SysFera-DS & the Décrypthon project

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Presentation of how SysFera-DS helps the Décrypthon project (the technological platform of the French Téléthon) to use geographically distributed clusters for genomics computations with a simple click.

Originally presented at Supercomputing 11 in Seattle, WA, 14-17 Nov.

Published in: Technology, Health & Medicine
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SysFera-DS & the Décrypthon project

  1. 1. Décrypthon research on rare diseases powered by Inria and SysFera technologies
  2. 2. Who are you guys?
  3. 3. SysFera <ul><li>2001: Research project from the Graal team (Inria/ENS) </li><ul><li>DIET: grid middleware </li></ul><li>2007: SysFera-DS used within the Décrypthon project </li><ul><li>Used in production 24/7/365 since then
  4. 4. Selected by IBM to replace Univa-UD </li></ul><li>2010: Creation of SysFera, INRIA spin-off
  5. 5. 2011: A team of 12 (R&D: 4 engineers and 5 PhD ) </li><ul><li>Supported by two experts from INRIA and ENS
  6. 6. SysFera-DS </li></ul></ul>
  7. 7. Helping cure muscular distrophy <ul>The Décrypthon Steering Commitee chose SysFera-DS starting on June 2007 for its qualities of robustness and modularity. It has been progressively implemented on the Décrypthon grid's ressources while ensuring a completely transparent and smooth transition for the users. </ul>Thierry Toursel Research Project Manager, AFM
  8. 8. The Décrypthon Project
  9. 9. Décrypthon Project history <ul><li>2001: Opération Décrypthon </li><ul><li>Objective: mapping the human proteome (560,000 proteins)
  10. 10. 75,000 internet users mobilized during 5 months
  11. 11. 1,710 years of computation </li></ul><li>2005: Décrypthon Program </li><ul><li>Foster research in the domains of interest for the AFM (the French association against myopathies), thanks to grid computing technologies </li></ul></ul>
  12. 12. 8 projects selected <ul><li>MS2PH: from Structural Mutation to the Phenotypes of Human Pathologies
  13. 13. Splicing deficiencies and genetic illnesses
  14. 14. Help Cure Muscular Dystrophy
  15. 15. SpikeOmatic: sorting action potentials
  16. 16. GEE: expressing the genes' evolution
  17. 17. Conformational sampling and docking
  18. 18. From functional genomics to the muscle
  19. 19. Transcriptional networks during myogenesis </li></ul>
  20. 20. The Décrypthon Grid
  21. 21. The Décrypthon grid <ul><li>production grid
  22. 22. using university computing centers
  23. 23. sharing resources between local users and users of the Décrypthon grid
  24. 24. access to resources
  25. 25. multiple interfaces: command line, Univa-UD
  26. 26. users are not computer scientists
  27. 27. integration of applications
  28. 28. dependence on batch schedulers </li></ul>
  29. 29. The Solutions
  30. 30. Web interface & distributed middleware
  31. 31. User and admin interface
  32. 32. One app - one page
  33. 33. User rights management
  34. 34. Statistics Number of results per hour Size of produced results per cluster
  35. 35. SysFera-DS does it all
  36. 36. SysFera-DS does it all <ul><li>Simple access to complex infrastructures
  37. 37. Advanced administration features </li><ul><li>User management and access control
  38. 38. Monitoring and reporting </li></ul><li>Integration to existing environments
  39. 39. Compatibility with many different resources
  40. 40. Non-intrusive, non-exclusive
  41. 41. Flexible, stable, reliable, performant </li></ul>
  42. 42. New web interfaces
  43. 43. New web interfaces
  44. 44. The power of the community
  45. 45. The power of the community <ul>SysFera-DS is open-source software... ...which means anyone can use it, share it, and contribute to it. </ul>
  46. 46. The power of the community <ul>Yes, it means you, too! So feel free to give it a try and become part of the community! ...and more! </ul>
  47. 47. Need more info? Ask the SysFera team. <ul>Visit us on Booth #4211 www.sysfera.com </ul>

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