1. Brad Cunningham
SystemOne, LLC
bcunningham@systemone.id
Connectivity Needs for Improved Patient Care
Translating Laboratory Informatics into Patient Care: mHealth & Implementation
Science Research
ASLM Conference, Cape Town
3 December, 2016
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2. Adoption in TB Through 2015
MARKET IS GROWING @ 14% PER MONTH
MORE THAN 2,000 GENEXPERTS ARE ALREADY PROGRAMMED FOR
CONNECTIVITY, ACROSS 32 DEVELOPING NATIONS

3. © SystemOne, 2016 All rights reserved.
• Translating real-time data into real-time
actionTreatment
• Diagnostics moving further away from
centralized, well-controlled environmentsQuality
• Optimize utilization of instruments,
consumption of consumables, improve ROICost
Faster, better quality health
data leads to better patient
outcomes

4. Misnomer
>> Connectivity
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• Expect POC
instruments to traverse
multiple network types /
speeds (3+) each day
• Wide variety in signal
strength / quality

5. Patient
Care
Patient
Management
Logistics
Diagnosis
Linkage to
Care
© SystemOne LLC, 2016 All rights reserved.
Emerging mHealth trends in
the HIV/TB sector

6. Patient
Care
Patient
Management
Logistics
Diagnosis
Linkage to
Care
Patient Management:
• Geo-locating
• Health-care contact info
• Home-care help
• Incentive-based care
• Appointment booking
• Patient registration
• Patient identification
• (direct) Contact information
• Visit management & workflow
• Screening
• Sample Collection
• Education, awareness & outreach
• Result delivery
• Re-engagement
• Linkage to care
© SystemOne LLC, 2016 All rights reserved.

7. Patient
Care
Patient
Management
Logistics
Diagnosis
Linkage to
Care
Logistics:
• Test order requests
• ‘Smart’ courier
• Sample transport tracking
• Transport recording
• Demand-based logistic routes
• Reduce time-to-diagnosis
• Improved consumable
management
• Reduce stock shortages
• Reduce gross over-purchasing
of consumables
© SystemOne LLC, 2016 All rights reserved.

8. Patient
Care
Patient
Management
Logistics
Diagnosis
Linkage to
Care
Diagnosis:
• Recording & interpretation (RDT’s)
• (ongoing) Quality Assurance
• Measurement of ‘lab’ environment
• Linking diagnosis to individuals
• Reporting
• Follow-up & reflexing
• Real-time result delivery
• Notifications (SMS, e-mail, in-app)
• Patient
• Doctor
• Nurses
• Care centres (MDR, as
example)
© SystemOne LLC, 2016 All rights reserved.

9. Patient
Care
Patient
Management
Logistics
Diagnosis
Linkage to
Care
Linkage to Care:
• Clinical translation of diagnostic &
connectivity efforts
• Making sure the right data:
• Gets to the right person
• At the right time
• With the right information
• In an appropriate manner
• Reduced time to result reporting
• Get patient onto treatment
faster
• Improve initiation on care
• Social engagement & personal care
approach to increase retention in
care & loss to follow up
© SystemOne LLC, 2016 All rights reserved.

10. Patient
Care
Patient
Management
Logistics
Diagnosis
Linkage to
Care
Where do things go
wrong?
• Do everything
• Healthcare is too broad, too
diverse.
• Start small
• Micro-populations.
• Address specific need of the
population
• Show value
• Evolve
• Scale out
© SystemOne LLC, 2016 All rights reserved.

11. Where are we now?
“Connectivity” is no longer a single result or even
a single system – connectivity is an ecosystem of platforms
exchanging data.
• Emerging interoperability & standards
• Developing best-practises in the field
• Limited-scope patient engagement in cycle
• Avoid persistent fragmentation
• Web-based / cloud adoption increasing
• Smarter devices (phones & diagnostics)
• Clinical translation lacking
© SystemOne LLC, 2016 All rights reserved.

12. GxAlert (example) allows data to flow
across the health system
GeneXpert
SMS
Email
Computer
App
Other Systems:
e-TB Manager
DHIS2
• Connects diagnostic devices
• Collects custom data
• Sends alerts, notifications,
and reports
• Monitors and manages
cartridge inventory
• Records service, warranty,
and maintenance events
• Integrates with other
health systems
© SystemOne LLC, 2016 All rights reserved.

13. “Connectivity” is no longer a single system – connectivity
is an ecosystem of platforms exchanging data.
What’s missing?
What’s missing?
• Interfaces governed by open standards
• Regulatory & governance framework for appropriate
sharing of data & information between systems
• Unique patient identification
• National ID
• Biometrics
• Innovative mechanisms to involve patient in
continuum of care
• Enhanced lab-clinic interface for translational
impact
© SystemOne LLC, 2016 All rights reserved.

14. QUESTIONS?
© SystemOne LLC, 2016 All rights reserved.
For any more information, please contact:
Brad Cunningham
VP, Implementation
SystemOne LLC
(m): +27 61 487 4693
bcunningham@systemone.id
www.systemone.id