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-The disease is caused by a virus called Newcastle Disease
Virus (NDV)
-Virus classification :
+ Negative single strand RN...
- Virus strains :
+ Lentogenic NDV
+ Mesogenic NDV
+ Velogenic NDV (The strongest strain )
- It is a pantropic virus which...
Transmission occurs by exposure to faecal
and other excretions from infected birds, and
through contact with contaminated
...
-Newcastle disease is a contagious bird disease affecting
many domestic and wild avian species; it is transmissible to
hum...
Field diagnosis

Clinical
symptoms

Laboratory diagnosis

Post-mortem
symptoms
+ It depend on the strain of the NDV , health , age
and species of the poultry

+ It includes respiratory and nervous symp...
1-Gasping
2-Coughing
swelling of the tissues around the eyes
and neck
Watery greenish diarrhea

Normal

Feaces in case of
diarrhea
-Reduce in egg production
-Thin egg shell
-Sudden death
-Multifocal petechial hemorrhage in
The trachea (mild hemorrhage)
-Pulmonary congestion and edema
-Edema and petechial hemorrhage
in proventriculus

proventriculus

Gizzard
-Hemorrhage in the whole intestine
-Hemorrhage in liver
Normal liver
1-Serological tests:
ELISA- FAT – HI
2-Detection of virus nucleic acid:
PCR-Hybridization
3-Isolation of the virus:
Tissue...
samples are obtained by swabbing the
trachea and the cloaca. Cotton swabs can
be used. The virus can also be isolated from...
Any animals showing symptoms of
Newcastle disease should be quarantined
immediately. New birds should also be
vaccinated b...
Newcastle disease
Newcastle disease
Newcastle disease
Newcastle disease
Newcastle disease
Newcastle disease
Newcastle disease
Newcastle disease
Newcastle disease
Newcastle disease
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Newcastle disease

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Newcastle disease

  1. 1. -The disease is caused by a virus called Newcastle Disease Virus (NDV) -Virus classification : + Negative single strand RNA virus + Order : Mononegaveralis + Famiy : Paramyxoviridae + Genus: Avulavirus + Species : Newcastle disease virus (NDV)
  2. 2. - Virus strains : + Lentogenic NDV + Mesogenic NDV + Velogenic NDV (The strongest strain ) - It is a pantropic virus which has more than one tropism ( Nervous system and respiratory system )
  3. 3. Transmission occurs by exposure to faecal and other excretions from infected birds, and through contact with contaminated food, water, equipment and clothing. High concentrations of the NDV are found in birds' bodily discharges; therefore, the disease can be spread easily by mechanical means. Virus-bearing material can be picked up on shoes and clothing and carried from an infected flock to a healthy one.
  4. 4. -Newcastle disease is a contagious bird disease affecting many domestic and wild avian species; it is transmissible to humans. Its effects are most notable in domestic poultry due to their high susceptibility and the potential for severe impacts of an epizootic on the poultry industries. It is endemic to many countries. Exposure of humans to infected birds (for example in poultry processing plants) can cause mild conjunctivitis and influenza-like symptoms, but the Newcastle disease virus (NDV) otherwise poses no hazard to human health. Interest in the use of NDV as an anticancer agent has arisen from the ability of NDV to selectively kill human tumour cells with limited toxicity to normal cells.
  5. 5. Field diagnosis Clinical symptoms Laboratory diagnosis Post-mortem symptoms
  6. 6. + It depend on the strain of the NDV , health , age and species of the poultry + It includes respiratory and nervous symptoms +The incubation period for the disease ranges from two to 15 days
  7. 7. 1-Gasping 2-Coughing
  8. 8. swelling of the tissues around the eyes and neck
  9. 9. Watery greenish diarrhea Normal Feaces in case of diarrhea
  10. 10. -Reduce in egg production -Thin egg shell
  11. 11. -Sudden death
  12. 12. -Multifocal petechial hemorrhage in The trachea (mild hemorrhage)
  13. 13. -Pulmonary congestion and edema
  14. 14. -Edema and petechial hemorrhage in proventriculus proventriculus Gizzard
  15. 15. -Hemorrhage in the whole intestine
  16. 16. -Hemorrhage in liver Normal liver
  17. 17. 1-Serological tests: ELISA- FAT – HI 2-Detection of virus nucleic acid: PCR-Hybridization 3-Isolation of the virus: Tissue culture –Embryonic Chicken Egg
  18. 18. samples are obtained by swabbing the trachea and the cloaca. Cotton swabs can be used. The virus can also be isolated from the lungs, brain, spleen, liver, and kidneys.
  19. 19. Any animals showing symptoms of Newcastle disease should be quarantined immediately. New birds should also be vaccinated before being introduced to a flock. An inactivated viral vaccine is available, as well as various combination vaccines. Antibiotic can be given to prevent bacterial infection.

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