1. FEDERAL UNIVERSITY DUTSE
STUDENT INDUSTRIAL WORK EXPERIENCE
BIORESOURCES DEVELOPMENT CENTRE KANO
BAYERO UNIVERSITY KANO (NEW CAMPUS)
RABIU KUDIROH OMOSALEWA
MR ADEPOJU MALIK
December – May, 2022
2. HISTORY OF BIODEC KANO
• Bioresources Development Center (BIODEC) Kano formerly
known as Aquaculture Training Centre kano, was established by
the National Biotechnology Development Agency in the year
2012 to support the agency’s delivery of indigenous bioresource
• The center was upgraded to a BIODEC center in the year 2014 in
order to play a critical role in the sustainable development and use
of indigenous bioresources through the application of emerging
science and technology, at the same time empowering people in
kano, and its neighboring states and technical skills in order to
boost food production, health, job creation and wealth.
4. ACUTE TOXICITY
Acute toxicity is calculated using LD50.
LD50 Median lethal dose, is a dose that can kill 50% of a tested population, the unit of
LD50 is mg/kg, there are two methods of LD50
DETERMINATION OF THE ACUTE TOXICITY ON AN ANTI-ULCER HERBAL MEDICINE
USING LORKE`S METHOD.
They are two phase, phase1 and phase2
PHASE1: 9 mice were used in this phase and were grouped into three groups consisting
of 3 mice each, the herbal medicine was administrated to each group
Group1_10mg/kg, Group2_100mg/kg, Group3_1000mg/kg
The phase one mice were observed for 24 hours to check for mortality.
PHASE2: 4 mice were used in this phase, and the observation from phase 1 determine
the amount of herbs to be administered to the mice in phase2.
5. RESULTS AND CONCLUSION
Phase1:After 24 hours of observation
Group1_ 0/3, no mortality
Group2_0/3, no mortality
Group3_0/3, no mortality.
Phase2: from the observation in phase one, according to LD50 table the four mice in
phase were administered 1200mg/kg, 1600mgmg/kg, 2900mg/kg, 5000mg/kg.
1200mg/kg_ 0/1, no mortality
1600mg/kg_ 1/1, mortality
2900mg/kg_ 1/1, mortality
500mg/kg_ 1/1, mortality