides support, fills the spaces between
organs, protecting organs and aiding in the
transport of materials around the body.
Textbook of histology GP Pal 3rd edition.
Textbook of human histology 3rd edition by Inderbir
Tencate’s oral histology.
Ham’s histology 9th edition by David.
Textbook of oral histology & embryology (orban’s) 12th
edition by GS Kumar.
Textbook of oral histology by D.Vincent Provenza 2nd