Cholesterol Management

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Cholesterol Management, presented by Christian Zellner MD, Cardiology, Springfield Clinic.

Originally presented at Springfield Clinic Me 1st Women's Health Event, May 2010 - All information and images provided by presenter.

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Cholesterol Management

  1. 1. Love your Heart: Cholesterol Management Christian Zellner, MD Department of Cardiology
  2. 2. Love Your Heart <ul><li>Why should you care? </li></ul><ul><li>At what age do I need to start? </li></ul><ul><li>What is cholesterol ? </li></ul><ul><li>How can I lower my cholesterol? </li></ul>
  3. 3. Why Should You Care?
  4. 4. Heart Disease in Women <ul><li>Leading cause of death </li></ul><ul><li>Women are 4 times more likely to die from heart disease than men </li></ul><ul><li>Prevention can substantially reduce risk </li></ul><ul><li>Diet is key </li></ul><ul><li>Consider drug side-effects </li></ul>
  5. 5. When Do I Need to Start? <ul><li>Get started in your 20’s </li></ul><ul><li>Step it up in your 30’s </li></ul><ul><li>Get serious in your 40’s </li></ul><ul><li>Add medication when needed </li></ul>
  6. 6. Cholesterol <ul><li>Basic building block of Life </li></ul><ul><li>Our bodies contain 35 g of cholesterol </li></ul><ul><li>1,000 mg synthesized each day </li></ul><ul><li>About 300 mg taken up each day </li></ul>
  7. 7. Cholesterol <ul><li>Entirely derived from animal sources </li></ul><ul><li>Plants contain sterols </li></ul>
  8. 8. Cholesterol <ul><li>25% of cholesterol is made in the liver </li></ul><ul><li>Recycling via bile and GI tract </li></ul>
  9. 9. Cholesterol <ul><li>Konrad Bloch and Feodor Lynen shared the Nobel Prize in 1964 </li></ul><ul><li>Reduction in intake may increase internal production </li></ul>
  10. 10. Cholesterol <ul><li>Passive uptake of cholesterol from diet in the GI tract </li></ul><ul><li>Sterols actively returned into gut </li></ul>
  11. 11. Cholesterol <ul><li>What Makes Up Cholesterol? </li></ul><ul><li>Cholesterol </li></ul><ul><li>Triglycerides </li></ul>
  12. 12. Cholesterol <ul><li>What Makes Up Cholesterol? </li></ul><ul><li>HDL </li></ul><ul><li>LDL </li></ul><ul><li>VLDL </li></ul>
  13. 13. Cholesterol <ul><li>Gender-related Lipid Topics </li></ul><ul><li>Women have higher HDL </li></ul><ul><li>Estrogen therapy can cause elevated triglycerides </li></ul><ul><li>Risk of statins during pregnancy </li></ul>
  14. 14. Cholesterol <ul><li>What Affects LDL Cholesterol? </li></ul><ul><li>Diet: Saturated Fats </li></ul><ul><li>Obesity </li></ul><ul><li>Thyroid Disease </li></ul><ul><li>Lack of Exercise </li></ul><ul><li>Family Genes </li></ul>
  15. 15. Cholesterol <ul><li>What Affects HDL Cholesterol? </li></ul><ul><li>Obesity </li></ul><ul><li>Lack of Exercise </li></ul><ul><li>Family Genes </li></ul><ul><li>Smoking </li></ul><ul><li>Certain drugs </li></ul><ul><li>Diabetes </li></ul>
  16. 16. Cholesterol <ul><li>What Affects Triglycerides? </li></ul><ul><li>Obesity </li></ul><ul><li>Lack of Exercise </li></ul><ul><li>Family Genes </li></ul><ul><li>High Carb Diet </li></ul><ul><li>Certain drugs </li></ul><ul><li>Diabetes </li></ul>
  17. 17. What You Can Do: <ul><li>How Can I Lower My Cholesterol? </li></ul>
  18. 18. How Can I Lower My Cholesterol? <ul><li>Cut Back on Saturated Fats </li></ul>
  19. 19. How Can I Lower My Cholesterol?
  20. 20. How Can I Lower My Cholesterol? <ul><li>Add Phytosterols to Your Diet </li></ul><ul><li>Sesame and Olive Oil </li></ul><ul><li>Nuts (Almonds) </li></ul><ul><li>Wheat Bran </li></ul><ul><li>(Take Control, Benecol) </li></ul><ul><li>Synergy when taken with statins </li></ul>
  21. 21. How Can I Lower My Cholesterol?
  22. 22. Cholesterol Drugs: Statins <ul><li>Dr. Michael S. Brown and Dr. Joseph L. Goldstein received Nobel Price in1985 for discovery of HMG-CoA reductase </li></ul><ul><li>Inhibits cholesterol synthesis and increases LDL cholesterol uptake in liver </li></ul>
  23. 23. Cholesterol Drugs: Statins <ul><li>Lipitor </li></ul><ul><li>Crestor </li></ul><ul><li>Simvastatin </li></ul><ul><li>Pravastatin </li></ul><ul><li>Lovastatin </li></ul>
  24. 24. Cholesterol Drugs: Statins <ul><li>1,200mg twice daily </li></ul>
  25. 25. Cholesterol Drugs: Fish Oil <ul><li>1000mg to 3000mg DHA and EPA </li></ul>
  26. 26. Cholesterol Drugs: Krill Oil <ul><li>2000mg – 3000mg Krill Oil </li></ul>
  27. 27. Love Your Heart <ul><li>Eat Right </li></ul><ul><li>Exercise </li></ul><ul><li>Don’t Smoke </li></ul><ul><li>Know your Family History </li></ul><ul><li>Keep Regular Check-ups with your Doctor </li></ul>
  28. 28. Love Your Heart

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