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• Proudly introducing
• “The Harrington Project for Discovery &
Development”
Bridging the Valley of Death
Baiju R. Shah, C...
1
More Money…Fewer Medicines
1
Source: Diagnosing the decline in pharmaceutical R&D efficiency (2012); Burrill & Company a...
2Source Image: “Translational Research: Crossing the Valley of Death,” Nature, June 11, 2008
The Valley of Death
Developing New Medicines
LateClinical
EarlyClinical
Pre-Clinical
Product
Discovery
To Heal. To Teach. To Discover.
Developing New Medicines
LateClinical
EarlyClinical
Pre-Clinical
Product
Discovery
Opportunity for Innovation
“There’s never been a time where we’ve had
a greater outpouring of discoveries about the
nature...
To Heal. To Teach. To Discover.
Bridging the Valley of Death
LateClinical
EarlyClinical
Pre-Clinical
Product
Discovery
Val...
To Heal. To Teach. To Discover.
7
Accelerating Breakthrough Discoveries into Medicines
Nonprofit For-Profit
Breakthrough
M...
To Heal. To Teach. To Discover.
8
Current Technologies
THP
To Heal. To Teach. To Discover.
Bridging the Valley of Death
Source Image: “Translational Research: Crossing the Valley of...
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Baiju Shah

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Baiju Shah

  1. 1. • Proudly introducing • “The Harrington Project for Discovery & Development” Bridging the Valley of Death Baiju R. Shah, CEO, BioMotiv The Harrington Project for Discovery & Development TEDxCLE April 4, 2014
  2. 2. 1 More Money…Fewer Medicines 1 Source: Diagnosing the decline in pharmaceutical R&D efficiency (2012); Burrill & Company analysis for PhRMA (2008) $ Bns, R&D New Drugs
  3. 3. 2Source Image: “Translational Research: Crossing the Valley of Death,” Nature, June 11, 2008 The Valley of Death
  4. 4. Developing New Medicines LateClinical EarlyClinical Pre-Clinical Product Discovery
  5. 5. To Heal. To Teach. To Discover. Developing New Medicines LateClinical EarlyClinical Pre-Clinical Product Discovery
  6. 6. Opportunity for Innovation “There’s never been a time where we’ve had a greater outpouring of discoveries about the nature of disease. And yet paradoxically, the ability to turn that information into clinical applications seems to have slowed down. If there was ever a time when we need to figure out how to take this wonderful scientific opportunity and apply the most bold, audacious principles of innovation to make those products happen, it is now.” Dr. Francis Collins NIH Director
  7. 7. To Heal. To Teach. To Discover. Bridging the Valley of Death LateClinical EarlyClinical Pre-Clinical Product Discovery Valley of Death
  8. 8. To Heal. To Teach. To Discover. 7 Accelerating Breakthrough Discoveries into Medicines Nonprofit For-Profit Breakthrough Medicines Harrington Discovery Institute Innovation Center Research Institutions and Disease Foundations BioMotiv
  9. 9. To Heal. To Teach. To Discover. 8 Current Technologies THP
  10. 10. To Heal. To Teach. To Discover. Bridging the Valley of Death Source Image: “Translational Research: Crossing the Valley of Death,” Nature, June 11, 2008

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