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2018 StartUp Health Insights Global Digital Health Funding Report 2018 Midyear

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The first half of 2018 has brought an increase in deal volume and a total of $6.1B invested in digital health companies across the globe - showing a heightened confidence in the sector.

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  • Here is the list:BioIQ Santa Barbara, CA $26,500,000 Intouch Technologies Santa Barbara, CA $21,000,000 Embodied, Inc. Pasadena, CA $20,000,000 Heal Santa Monica, CA 20000000 Embodied, Inc. Pasadena, CA $12,392,076 mPulse Mobile Encino, CA 11,000,000 Intouch Technologies Santa Barbara, CA $8,620,000 Casetabs Santa Monica, CA 6000000 Tagnos, Inc.  Irvine, CA $5,819,054 Care3, Inc.  Los Angeles, CA $3,705,425 Eyenuk Woodland Hills, CA $3,000,000 Casetabs Santa Monica, CA $2,269,916 MindMate Inc.  Santa Monica, CA $1,257,874 MD Insider, Inc.  Santa Monica, CA $1,023,332 PatientFi, LLC Irvine, CA $1,000,180 PARALLAX HEALTH SCIENCES, INC. Santa Monica, CA $600,000 Alert Mobile Diagnostics, LLC Laguna Hills, CA $575,000 Evid Science, Inc.  Los Angeles, CA $500,000 WiseCare Los Angeles, CA $325,000 Eyedaptic Laguna Niguel, CA $275,000
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  • Friends at StartUp Health: you are always under-reporting the industry's performance in Greater Los Angeles. By our count, we had 20 deals totaling more than $145 million from Jan 1 to June 30, 2018.
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2018 StartUp Health Insights Global Digital Health Funding Report 2018 Midyear

  1. 1. © 2018 StartUp Health, LLC STARTUP HEALTH INSIGHTS Global Digital Health Funding Report 
 Data through June 30, 2018 Report is inclusive of publicly available seed, venture, corporate venture, and private equity funding. Sign up to receive weekly funding insights at startuphealth.com/insider. 2018 Midyear TM
  2. 2. ABOUT STARTUP HEALTH Pages Topic 3 ………………………………………….…… Health Moonshots 4 ………………………………………….…… 2018 Midyear Summary 5-10 ………………………………………….…… Deals and Funding 11-15 ………………………………………….…… Global Funding 16-18 ………………………………………….…… Investors 19-23 ………………………………………….…… Segment Detail 24-27 ………………………………………….…… Health Transformers 28 ………………………………………….…… Methodology In 2011, StartUp Health introduced a new model for transforming health by investing in a global army of coachable entrepreneurs who are committed to achieving health moonshots. With the world’s largest digital health portfolio (more than 240 companies spanning six continents, 20 countries, and 70+ cities), StartUp Health is mobilizing this rapidly growing army along with the world’s ‘batteries included’ leaders, innovators, and investors to achieve 10 Health Moonshots, with a 25-year mission to improve the health and wellbeing of everyone in the world. Learn more about how to join the movement and support Health Transformers at startuphealth.com. StartUp Health Insights TM Contributors 2 Jennifer Hankin Mark Liber Anne Dordai Nicole Kinsey Tara Salamone Polina Hanin Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC Liz Tucci
  3. 3. 1 Access to Care Moonshot Delivering quality care to everyone, regardless of location or income 2 Cost to Zero Moonshot Radically reducing the cost of care by a factor of a million 3 Cure Disease Moonshot Curing disease using data, technologies, and personalized medicine 4 End Cancer Moonshot Ending cancer as we know it 5 Women’s Health Moonshot Prioritizing women’s health, including preventive care and new research 6 Children’s Health Moonshot Ensuring every child has access to quality care, regardless of economic status 7 Nutrition & Fitness Moonshot Providing access to a healthy environment and supporting an active lifestyle 8 Brain Health Moonshot Unlocking the mysteries of the brain to improve health, wellness, and mental health 9 Mental Health & Happiness Moonshot Connecting mind, body, and spirit in the pursuit of happiness 10 Longevity Moonshot Adding 50 healthy years to every human life ON A MISSION TO ACHIEVE 10 HEALTH MOONSHOTS At StartUp Health we believe that with the right mindset, a moonshot vision, and the spirit of an entrepreneur, anything is possible. That's why we've brought together a new generation of entrepreneurs, investors, industry leaders, and government organizations who are working on bold missions to transform health. Here are the 10 Health Moonshots around which StartUp Health has focused its efforts. Each one can improve the wellbeing of at least one billion people. 3Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC
  4. 4. 1 Late-StageInvestmentContinuestoGrow 4 HugeInternationalDeals Early stage deals still dominate the market volume, but we saw more series B deals (as a percentage of total deals) – and larger series C and D deals – than ever. This resulted in a record first half, with over $6B total raised. Three of the top ten deals of the quarter involved companies based outside the U.S. – Toronto, London, and Zhenjiang. Zhenjiang makes its debut on our list of international hubs, joining Stockholm and Tel Aviv as a top city to watch. 2 PowertothePatient 5 China’sFundingSurge Patient empowerment sits at the top as the most funded function (a company’s main activity/value driver), and patients are the second most funded end user. Six out of eight top investors made major investments in patient empowerment as well. China is proving to be the most consistent and well-funded country in the international digital health market, with funding totals in Beijing rivaling major U.S. cities. With well-resourced players like Ping An committed to digital health investments, we expect this trend to continue. 3 Less Time Between Early Raises 6 TopInvestorsCastaWiderNet While seed and series A deals as a percentage of all deals decreased, average time between these two rounds has also decreased. Nine of this year’s top ten investors are making deals at multiple stages, and five are making deals at every stage. More investors are keeping an eye out for transformative technology and growth potential, regardless of deal size. Deal volume continued to trend upwards through the first half of 2018, with a total of 414 deals. That's approximately a 20% increase over the first half of 2017. International investments reached hundreds of millions of U.S. dollars for the first time, and these funds are funneling to a broader range of cities than ever before. Globally, investors are on track to nearly double their 2017 investments, demonstrating their long-term commitment as well as the overall growth potential in the market. Together these trends confirm a heightened confidence in the sector. 4 2018 MIDYEAR SUMMARY DEALS & FUNDING GLOBAL INVESTORS Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC SEGMENT DETAIL
  5. 5. 2010 2011 2012 2013 2014 2015 2016 2017 2018 (YTD) Q1 Q2 Q3 Q4 153 283 476 647 608 568 684 852 414 FUNDING SNAPSHOT: YEAR OVER YEAR 5 Deal Count $1.9B $2.1B $1.9B $891M $591M $516M$424M $8.2B $6.2B $7.1B $2.9B $2.3B $2.0B $1.2B $11.7B $3.8B Deal volume in 2018 is trending upwards, with 414 deals compared to 344 at this point last year. This is the largest deal volume we’ve seen in the first half of any year since we began tracking funding in 2010.* DEALS & FUNDING GLOBAL INVESTORS $3.1B $6.1B (YTD) Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC *If Grail’s $914M raise in H1 2017 is removed from overall count, then the $6B raise this year would make it the largest half to date. SEGMENT DETAIL
  6. 6. $.0B $.5B $1.0B $1.5B $2.0B Jan Feb Mar Apr May Jun Jul Aug Sep Oct Nov Dec 2014 2015 2016 2017 2018 (YTD) 6 Funding includes Grail’s $914M Series B FUNDING SNAPSHOT: MONTHLY COMPARISON With exception of May 2017 and its $2.4B in funding, 2018 is showing very strong month-over-month growth over previous years. Specifically, while there was a customary dip in funding in February and June, 2018 has seen a steady 21% growth month over month. Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC DEALS & FUNDING GLOBAL INVESTORS SEGMENT DETAIL
  7. 7. FUNDING VELOCITY: FIVE THRIVING FUNCTIONS 7 The time between seed and series A funding has sped up, with the average time between rounds falling by 2.5 months to 15.7 months. Companies addressing admin workflow issues have proven to be the fastest, with new rounds taking just over a year to raise. Companies addressing clinical workflow are taking almost six months longer on average to raise a series A. .0% .05% .1% .15% 0 8.333 16.667 25 33.333 41.667 50 Number of Months From Seed to Series A (2013-2018 Data) Clinical Workflow 18.7 mo Patient Empowerment 16.4 months Wellness 16.1 months Average Time From Seed to A Round 15.7 months Admin Workflow 13.0 months Personalized Health 18.5 months Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC Distribution DEALS & FUNDING GLOBAL INVESTORS SEGMENT DETAIL
  8. 8. 2010 2011 2012 2013 2014 2015 2016 2017 2018 0% 25% 50% 75% 100% Seed Series A Series B Series C Series D Series E Series F + G + H 30% 29% 10%25% *Deal count only includes seed though series H rounds and does not include venture rounds, accelerator funding, or growth equity. Deal Count* 119 220 287 435 396 326 385 DEAL ACTIVITY BY STAGE 487 8 Seed and series A deals, historically dominating deal volume by percentage, are showing a 5% drop at the midyear mark. The percentage of series B deals has made up the difference, with a 5% increase over 2017 levels. 236 Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC DEALS & FUNDING GLOBAL INVESTORS SEGMENT DETAIL
  9. 9. Company Round Total Function 1 $300M Biometric Data Acquisition 2 $240M Clinical Workflow 3 $200M Biometric Data Acquisition 4 $165M Insurance 5 $146M Admin Workflow 6 $115M Research 7 $110M Insurance 8 $105M Population Health 9 $100M Education / Content 9 $100M Patient Empowerment Grail closed another round this year, topping our midyear report for a second time. Nevertheless, the list is more diverse than ever, representing eight out of ten functions – a company’s main activity/value driver – from insurance to population health. THE 10 LARGEST DEALS OF 2018 (YTD) 9Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC DEALS & FUNDING GLOBAL INVESTORS SEGMENT DETAIL
  10. 10. Region 2018 YTD Deal Count 2017
 Deal Count 1 SF Bay Area 77 151 2 New York City 46 82 3 Boston 24 32 4 Los Angeles 9 21 5 Austin 7 15 5 Chicago 7 26 7 Seattle 5 17 7 Baltimore 5 10 7 Philadelphia 5 14 7 Minneapolis 5 11 While many metro areas on our list are equalling their 2017 pace, Boston and Phoenix showed strong growth in the first half of 2018. San Francisco, New York, and Boston have dominated in funding deals and dollars, accounting for 78% of total deals (146) and 81% of total dollars invested ($3.32B). $117M $634M $498M $56M $2.2B San Francisco Bay Area Denver Phoenix New York City Boston $165M Chicago $137M Minneapolis / St. Paul (5 Deals) (4 Deals) (76 Deals) (4 Deals) (7 Deals) (46 Deals) (24 Deals) Austin $107M (7 Deals) THE MOST ACTIVE U.S. METRO AREAS OF 2018 (YTD) 10 $93M Baltimore (5 Deals) $109M Los Angeles (9 Deals) * Map shows top 10 metro areas by total dollars (USD) Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC DEALS & FUNDING GLOBAL INVESTORS SEGMENT DETAIL
  11. 11. Region 2018 YTD Deal Count 2017
 Deal Count 1 London 11 25 2 Bengaluru 10 20 3 Beijing 9 17 3 Stockholm 9 16 5 Toronto 8 20 5 Tel Aviv 8 20 5 New Delhi 8 10 8 Mumbai 6 10 8 Singapore 6 9 10 Shanghai 5 3 Beijing continues to be the epicenter of digital health in China, accounting for 40% of Chinese investments over the last five years. In 2018, however, China is starting to see investor attention elsewhere. While four of the top ten international metro hubs are Chinese cities, Beijing accounts for just 27%. INTERNATIONAL METRO HUBS OF 2018 (YTD) China 11 $173M $141M $75M $78M $171M Toronto London Paris Beijing Hangzhou $91M Bengaluru $116M Tel Aviv (11 Deals) (8 Deals) (4 Deals) (10 Deals) (9 Deals) (1 Deal) Zhenjiang $100M (1 Deal) $105M Shanghai (5 Deals) $69M Stockholm (9 Deals) (8 Deals) * Map shows top 10 metro areas by total dollars (USD) Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC DEALS & FUNDING GLOBAL INVESTORS SEGMENT DETAIL
  12. 12. THE TOP 10 INTERNATIONAL DEALS OF 2018 YTD Company Total Raised Metro Area 1 $146M Toronto 2 $115M London 3 $100M Zhenjiang 4 Helian Health $75M Hangzhou 5 $66M Stockholm 6 (Yaoshibang) $65M Guangzhou 6 $61M Beijing 6 $55M Leeds 9 $51M Bengaluru 10 $49M Dublin New digital health innovation hubs continue to pop up across the globe, with Zhenjiang, China, joining mainstays Toronto and London. Thirty percent of these international top deals were also on the overall top deals list including the major funding rounds from the U.S. Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC 12 DEALS & FUNDING GLOBAL INVESTORS SEGMENT DETAIL
  13. 13. INTERNATIONAL SPOTLIGHT: CHINA $36M Chengdu (2 Deals) $105M Shanghai (5 Deals) Funding Facts: • $523M has been invested in mainland China this year across 20 total deals. • Beijing dominated funding for digital health in China in 2016 & 2017, averaging $600M over those years. • Of total funding in China, only $141M was invested in Beijing in 2018. Big money is starting to spread into cities such as Chengdu, Hangzhou, Zhenjiang, Shenzhen, and Guangzhou as the country’s ecosystem strengthens. $0M $150M $300M $450M $600M $750M 2013 2014 2015 2016 2017 $21M $105M $45M $550M $651M Beijing Funding 13 $141M $75M Beijing Hangzhou (9 Deals) (1 Deal) Zhenjiang $100M (1 Deal) $65M Guangzhou (1 Deal) Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC *Map contains funding for 2018 YTD DEALS & FUNDING GLOBAL INVESTORS SEGMENT DETAIL
  14. 14. INTERNATIONAL SPOTLIGHT: FINLAND $77M Helsinki (29 Deals) $2M Tampere (3 Deals) $8M Espoo (2 Deals) Funding Facts: • $17M has been invested in Finland this year across six total deals (five in Helsinki), 17% of Finland’s total funding since 2013 ($102M). • Helsinki has historically carried Finland in terms of deal count, averaging nine deals/year since 2016, and funding. $43M was invested here in 2017. • 2017 saw the first deal in Tampere, and we have another three in 2018. $0M $10M $20M $30M $40M $50M 2013 2014 2015 2016 2017 $11M $10M $5M $15M $43M Finland Funding 14 $15M Oulu (2 Deals) Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC *Map contains funding from 2013-2018 YTD DEALS & FUNDING GLOBAL INVESTORS SEGMENT DETAIL
  15. 15. Firm 2018 YTD Deals* 2017 Midyear Deals* Stage Early Mid Late 1 10 4 2 9 6 3 8 4 4 6 0 5 5 1 5 5 4 5 5 3 5 5 2 5 5 0 THE MOST ACTIVE INVESTORS OF 2018 (YTD) 15 *Deal count excludes accelerator rounds The top investors all made more investments in the first half of this year than during the same period in 2017. Polaris makes our list of most active investors for the first time, while Greylock Partners makes a reappearance after being out of the top ten for almost four years. Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC DEALS & FUNDING GLOBAL INVESTORS SEGMENT DETAIL
  16. 16. Khosla Ventures is the most active investor so far this year and has diversified its portfolio across seven of ten functions (defined as a company’s main activity/value driver). Patient empowerment is the company function that has had the most interest from the most active VCs. Investors THE TOP INVESTORS OF 2018 BY FUNCTION 16 Research Biometric Data Acquisition Personalized Health Admin Workflow Patient Empowerment Population Health Wellness Clinical Workflow Insurance Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC DEALS & FUNDING GLOBAL INVESTORS SEGMENT DETAIL
  17. 17. 0 33 66 99 132 165 2010 2011 2012 2013 2014 2015 2016 2017 2018 YTD 2 3 4 5 6+ 1 There have been 754 unique investors in digital health so far in 2018, compared to 583 at midyear 2017. If historical trends continue, those 754 unique investors will more than double by the end of the year. 174 284 299 488 611 647 921 1,247 757 InvestorCount # of Deals by Investor TOTAL INVESTORS YEAR OVER YEAR Total Unique Investors Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC 17 DEALS & FUNDING GLOBAL INVESTORS SEGMENT DETAIL
  18. 18. Function Total Raised Deal Count Avg. Deal Size Median Deal Size 1 Patient Empowerment $1.04B 104 $11.8M $3.4M 2 Biometric Data Acquisition $1.02B 36 $31.0M $10.5M 3 Clinical Workflow $810M 74 $13.3M $5.4M 4 Admin Workflow $752M 63 $14.5M $4.8M 5 Wellness $542M 41 $14.3M $9.0M 6 Population Health $491M 19 $28.9M $20.0M 7 Research $484M 23 $22.0M $12.8M 8 Insurance $442M 9 $49.2M $28.3M 9 Personalized Health $423M 37 $12.8M $8.0M 10 Education $133M 8 $13.2M $16.2M THE MOST ACTIVE FUNCTIONS OF 2018 (YTD) 18 Nearly every function (a company’s main activity/value driver) was spearheaded by a $100M deal, so it’s no surprise to see average deal sizes largely diverging from median deal sizes. Despite not having any companies in the largest deals to date this year, population health has attracted consistently large deals with a median deal size of $20M. Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC DEALS & FUNDING GLOBAL INVESTORS SEGMENT DETAIL
  19. 19. Application* Total Raised Deal Count Average Deal Size Median Deal Size 1 Diagnostic/Screening $979M 42 $23.3M $10.8M 2 Genomics $959M 17 $56.4M $31.8M 3 Clinical Decision Support $683M 33 $20.7M $6.6M 4 Care Coordination $668M 44 $15.2M $6.6M 5 Operational Management $518M 58 $8.9M $2.8M THE MOST ACTIVE APPLICATIONS OF 2018 (YTD)* 19 StartUp Health Company Spotlights: * The application is the use cases for the Company's technology. Deals may be included in multiple applications. For pharmaceutical companies that need a low cost, easy- to-use diagnostic for endometriosis, Oratel Diagnostics' saliva-based diagnostic technology can identify endometriosis within 20 minutes. Clinical Decision Support For providers who need to improve quality outcomes, @Point of Care is a clinical decision support tool that delivers clinical knowledge support and allows patients to share data with their clinician. Diagnostics Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC DEALS & FUNDING GLOBAL INVESTORS SEGMENT DETAIL
  20. 20. End User Total Raised Deal Count Average Deal Size Median Deal Size 1 Provider $2.9B 173 $16.6M $6M 2 Patient $2.1B 163 $13.0M $4.8M 3 Consumer $1.6B 119 $13.8M $7.5M 4 Pharma $540M 18 $30.0M $11.0M 5 Research $492M 26 $18.9M $10.0M THE MOST ACTIVE END USERS OF 2018 (YTD)* 20 *The end user is the organization or individual who benefits from the Company's value. Deals may be included in multiple end user types. StartUp Health Company Spotlight: For nearly 80% of the global population that struggles with vitamin D insufficiency, SOLIUS is a medical experience that uses advanced light science to strengthen the body’s systems by stimulating the production of critical hormones and peptides, including vitamin D. Pharma For pharmaceutical companies developing precision medicine solutions, Sanguine partners with patients to create Data-Integrated Patient Communities and uses AI to match patients to clinical trials faster. Consumer Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC DEALS & FUNDING GLOBAL INVESTORS SEGMENT DETAIL
  21. 21. Specialty Total Raised Deal Count Average Deal Size Median Deal Size 1 Specialty Agnostic $1.3B 108 $11.9M $4.2M 2 Administrative $908M 45 $20.2M $9.4M 3 Oncology $636M 12 $53.0M $43.5M 4 Genomics $634M 9 $70.4M $32.5M 5 Cardiology/ Cardiovascular $338M 13 $26.0M $5.5M THE MOST ACTIVE SPECIALTIES OF 2018 (YTD)* 21 *The speciality is the branch of medicine or disease the Company addresses. Deals may be included in multiple speciality types. StartUp Health
 Company Spotlight: For doctors looking to detect heart disease, the world’s #1 cause of death and disability, eko.ai’s machine learning based software eliminates the manual processes and the expensive hardware. Oncology For employers that are spending millions of dollars per year on cancer-related medical claims, MyPeople Health's care management platform drives preventive and proactive care among employees - reducing claim costs and lost productivity. Cardiology Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC ** The “Specialty Agnostic” tag represents companies such as symptom checkers that focus on all specialties, rather than specific ones. DEALS & FUNDING GLOBAL INVESTORS SEGMENT DETAIL
  22. 22. Technology Total Raised Deal Count Average Deal Size Median Deal Size 1 Web App $2.2B 185 $12.1M $4.0M 2 Mobile App $1.3B 131 $9.9M $5.0M 3 Analytics Tool $1.0B 79 $13.2M $6.0M 4 Genetic Sequencing $828M 12 $69.0M $33.0M 5 Hardware / Medical Device $590M 39 $15.1M $12.1M THE MOST ACTIVE TECHNOLOGIES OF 2018 (YTD)* 22 * The technology is the delivery mechanism of a Company's value. Deals may be included in multiple technology types. StartUp Health Company Spotlight: Hardware / Medical Device Web App For medical providers in Latin America who live by paper records, Omnia Salud is an integrated billing, scheduling, and EHR solution platform that fully digitizes their practice. For arthroscopic surgeons who struggle with cumbersome wires and outdated technology, ArthroFree is the world’s first fully wireless, minimally invasive camera that seamlessly integrates into existing OR workflows. Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC DEALS & FUNDING GLOBAL INVESTORS SEGMENT DETAIL
  23. 23. STARTUP HEALTH COMPANY MERGERS & ACQUISITIONS 23 September 2017 acquired by January 2017 acquired by October 2016 acquired by July 2016 acquired by May 2016 acquired by March 2016 acquired by June 2016 acquired by May 2015 acquired by March 2014 acquired by October 2013 acquired by July 2013 acquired by April 2017 merged with October 2016 merged with October 2016 acquired by December 2017 merged with December 2017 acquired Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC April 2018 acquired by June 2018 acquired by June 2018 acquired
  24. 24. STARTUP HEALTH’S GROWING ARMY 24Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC
  25. 25. 25 ARMY OF HEALTH TRANSFORMERS BY HEALTH MOONSHOT Women’s Health Access to Care Cure Disease Longevity Cost to Zero Nutrition & Fitness Mental Health & Happiness End Cancer Children’s Health Brain Health Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC
  26. 26. 26 JOIN THE MOVEMENT Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC Meet the entrepreneurs transforming health on StartUp Health HQ. Join today at hq.startuphealth.com
  27. 27. Sectors: • We have a broad view of digital health and believe that the current trend is a cross-pollination of technology and data with all aspects of health and healthcare. StartUp Health InsightsTM tracks companies that enable health, wellness and the delivery of care through data/analytics, sensors, mobile, internet-of-things, 3D printing, genomics, and personalized medicine. • StartUp Health tracks companies based on their Health Moonshot, function, applications, specialties, technology types, and end users. Investments in each of these tags are not mutually exclusive, as deals are tagged with multiple Moonshots, applications, specialties, end users, and technology types, based on the company’s focus. • These categorizations fall into The StartUp Health Moonshot ID to help define each company: • To achieve the MOONSHOT in SPECIALTY, COMPANY provides END USER with a FUNCTION TECHNOLOGY for APPLICATIONS. Stage of Funding: • StartUp Health InsightsTM records only publicly available data on cash for equity investments as the cash is actually received by the company. StartUp Health InsightsTM is inclusive of accelerator, pre-seed, seed, venture, corporate venture, and private equity funding. • Early stage: The company has raised a Seed or Series A round • Mid stage: The company has raised a Series B or Series C round • Late stage: The company has raised a Series D or other growth equity round • StartUp Health also tracks accelerator rounds and other financings into privately-held entities (e.g. “unnamed” venture rounds, strategic investments, growth equity, and private equity). • In tabulating deal activity by stage we excluded rounds not clearly associated with a specific stage. Sources: • Funding data is from StartUp Health InsightsTM, the most comprehensive funding database for digital health, and managed by the StartUp Health team. Information, data, and figures represent only publicly available data. • Data for acquisitions slide was provided by a range of sources including StartUp Health InsightsTM, CrunchBase, AngelList, and news reports. • StartUp Health works to ensure that the information contained in the StartUp Health InsightsTM Report has been obtained from reliable sources. However, StartUp Health cannot warrant the ultimate validity of the data obtained in this manner. All data is subject to verification with the venture capital firms and/or the investee companies. Results are updated periodically. Therefore, all data is subject to change at any time. • If you find an error please let us know so we can correct it. This report is provided for informational purposes and was prepared in good faith on the basis of public information available at the time of publication without independent verification. StartUp Health does not guarantee or warrant the reliability or completeness of the data nor its usefulness in achieving any particular purposes. StartUp Health shall not be liable for any loss, damage, cost, or expense incurred by reason of any persons use or reliance on this report. This report is a proprietary aggregation of publicly available data and shall not be forwarded or reproduced without the written consent of StartUp Health. METHODOLOGIES 27Source: StartUp Health Insights | startuphealth.com/insights Note: Report based on public data through 6/30/18 on seed (incl. accelerator), venture, corporate venture, and private equity funding only. © 2018 StartUp Health LLC

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