Pancreatitis

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Pancreaitis

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  • Pancreatitis

    1. 1. Pancreatitis Sherry L. Knowles, RN, CCRN, CRNI Orlando Regional Medical Center Orlando Health Pancreatitis Can Be Fatal
    2. 2. Anatomy & Physiology <ul><li>The Pancreas secretes digestive enzymes into the duodenum via the pancreatic duct. </li></ul><ul><li>(Lipase, Amylase, Trypsin) </li></ul><ul><li>The Pancreas also secretes bicarbonate, water, and lytes into the duodenum. </li></ul><ul><li>The Pancreas produces and secretes insulin as needed. </li></ul>
    3. 3. Definition of Pancreatitis <ul><ul><li>Inflammation of the pancreas associated with autodigestion </li></ul></ul><ul><ul><li>An autodigestive process resulting from premature activation of pancreatic enzymes. </li></ul></ul><ul><ul><li>May be acute or chronic </li></ul></ul>
    4. 4. Physiology of Pancreatitis <ul><ul><li>Inactive pancreatic enzymes are activated outside of the duodenum </li></ul></ul><ul><ul><li>The swelling pancreas causes fluids to shift into the retro peritoneum and bowel </li></ul></ul><ul><ul><li>Fluid shifts can cause severe hypovolemia and hypotension </li></ul></ul>
    5. 5. Causes of Pancreatitis <ul><li>Alcoholism </li></ul><ul><li>Biliary Disease </li></ul><ul><li>Infections </li></ul><ul><li>Hyperparathyroidism </li></ul><ul><li>Hypertriglyceridemia </li></ul><ul><li>Hypercalcemia </li></ul><ul><li>Peptic Ulcer Disease </li></ul><ul><li>Cystic Fibrosis </li></ul><ul><li>Vascular Disease </li></ul><ul><li>Multiple Drugs </li></ul>
    6. 6. Signs & Symptoms of Pancreatitis <ul><li>Abdominal Pain </li></ul><ul><li>Nausea & Vomiting </li></ul><ul><li>Abdominal Distention </li></ul><ul><li>Jaundice </li></ul><ul><li>Malnutrition </li></ul><ul><li>Hematemesis </li></ul><ul><li>Grey Turner’s Sign </li></ul><ul><li>Cullen’s Sign </li></ul><ul><li>Elevated Amylase, Lipase, LDH, </li></ul><ul><li>AST, WBC’s BUN, and Glucose </li></ul>
    7. 7. Complications of Pancreatitis <ul><li>Hypocalcemia </li></ul><ul><li>Hypotension </li></ul><ul><li>Acute Tubular Necrosis </li></ul><ul><li>DIC </li></ul><ul><li>Obstructive Jaundice </li></ul><ul><li>Erosive Gastritis </li></ul><ul><li>Paralytic Ileus </li></ul><ul><li>Pseudocyst or Abscess </li></ul><ul><li>Bowel Infarction </li></ul><ul><li>Internal Bleeding </li></ul><ul><li>Fat Necrosis </li></ul><ul><li>Pleural Effusion </li></ul><ul><li>Pulmonary Infiltrates </li></ul><ul><li>Hypoxemia </li></ul><ul><li>Atelectasis </li></ul><ul><li>ARDS </li></ul><ul><li>Pericardial Effusion </li></ul><ul><li>Mediastinal Abscess </li></ul><ul><li>Hyperglycemia </li></ul><ul><li>Hypertriglyceridemia </li></ul><ul><li>Encephalopathy </li></ul>
    8. 8. Treatment of Pancreatitis <ul><li>Stabilization: Correct Fluid And Electrolyte Status </li></ul><ul><li>Respiratory Support (as needed) </li></ul><ul><li>Control Pain (Demerol) </li></ul><ul><li>NG Tube (NPO) </li></ul><ul><li>TPN (Restricted Diet) </li></ul><ul><li>Monitor For Complications </li></ul><ul><li>Monitor Blood Sugar </li></ul><ul><li>Drug Therapies (Somatostatin, Anticholinergics) </li></ul><ul><li>Watch For Signs Of Infection </li></ul><ul><li>Pray </li></ul>
    9. 9. Pancreatitis Can Be Fatal THE END

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