Dengue fever ppt [autosaved]

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Dengue fever ppt [autosaved]

  1. 1.  DR.S.M. JOSHI MEDICAL OFFICER AND FACULTY MEMBER H.F.W.T.C.THANE
  2. 2.  Dengue fever is Caused by Virus spread by Aedes Egypti mosquitoes . Globally 2.5-3billion people are estimated to be at risk of infection with Dengue Diseases. It mainly affects children. The case fatality ranges from <1%- 1%(average5%) It is characterized by Fever, headache, muscle and joint pains, rash, nausea ,and vomiting. some infection results in dengue heamorraghagic fever can threaten patient’s life.
  3. 3.  DF and DHF are caused by four dengue viruses-DEN 1, DEN2, DEN3, DEN4which are closely related antigenically. Infection with one serotype provides life long immunity to that virus but not to others. Dengue viruses are maintained in urban transmission cycle in tropical and subtropical areas . Dengue viruses are transmitted from person to person by Aedes mosquitoes of the subgenus stegomyia .
  4. 4.  Ae. Aegypti breeds entirely in domestic man made water receptacles found in and around household, construction sites, factories, coconut shells, over head tanks ,septic tanks. Under the optimal conditions the life cycle of aquatic stage of the Ae. Aegypti can be short as seven days. Female of Ae. Aegypti is highly anthrofillic with two periods of biting activity several hours after daybreak and in the afternoon several hours before dusk.
  5. 5.  Ae. Aegypti prefer rest in dark,humid,secluded places inside houses,or buildings,bedrooms,closets, bathrooms,kitchen. Secondary dengue infection is a risk factor for DHF. Viremia is usually present at the time of or just before the onset of symtoms and lasts on average of five days after the onset of illness. Transmission Cycle Female mosquito bite for meal person with febrile illness mosquito infected transmission in another person onset of disease .
  6. 6.  Pathphysiological changes occur mainly in following two manners. 1) Plasma Leakage:-Increased vascular permeability resulting in plasma leakage,hypovolemiaand shock.DHF appers unique is that selective leakage of plasma into pleura and peritoneal cavities.The period of leakage is short-24-48 hours. 2) Heamorrahgic manifestations:-Abnormal heamostasis due to vasculopathy,thrombocytopenia, coagulopathy leading to various ) heamorrahgic manifestations. Clinical manifestations:- depends on age,immune status of host,and the virus strain. In infants it may develop as simple febrile illness indistiguishable from other viral infections.
  7. 7.  DIAGNOSIS:-In acute DF episode Total WBC-Normal at onset of fever, leucopenia develops through the febrile period, Platelet Count:- usually normal Serum Biochemistry-Normal Liver Enzymes-may be elevated. In acute DHF episode:- Total WBC-leucopenia develops through the febrile period, Platelet Count:- Thrombocytopenia is constant finding in DHF< 1,00,000/cu/mmof blood is usually found between 5-8day of ilness. Heamoconcentration is constant finding in DHF Transient Albuminurea is sometimes observed. Occult Blood:- is often found in stools.
  8. 8.  Management of DF Fever:- Is mainly symptomatic and supportive. 1-bed rest in Acute phase. 2-Antipyretics and Analgesics for control of fever and pain 3-.oral fluid and electrolyte therepy for excessive sweating and vomiting. Management of DHF Fever:- Antipyretics and Analgesics for control of fever and pain simmilar as DF. oral fluid and electrolyte therapy for excessive sweating and vomiting. IV fluid therapy to control plasma loss and impending shock. like Iv Colloid, Crystalloid, blood transfusion
  9. 9.  THANK YOU FOR LISTENING.

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