Successfully reported this slideshow.
We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. You can change your ad preferences anytime.
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
Template Innovation Day presentationCONFIDENTIAL
FUJIRE...
2
Frederik Mortier
Consultant Applied Physics & Systems 2012- now
Researcher @ Ghent University 2011-2012
MSc. in Engineer...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
3
CONFIDENTIAL
1
2
3
4
5
CONTENT
Introduction Fujirebio...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
CONFIDENTIAL
4
Fujirebio
Company introduction
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
5
CONFIDENTIAL
Introduction
Fujirebio Europe N.V.
• Hea...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
6
CONFIDENTIAL
Introduction
IVD testing solution: assay...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
CONFIDENTIAL
7
Business case
TENDIGO™ assay processor
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
8
CONFIDENTIAL
Business case
Business model Fujirebio ...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
9
CONFIDENTIAL
Business case
How to define the perfect ...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
CONFIDENTIAL
10
From case to product
from market need t...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
11
CONFIDENTIAL
From case to product
Product definition...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
12
CONFIDENTIAL
From case to product
Main functions
• A...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
CONFIDENTIAL
13
Design to Cost
Insights
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
14
CONFIDENTIAL
Project approach
Design to cost
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
15
CONFIDENTIAL
Project approach
Design to cost
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
16
CONFIDENTIAL
Project approach
• Design to cost start...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
17
CONFIDENTIAL
Design to cost
Project approach
FFE
Fea...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
18
CONFIDENTIAL
Project approach
Cost can be influenced...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
19
CONFIDENTIAL
Fujirebio Tendigo ™ case
Very inelastic...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
CONFIDENTIAL
20
Design to Cost
Practical tools
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
21
CONFIDENTIAL
Different project phases = different te...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
22
CONFIDENTIAL
Project start (fuzzy front end & feasib...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
23
CONFIDENTIAL
Project start (fuzzy front end & feasib...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
24
CONFIDENTIAL
Project start (fuzzy front end & feasib...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
25
CONFIDENTIAL
Project start (fuzzy front end & feasib...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
26
CONFIDENTIAL
Design freedom knowledge
Development cy...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
27
CONFIDENTIAL
1st design & prototype tests
• System a...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
28
CONFIDENTIAL
1st design & prototype tests
BOM analys...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
29
CONFIDENTIAL
Design freedom knowledge
Development cy...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
30
CONFIDENTIAL
2nd design & prototype tests
• First pr...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
31
CONFIDENTIAL
2nd design & prototype tests
Design to ...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
CONFIDENTIAL
32
Conclusions
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
33
CONFIDENTIAL
Design to cost
• Very useful design met...
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
34
CONFIDENTIAL
Conclusions
Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost
Kruibeke
Belgium
Verhaert New Products & Services
Hogen...
Upcoming SlideShare
Loading in …5
×

2015 innovation day_fujirebio tendigo design to cost_verhaert_frederik mortier_v2

1,964 views

Published on

Frederik Mortier talks about design to cost in the Fujirebio tendigo project. Verhaert innovation day 2015.

Published in: Engineering
  • Be the first to comment

  • Be the first to like this

2015 innovation day_fujirebio tendigo design to cost_verhaert_frederik mortier_v2

  1. 1. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost Template Innovation Day presentationCONFIDENTIAL FUJIREBIO TENDIGO™, AN ASSAY PROCESSING INSTRUMENT: DESIGN TO COST Frederik Mortier Consultant applied Physics & Systems frederik.mortier@verhaert.com MEDICAL: CONVERGENCE IN HEALTH CARE
  2. 2. 2 Frederik Mortier Consultant Applied Physics & Systems 2012- now Researcher @ Ghent University 2011-2012 MSc. in Engineering – Electro-Mechanical 2009-2011 MSc. in Industrial Sciences – Electro-Mechanical 2005-2009 frederik.mortier@verhaert.com
  3. 3. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 3 CONFIDENTIAL 1 2 3 4 5 CONTENT Introduction Fujirebio Business case TENDIGO™ From case to product Design to Cost methodologies Conclusions
  4. 4. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost CONFIDENTIAL 4 Fujirebio Company introduction
  5. 5. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 5 CONFIDENTIAL Introduction Fujirebio Europe N.V. • Healthcare company • Formerly Innogenetics N.V. • Located in Zwijnaarde Core business Fujirebio Europe • R&D and production of in vitro diagnostics (IVD) testing solutions Collaboration with Verhaert • Mid 2012  now • Device development • Manufacturing of devices
  6. 6. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 6 CONFIDENTIAL Introduction IVD testing solution: assay • Strip based diagnostics • 5-6 different liquids • Infectious diseases (HIV, Syphilis, ..) Assay processing • Precise liquid dosing • Correct timing • Highly accurate temperature profile Verhaert & Fujirebio • Development & production of assay processor (automation) • Product browser Fujirebio
  7. 7. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost CONFIDENTIAL 7 Business case TENDIGO™ assay processor
  8. 8. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 8 CONFIDENTIAL Business case Business model Fujirebio  Development & sales of assays Development of an assay processor as a facilitator for • Regional expansion • New customers • Sales through distributor network • Leverage current product portfolio • Increase ease of use • less time consuming  potential of more tests/customer • Market focused offering • Existing small, manual customer could be offered automation • strong requirement for automation (cost & quality)  TENDIGO™is a delivery system! It’s not about the device, it’s about the consumables
  9. 9. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 9 CONFIDENTIAL Business case How to define the perfect product? Landscaping of current automation solutions • Expensive, high end device for high throughput uses • Medium throughput device is phased out Investigate market segmentation • Automated vs. Manual users  519 vs. 900 • Kits/user  >50% buys less than 10kits/year • User per region Benefits manual  automation • 2-3h to 20mins hands-on time • Increased quality (27% of complaints are user mistakes) • One-stop shopping Convergence in health care  Solution thinking!
  10. 10. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost CONFIDENTIAL 10 From case to product from market need to product definition
  11. 11. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 11 CONFIDENTIAL From case to product Product definition Focus on convergence manual  automation • Low cost device: € 3-5k ex-works(high end device €15-20k) • Low throughput: 10 strips/run (1/2 kit) • 100runs/year typical use • 100 devices/year Low cost does not mean low quality  medical device! Need for Design to Cost methodologies!
  12. 12. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 12 CONFIDENTIAL From case to product Main functions • Accurate heating of liquids & strips • Accurate pick & place of liquid doses Building blocks • Modular building blocks defined
  13. 13. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost CONFIDENTIAL 13 Design to Cost Insights
  14. 14. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 14 CONFIDENTIAL Project approach Design to cost
  15. 15. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 15 CONFIDENTIAL Project approach Design to cost
  16. 16. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 16 CONFIDENTIAL Project approach • Design to cost starts right away! • 2/3 of life cycle cost is committed by design Design to cost Most significant cost influence!
  17. 17. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 17 CONFIDENTIAL Design to cost Project approach FFE Feasibility study 1st design 1st prototype testing Redesign 2nd prototype testing Manufacturing mid 2012 mid 2015
  18. 18. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 18 CONFIDENTIAL Project approach Cost can be influenced by more than design alone – 3 fold management  Design to Cost = Risk management Design to cost Performance Planning Risk management Price
  19. 19. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 19 CONFIDENTIAL Fujirebio Tendigo ™ case Very inelastic circumstances 1. Planning Planning was ‘fixed’ 2. Price Instrument price was ‘fixed’, development budget was ‘fixed’ 3. Performance Medical device limitations  Significant need for Design to Cost! Design to cost
  20. 20. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost CONFIDENTIAL 20 Design to Cost Practical tools
  21. 21. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 21 CONFIDENTIAL Different project phases = different techniques Design to cost Design freedom knowledge Development cycle FFE Feasibility study 1st design 1st prototype testing Redesign 2nd prototype testing Manufacturing mid 2012 mid 2015
  22. 22. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 22 CONFIDENTIAL Project start (fuzzy front end & feasibility) • Lack of information & • Largest influence on project cost  Important choices to be made! Approach • Gain information through early stage feasibility testing! • focus on architectural level • Split up in modules / functions • KISS: ‘keep it simple & stupid’ methodology • Trade offs • Total product cost ~ part quantity x part cost • Reduce part quantity • Reduce part cost • Value engineering Design to cost
  23. 23. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 23 CONFIDENTIAL Project start (fuzzy front end & feasibility) Examples • Overall system architecture • Trade off • Visualization • Criteria definition • Cost • Performance • Timing Design to cost
  24. 24. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 24 CONFIDENTIAL Project start (fuzzy front end & feasibility) Examples • Heating:  Temperature function reduced to dry aluminium block heater • Dosing:  Multiple peristaltic pumps reduced to single syringe • Mechanical:  Simple flat plate design (low sales volume) • Robotics:  Number of axes reduced to minimum, simple feed forward stepper drives Design to cost
  25. 25. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 25 CONFIDENTIAL Project start (fuzzy front end & feasibility) Value engineering Value = Function / Cost  evaluation of value! Examples  Determine perceived value through mockup evaluation • Device height • Display position • ..  Question instrument specifications • Rocking of RT tray • Heat up time RT tray • .. Design to cost FOTO MOCKUP
  26. 26. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 26 CONFIDENTIAL Design freedom knowledge Development cycle Different project phases = different techniques Design to cost FFE Feasibility study 1st design 1st prototype testing Redesign 2nd prototype testing Manufacturing mid 2012 mid 2015
  27. 27. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 27 CONFIDENTIAL 1st design & prototype tests • System architecture already chosen • Detailed cost information available • Feasibility tests conducted  gained knowledge  Design changes wrt feasibility study are often cost or performance driven Approach • BOM structuring & detailing • Split up in function / modules / building blocks • Identify per part type (buy, custom, electronics…) • Estimate high & low price  cost range! • .. • BOM analysis • Pareto analysis  80/20 • Min – Max instrument cost estimation • Supplier grouping • Building block cost comparison • .. Design to cost
  28. 28. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 28 CONFIDENTIAL 1st design & prototype tests BOM analysis Design to cost Module split up Part type Cost range (high vs low) Cost ranking Supplier sourcing BOM analysis proved to be a very useful tool! Effort focussed for maximum efficiency Clear oversight of cost distribution
  29. 29. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 29 CONFIDENTIAL Design freedom knowledge Development cycle Feasibility study 1st prototype testing 2nd prototype testing mid 2012 mid 2015 Different project phases = different techniques Design to cost FFE 1st design Redesign Manufacturing
  30. 30. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 30 CONFIDENTIAL 2nd design & prototype tests • First prototype tests conducted • First user experience  Design changes mainly test result or user input driven Approach • Action list  trade off (value engineering) • Cost vs. added value of change! • Distinctions between nice to haves & musts Design to cost
  31. 31. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 31 CONFIDENTIAL 2nd design & prototype tests Design to cost
  32. 32. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost CONFIDENTIAL 32 Conclusions
  33. 33. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 33 CONFIDENTIAL Design to cost • Very useful design methodology • Based upon plain & simple common sense • Different approaches for different project phases Early stage vs. finalization • Design methodology & risk management technique • Many useful tools available Case study Fujirebio Tendigo™ • Methodology is way of thinking of entire team • Design to Cost was essential in achieving our goal! • Production started July 2015 • First sales past month Conclusions Design freedom knowledge Development cycle
  34. 34. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost 34 CONFIDENTIAL Conclusions
  35. 35. Fujirebio Tendigo™: An Assay Processing Instrument: Design To Cost Kruibeke Belgium Verhaert New Products & Services Hogenakkerhoekstraat 21 B-9150 Kruibeke T +32 3 250 19 00 E info@verhaert.com www.verhaert.com Nivelles Belgium Noordwijk Netherlands Lambda-X Avenue Robert Schuman 102 B-1400 Nivelles T +32 67 47 57 10 E info@lambda-x.com www.lambda-x.com Verhaert Netherlands Kapteynstraat 1 2201 BB Noordwijk T +31 71 760 05 50 E info@verhaert.com connect.verhaert.com INDUSTRYFMCGCONNECT MEDICAL TECHXFER MEDICALAEROSPACE TECHXFER FMCGCONNECT TECHXFER Aveiro Portugal Load Interactive Av. Dr. Lourenço Peixinho 15 3800-159 Aveiro T +351 234 604 088 E info@load-interactive.com www.load-interactive.com CONNECT Masters in Innovation is the innovation platform of Verhaert to inspire and coach professionals on product and business development and management. Innovation Day is an initiative of Verhaert Masters in Innovation.

×