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Ch parenteral dosage form & its classification

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Ch parenteral dosage form & its classification

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parenteral dosage form
its classification
advantages & disadvantages
parenteral routes
general requirements
official types of injections
preformulation studies
parenterals vehicles
formulation of parenterals
water for injection
small volume parenterals
large volume parenterals
labeling
packaging
test for packaging
storage of parenterals

parenteral dosage form
its classification
advantages & disadvantages
parenteral routes
general requirements
official types of injections
preformulation studies
parenterals vehicles
formulation of parenterals
water for injection
small volume parenterals
large volume parenterals
labeling
packaging
test for packaging
storage of parenterals

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Ch parenteral dosage form & its classification

  1. 1. Ch- Parenteral dosage form (Introduction and its classification) Subject: Formulative Pharmacy BP-502 T By: Ms. Uditi Handa (Asst. Prof.) M.Pharma (Ph.D) GGSCOP, Yamunanagar
  2. 2. Volume: 0.01-0.05 ml Needle size: 25-26 gauge Formulation: isotonic Used: Diagnostic agents Volume: 0.5-2 ml Needle size: 23 gauge Formulation: isotonic Used: Insulin, vaccines Volume: 1-1000 ml Needle size: 20-22 gauge (Vein puncture) & 18-19 gauge (Venolysis) Formulation: Solutions, emulsion Used: Nearly all drugs
  3. 3. Volume: 2-20 ml Needle size: 20-22 gauge Formulation: Solutions & emulsion Used: Radiopaque media, antineoplastics, Antibiotics Volume: 1-4 ml Needle size: 24-28 gauge Formulation: isotonic Used: Local anesthetics, analgesic, neuroleptic agents
  4. 4. Volume: 2-20 ml Needle size: 18-22 gauge Formulation: isotonic Used: Morphine, Local anesthetics, Steroids, Antibiotics Volume: 0.5-2 ml Needle size: 22 gauge Formulation: Solutions & emulsion, Suspension Used: Nearly all drugs Volume: 0.2-1 ml Needle size: 22 gauge Used: Cardio tonic drugs, Calcium
  5. 5. Volume: 6-30 ml Needle size: 16-18 gauge Formulation: isotonic Used: Local anesthetics, narcotics, Steroids Volume: 2-30 ml Needle size: 16-22 gauge Formulation: isotonic Used: Local anesthetics, narcotics, chemotherapeutic agents Intrapleural Route • Directly into the lungs
  6. 6. Official types of injections
  7. 7. • Natural Water: is not used for drinking or any pharmaceutical formulation. It is highly contaminated. • Drinking water: may be used in the early stage of chemical synthesis and in the early stages of the cleaning of pharmaceutical manufacturing equipments. • Purified water: (USP monograph), is used in the preparation of some bulk pharmaceutical chemicals, do not use purified water in preparations intended for parenteral administration. • Must be protected from microbial proliferation. • Sterile purified water: Is purified water that is packaged and rendered sterile, contains no antimicrobial agent. • It is not for parenteral administration. Considerations in parenteral preparation Vehicles not used in Parenterals
  8. 8. 1 2
  9. 9. References Parenteral - an overview | ScienceDirect Topics www.sciencedirect.com Introduction to Parenteral Preparations samples.jbpub.com Thank you

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