1. Reuma-diagnostiek in
beweging
Martin Salden

2. ED-Group:
Euro-
Diagnostica
AB
Euro-
Diagnostica Wieslab AB
ABDB
Wieslab BV Wieslab XX

3. Draupnir
Draupnir
Services B.V.
ED- Nordic PPL
Group Group Group

4. Draupnir

5. PolyPeptide Group
• One of the world's leading groups specialized in
the industrial scale manufacture of custom and
generic peptides for therapeutic (and cosmetic)
applications.
• Manufacturing facilities in Denmark, Sweden,
France, Czech Republic, USA and India.

6. Nordic Group
• The Nordic Group is a fully-integrated, pan-European
Pharmaceutical Group.
• Nordic Group focuses on two specialized segments
of the Pharmaceutical market:
- Marketing & Sales of specialty (generic)
pharmaceuticals;
- Specialized Pharmaceutical Services focusing on
Product Development, Manufacturing, supply
Logistics and Regulatory activities.

7. Euro-Diagnostica Group
• Euro-Diagnostica focuses on the diagnosis and
monitoring of specific diseases.
• Euro-Diagnostica develops, manufactures and
markets complete diagnostic kits and reagents
for use in special medical areas like autoimmune
diseases and Rheumatology.
• The Group operates from establishments in
Nijmegen (The Netherlands) and Malmö
(Sweden)

8. Formation of the company
• 1992: Euro-Diagnostica established by a merger of
– Ferring Diagnostica, SE
– BioCarb Diagnostics, SE
– Euro-Diagnostics, NL
– Medscand Diagnostics-MILAB, SE

9. Strategic Mergers and Acquisitions
• 2004: Acquisition of Wieslab AB
– Well established trade name
– Added further competence in protein chemistry
– Key competence in developing ANCA tests
– Scandinavia`s leading private autoimmune laboratory

10. EuroDiagnostica/Wieslab
• Employees
– Malmö, E-DEON Sweden, 70 employees
– Nijmegen, Mercator 3 building,The Netherlands, 6 employees

11. World Wide Distribution Network
• Key Markets
– North America – Own distribution of
– Europe products in the Nordic
countries, Benelux, UK and
– Japan
Germany

12. Cutting Edge Diagnostics
• Euro-Diagnostica is the leader in the development of unique
– ANCA tests – Vasculitis diagnosis
– Anti-CCP2 based tests – Rheumatoid Arthritis diagnosis

13. anti-CCP2 ELISA
• The ultimate serological marker for diagnosis of Rheumatoid
Arthritis
– Specific – Allows early detection of RA
– Sensitive – Prognostic marker

14. CCPoint® anti-CCP point-of-care test
• The first POC test for anti-CCP
– Enables near-patient diagnosis of RA
– Enables rapid diagnosis – rapid treatment
– Specific and sensitive as ELISA
• Wieslab® SSA p200 ELISA
• Wieslab® Complement ELISA

15. CCP assay based on discovery of Prof van Venrooij
• STW agreement
– IP protection. Prepare to defend ?
• Product development
– Core technology.
– BioBank to validate product.
• Marketing & Sales
– ED brand, protect product name CCP!
– OEM, no competitive products!
– Inventor best promoter of product
• Personal click

16. Add 1 drop of blood Add 5 drops of chase buffer
Open the flip-up after 30 sec
Read the results after 10 min

18. Areas of clinical competence
• Systemic vasculitidies. Rapidly progressing
glomerulonehritis.
• Reference laboratory for ANCA testing
• Complete range of autoimmune analyses

19. Service for clients
• Acute testing for ANCA and anti-GBM daily 7/24
• Support and interpretation of test results
• Analysis packages according to client’s wishes

20. 24 hour service for ANCA and anti-GBM
• Rapidly progressing glomerulonephritis
• Acute reno-pulmonary syndromes
• Qualitative testing of PR3-ANCA, MPO-ANCA and anti-GBM.
High sensitivity.
• Results within one hour from the sample reaching the laboratory
• Positive results are confirmed by quantitative ELISA the
following day