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Rapid Sequence Intubation      Steven Podnos MD
RSI• Definition: Using drugs that make emergent  intubation of conscious patients safer and  more controlled• Process: Use...
The Seven Ps of RSI•   Preparation•   Preoxygenation•   Pre treatment•   Paralysis•   Protection and Positioning•   Placem...
Preparation• Cardiac Monitor, O2 sat, IV access, BP monitor• Suction, all meds ready and drawn up, crash  cart, bag valve ...
Pre-oxygenation• Done to avoid using Bag Valve mask  ventilation• High flow O2 (usually at least 3-5 minutes)  given to “w...
Pretreatment• In some cases, Lidocaine 1mg/kg IV or  Fentanyl is given to reduce the physiologic  increase in ICP in patie...
Paralysis and Induction• RSI is designed to achieve paralytic and  sedated state within one minute. No titration-  use who...
Ideal Drugs• Should have duration of very few minutes in  case intubation is not successful.• Sedatives used: Etomidate, M...
Sedative Drugs• Etomidate-hemodynamically neutral,• 0.3mg/kg bolus• Midazolam-0.2mg/kg bolus, does often cause  hypotensio...
Protection with Positioning• Avoid Bag Mask Ventilation• Cricoid pressure very controversial
Placement with proof• MUST have EtCO2 proof , either colorimetric  or quantitative (monitor)• In cardiac arrest may not se...
Postintubation Management• Fix the ETT location• CXR for depth of tube• Fluid bolus for transient hypotension
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Rapid sequence induction

  1. 1. Rapid Sequence Intubation Steven Podnos MD
  2. 2. RSI• Definition: Using drugs that make emergent intubation of conscious patients safer and more controlled• Process: Use of a sedative /hypnotic agent to induce relaxation/sleepiness/amnesia followed by a neuromuscular blocker to stop any resistance to the intubation process
  3. 3. The Seven Ps of RSI• Preparation• Preoxygenation• Pre treatment• Paralysis• Protection and Positioning• Placement with Proof• Post intubation management
  4. 4. Preparation• Cardiac Monitor, O2 sat, IV access, BP monitor• Suction, all meds ready and drawn up, crash cart, bag valve mask• Difficult airway assessment and alternate airways available
  5. 5. Pre-oxygenation• Done to avoid using Bag Valve mask ventilation• High flow O2 (usually at least 3-5 minutes) given to “wash out” nitrogen and increases body oxygen stores. Can extend time allowed without ventilation for several minutes
  6. 6. Pretreatment• In some cases, Lidocaine 1mg/kg IV or Fentanyl is given to reduce the physiologic increase in ICP in patients with head injuries
  7. 7. Paralysis and Induction• RSI is designed to achieve paralytic and sedated state within one minute. No titration- use whole doses of drugs
  8. 8. Ideal Drugs• Should have duration of very few minutes in case intubation is not successful.• Sedatives used: Etomidate, Midazolam (Versed), Propofol• Paralytics used: Succinylcholine (Anectine)
  9. 9. Sedative Drugs• Etomidate-hemodynamically neutral,• 0.3mg/kg bolus• Midazolam-0.2mg/kg bolus, does often cause hypotension• Propofol-2mg/kg bolus, may cause hypotension and CPP. Bronchodilator
  10. 10. Protection with Positioning• Avoid Bag Mask Ventilation• Cricoid pressure very controversial
  11. 11. Placement with proof• MUST have EtCO2 proof , either colorimetric or quantitative (monitor)• In cardiac arrest may not see CO2 production. Positive CO2 for six breaths is definitive evidence of proper airway placement.• Clinical and CXR evaluation is not definitive for placement
  12. 12. Postintubation Management• Fix the ETT location• CXR for depth of tube• Fluid bolus for transient hypotension
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