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From Strength in Diversity to Smart Nanoscale Technologies - David Smith

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David is talking about amazing technologies and nanochemistry

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From Strength in Diversity to Smart Nanoscale Technologies - David Smith

  1. 1. Prof. David K. Smith University of York UNIT 2017, Berlin, Germany May 2017@professor_dave From Strength in Diversity… To Smart Nanoscale Technologies
  2. 2. Prof. David K. Smith University of York @professor_dave
  3. 3. Prof. David K. Smith University of York My Educational Environment @professor_dave
  4. 4. Prof. David K. Smith University of York My Educational Environment @professor_dave
  5. 5. Prof. David K. Smith University of York Science in Schools @professor_dave ‘David says it would have helped him to have a teacher who was a point of contact for students with LGBT issues. While he had many teachers who made a huge difference in his scientific development, this was not related to finding his LGBT identity’ Joseph Unsay
  6. 6. http://www.youtube.com/professordaveatyork Prof. David K. Smith University of York YouTube @professor_dave
  7. 7. Prof. David K. Smith University of York Chemistry World Article @professor_dave
  8. 8. ‘You are mistaking us for people who give a ****. Your sexuality is NOT important vis-a-vis your job’. ‘So your fellow scientists don't give a shite about your sexuality, just your research credentials and publication records? Isn't that equality?’ Meritocracy or ‘Don’t Ask Don’t Tell’? Prof. David K. Smith University of York Is Science Diverse and Equal? @professor_dave
  9. 9. ‘I had violated an unspoken convention of STEM: the invisibility of its LGBT members’ Manil Suri Prof. David K. Smith University of York Straight Science? @professor_dave https://www.nytimes.com/2015/09/05/opinion/manil-suri-why-is-science-so-straight.html Why is Science so Straight?
  10. 10. Publication Prof. David K. Smith University of York Young LGBT Scientists @professor_dave ‘Except for rumour we have zero LGBT staff or students here. It is quite isolating’ Anonymous Chemistry Student in Major UK Metropolitan University
  11. 11. Prof. David K. Smith University of York Young Scientists? @professor_dave
  12. 12. ‘I am thinking about coming out to my fellow lab mates and maybe also to my supervisor (when it comes up in a chat naturally), but I am still not quite sure about it.’ Prof. David K. Smith University of York Young Scientists @professor_dave ‘A lot of people worry that there will be unconscious bias against them in the job hunting process. This should be something we are happy to discuss as scientists. It should just be a part of life.’ Female Researcher (Anon):
  13. 13. A junior researcher’s supervisor can have a lot of influence on their prospects, many researchers think it is necessary to avoid personal details. ‘If you can’t even have a conversation with a colleague about who you spent the weekend with it’s not a nice working environment’ Prof. David K. Smith University of York Being 100% Yourself @professor_dave Matthew Mears, University of Sheffield
  14. 14. ‘Throughout my academic life in Chemistry, I've found it normally has a very conservative, macho culture. Any sexuality related issues are met with embarrassment or sometimes hostility, more so than other academic areas. It doesn't help on an emotional level, leading to feelings of isolation perhaps leading to giving up on a science career.’ Academic (Anon) Prof. David K. Smith University of York STEM Cultural Problems @professor_dave
  15. 15. Prof. David K. Smith University of York LGBT STEM Survey http://www.queerstem.org@professor_dave How ‘Out’ Are You? Is Your Workplace? J. Homosexuality, DOI 10.1080/00918369.2015.1078632
  16. 16. Research Fortnight Magazine http://tinyurl.com/researchfortnight Prof. David K. Smith University of York Don’t Ask, Don’t Tell @professor_dave
  17. 17. Prof. David K. Smith University of York My Research Motivation @professor_dave
  18. 18. S.J. Shieh, J.P. Vacanti, Surgery 2005, 137, 1-7 Prof. David K. Smith University of York Tissue Engineering New Organs A smart ‘matrix’ could encourage cell differentiation @professor_dave Matrix = Gel A.R. Hirst, D.K. Smith, et al, Angew. Chem. Int. Ed. 2008, 47, 8002
  19. 19. Polymer Gels Prof. David K. Smith University of York @professor_dave
  20. 20. We Can Do This! Prof. David K. Smith University of York @professor_dave
  21. 21. Self-Assembly Prof. David K. Smith University of York @professor_dave
  22. 22. Prof. David K. Smith University of York Nanoscience @professor_dave
  23. 23. Inspiration from History Prof. David K. Smith University of York M. J. Meunier, Ann. Chim. Phys. 1891, 22, 412 @professor_dave B.O. Okesola, V.M.P. Vieira, D.J. Cornwell, N.K. Whitelaw, D.K. Smith Soft Matter 2015, 11, 4768-4787 E. L. Roehl, US Patent 4,346,079, 1982 T. Ando and Y. Yamazaki, US Patent, 3846363, 1974
  24. 24. DBS – Butterfly Surfactant Prof. David K. Smith University of York B.O. Okesola, V.M.P. Vieira, D.J. Cornwell, N.K. Whitelaw, D.K. Smith Soft Matter 2015, 11, 4768-4787 @professor_dave
  25. 25. Embedded Hybrid Nanostructures Biology is Aqueous @professor_dave Prof. David K. Smith University of York
  26. 26. Innovative DBS Hydrogels Prof. David K. Smith University of York B.O. Okesola, D.K. Smith, Chem. Commun. 2013, 49, 11164 D.J. Cornwell, B.O. Okesola, D.K. Smith, Soft Matter 2013, 9, 8730 @professor_dave Modified Wings Two New Hydrogelators
  27. 27. Embedded Hybrid NanostructuresTissue Growth Prof. David K. Smith University of York @professor_dave 3T3 Cells – mouse embryonic fibroblasts Cell growth on DBS-CONHNH2 transwells With Nano-FM Groningen, NL V. M. P. Vieira, M de Jong, D.K. Smith, unpublished results
  28. 28. Prof. David K. Smith University of York Problems @professor_dave Complexity Many cell types Structural organisation Cellular communication High-level function Use a Complex Self-Organised Gel to Program Cellular Function From Multi-Component Chemistry to Multi-Component Biology
  29. 29. Prof. David K. Smith University of York Harnessing Chemical Diversity To Achieve Biological Function@professor_dave Diverse Inputs
  30. 30. Envirogel B.O. Okesola, D.K. Smith, Chem. Commun. 2013, 49, 11164 Embedded Hybrid Nanostructures Innovative Technology 1 Interactive Gels Prof. David K. Smith University of York @professor_dave
  31. 31. Embedded Hybrid Nanostructures Controlled Release from Interactive Gels Prof. David K. Smith University of York @professor_dave E.J. Howe, B.O. Okesola, D.K. Smith, Chem. Commun. 2015, 51, 7451 Painkillers Drugs bound at low pH (stomach), released at pH 8 (intestine) pH=4 pH=8 pH=7100 80 60 40 20 20 40 % Release Hours
  32. 32. Embedded Hybrid Nanostructures Innovative Technology 2 Hybrid Hydrogels Prof. David K. Smith University of York @professor_dave D.J. Cornwell, D.K. Smith Mater. Horiz. 2015, 2, 278 Self-Assembled Gel Polymer GelHybrid Gel Responsive RobustAND
  33. 33. Photoinitiator UV, 10 min pH Embedded Hybrid Nanostructures Hybrid Hydrogels In Action Prof. David K. Smith University of York @professor_dave D.J. Cornwell, B.O. Okesola, D.K. Smith, Angew. Chem. Int. Ed. 2014, 53, 12461 Can Polymerise Can Assemble Robust Robust And Responsive
  34. 34. Multi-domain gels – Masking during UV stimulation enables regions of hybrid gel and non-hybrid gel to form with spatial control in a bulk sample: Solution of LMWG and PG (+ PI and GdL)Apply mask......cure under UV lightPG network forms...... followed by LMWG network over time Embedded Hybrid Nanostructures Innovative Technology 3 Spatially Resolved Gels Prof. David K. Smith University of York @professor_dave D.J. Cornwell, B.O. Okesola, D.K. Smith, Angew. Chem. Int. Ed. 2014, 53, 12461
  35. 35. Regions with different material strength: Multi- domain gel Weak LMWG domain Robust PG+LMWG domain Embedded Hybrid NanostructuresMulti-Domain Gels Prof. David K. Smith University of York @professor_dave D.J. Cornwell, B.O. Okesola, D.K. Smith, Angew. Chem. Int. Ed. 2014, 53, 12461 Spatially resolved rheological performance Stem cells differentiate on different domains
  36. 36. Embedded Hybrid Nanostructures Combining Technologies Prof. David K. Smith University of York @professor_dave P.R.A. Chivers, D.K. Smith, Manuscript submitted UV 30 min pH 3 pH 7 Directional Release
  37. 37.  Clean water obtained  Maximum gold loading =1915 mg/g  Thermally and pH stable nanoparticle-gel Au3+ Embedded Hybrid Nanostructures Innovative Technology 4 Conductive Gels Prof. David K. Smith University of York @professor_dave B.O. Okesola, S.K. Survaram, A. Parkin, D.K. Smith Angew. Chem. Int. Ed. 2016, 55, 183-187
  38. 38. Embedded Hybrid Nanostructures Hybrid Conducting Gels Prof. David K. Smith University of York @professor_dave 0 50 100 150 200 250 300 Basic-Gel Nano-Gel Gel + SWNT Conductivity/mScm-1 Solvated Gel Gel - 30% of Water Removed B.O. Okesola, S.K. Survaram, A. Parkin, D.K. Smith Angew. Chem. Int. Ed. 2016, 55, 183-187 Interactive hydrogel Polymer hydrogel Organises Gold/Silver Robust Material
  39. 39. Complexity in Tissue Growth Simple Self-Assembly of Diverse Components Commercial Hybrid Interactive ConductingPatterned From Multi-Component Chemistry to Multi-Component Biology From New Technologies Into the Future Prof. David K. Smith University of York @professor_dave
  40. 40. Publication Prof. David K. Smith University of York Science @professor_dave
  41. 41. Publication Prof. David K. Smith University of York YouTube Outreach @professor_dave
  42. 42. Publication Prof. David K. Smith University of York My Working Environment @professor_dave
  43. 43. Publication Prof. David K. Smith University of York Chemistry at York @professor_dave
  44. 44. Publication Prof. David K. Smith University of York York Changing the Ethos@professor_dave Tim Bradbury ‘There is gossip in the department about Dave Smith It is homophobic in nature, and is making some of us very uncomfortable’ 2005
  45. 45. Publication Prof. David K. Smith University of York Year 1 Introduction to Organic Chemistry@professor_dave
  46. 46. Publication Prof. David K. Smith University of York Individual Steps @professor_dave
  47. 47. @professor_dave Publication Prof. David K. Smith University of York Twitter @professor_dave
  48. 48. Publication Prof. David K. Smith University of York Sharing @professor_dave #adoption
  49. 49. ‘It's important for LGBT students like me to see that there are people like us who make it higher up and do great things with their lives in our field of study - we see that we too can have a future like that.’ Publication Prof. David K. Smith University of York LGBT Chemistry Student Survey@professor_dave ‘It made me feel a lot better, having come from a school where LGBTQ welfare was swept under the carpet and there were next to no “out” students or teachers. It helped my coming out process.’
  50. 50. Publication Prof. David K. Smith University of York Wider Student Media @professor_dave
  51. 51. Publication Prof. David K. Smith University of York Embedding within Departmental Ethos@professor_dave
  52. 52. Publication Prof. David K. Smith University of York LGBT Games @professor_dave Chris Unsworth Chemistry, Yr 2 PhD Laurence Bastidas Chemistry, Yr 1 “The University of York is very progressive, particularly with respect to diversity and inclusion,” he told Attitude. http://attitude.co.uk/york-university-sending-swim-team-to-stockholm-eurogames/
  53. 53. Publication Prof. David K. Smith University of York Talk @professor_dave
  54. 54. Publication Prof. David K. Smith University of York Turning Point? @professor_dave Interview on LGBT representation in science Nature 2016, 531, 265
  55. 55. ‘Diverse scientists will have diverse ideas and approaches – essential for cutting-edge research Happy and fulfilled scientists will perform better. If we only care about the science, and not the people who do it, we won’t achieve the best results’ Publication Prof. David K. Smith University of York Scientists are Individuals @professor_dave Chemistry World, April 2014

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