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Basic research.ppt

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Basic research.ppt

  1. 1. Design research study •Study designs …(not exhaustive) •Case series •Cross-sectional •Case-control •Cohort: (Observational study) •Randomized controlled clinical trials Research study design is a framework, or the set of methods and procedures used to collect and analyse data on variables specified in a particular research problem.
  2. 2. The Next Step •Formally test the identified hypotheses in a research study •The study should follow a specific plan or protocol (the study design) •Study designs direct how the investigation is conducted and allows for the translation of a conceptual hypothesis into an operational one
  3. 3. Clinical Research • Research conducted on humans or human tissues that makes use of patient data. • Includes study of disease mechanisms, therapeutic interventions, epidemiology, and clinical trials. • Aimed at understanding human disease and improving human health. • Interaction between researchers and patient data is a key feature. Basic Scientific Research • Fundamental theoretical or experimental investigative research to advance knowledge without a specifically envisaged or immediately practical application. • It is the quest for new knowledge and the exploration of the unknown. • Takes many years for the results of basic research to find some practical utility. • Output based research through research articles and patents
  4. 4. Basic and Clinical Research are Interdependent Translation from basic science to human studies Translation of new knowledge into clinical practice Basic Research Clinical Research Improved Health Adapted from Sung et al. (2003) JAMA, 289, 1278-89. Copyright © (2003) American Medical Association. All Rights reserved.
  5. 5. “Disappointment is when a beautiful hypothesis is destroyed by an ugly fact” “Sir, Isaac Newton” Thank you…

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