Lab Informatics 09 Se

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Evolution of an ELN: Lessons learned from 5 years of
ELN use at Merck
• Use of ELN for Green Science at Eli Lilly and
Company
• Biology ELN Applications to Pharmacokinetics
• Cross-Disciplinary Integration Via Comprehensive
Informatics Environments, A Case Study In Bridging
Discovery And Pre-Clinical Development
Workflows
• Breaking Data Silos To Enable Integrated Safety
Assessment In Early Drug Discovery

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Lab Informatics 09 Se

  1. 1. Register by Feb. 27, 2009 and SAVE $200 4th Forum on Lab Informatics March 30 - April 1, 2009 Hyatt Harborside • Boston, MA Highlights of this program include: Evolution of an ELN: Lessons learned from 5 years of Cross-Disciplinary Integration Via Comprehensive • • ELN use at Merck Informatics Environments, A Case Study In Bridging Discovery And Pre-Clinical Development Use of ELN for Green Science at Eli Lilly and • Workflows Company Breaking Data Silos To Enable Integrated Safety • Biology ELN Applications to Pharmacokinetics • Assessment In Early Drug Discovery Featuring A Distinguished Speaker Faculty From: ABBOTT LABORATORIES ELI LILLY MEMORY PHARMACEUTICALS CORP AGILENT TECHNOLOGIES GEOMETRICK ENTERPRISES MERCK AND CO ATRIUM RESEARCH & CONSULTING INCYTE NATIONAL CENTER FOR BIOTECHNOLOGY INFORMATION (NCBI) BOSTON UNIVERSITY INSTITUTE FOR LABORATORY AUTOMATION NOVARTIS CAMBRIDGE SOFT JOHNSON & JOHNSON PFIZER CUBIST PHARMACEUTICALS AND MORE! Co-Sponsors: Panel Sponsor: Media Partner: TM Register Today! Call Sam 416-597 4719 or e-mail: sam.eid@iqpc.com
  2. 2. About Our Sponsors 4th Forum on Agilent Lab Informatics Technologies, a leading supplier of life science and chemical analysis instrumentation and services, provides solutions to pharmaceutical, March 30 - April 1, 2009 biopharmaceutical, environmental, foods & flavors, and hydrocarbon industries, Hyatt Harborside • Boston, MA making possible the identification, quantification and analysis of atomic, molecular, physical and biological applications. With a comprehensive informatics portfolio including: MetaboliteID and MassHunter Workstation, Dear Colleagues, Agilent addresses the needs of the pharmaceutical value chain with solutions in genomics, proteomics, metabolomics, According to a survey conducted by Atrium Research, laboratory scien drug development, QA/QC; and is ranked tists and technicians continue to be confront #1 in regulatory compliance. Agilent’s NEW ed by the ever-growing amount of data and information generated. Over 90 perc Kalabie Electronic Lab Notebook (ELN) is a ent of the survey respondents repo rt various data management challenges such paperless lab archive with a scalable, as locating information, data cons integrated platform for cross-team olidation or keeping up with the expanding data volume. collaboration. In an increasingly complex global environment, it simplifies and These multi-faceted challenges com accelerates the R&D process, and bined with technology improvemen ts have resulted in an increased need to use streamlines data management—all within LIMS & ELNs in drug discovery and early-stage a robust IP protection solution that development, to provide global acce ss for cross functional groups to leve complies with 21 CFR Part 11 rage work already done as well as to increase operating efficiency. requirements. IQPC’s 4th Laboratory Informatics CambridgeSoft conference is timed to bring toge ther valuable case studies, lessons learned and develops, markets best practices in combating these challenges of and services life science enterprise storing, organizing, consolidating and integrating different types of solutions for pharmaceutical, data from multiple systems. This event is bein g organized for all laboratory prof biotechnology, chemical companies and essionals actively involved in this area. academic research organizations. Software products include enterprise, workgroup and desktop versions of Chem & Bio Do not delay- register yourself and your team early to benefit from your Office, including Chem & Bio Draw, with early bird discounts! knowledge management (Chemistry, Biology, Process and Manufacturing E- I look forward to welcoming you Notebook & Compliant DB), chemical and at the conference! biological informatics (Inventory, BioAssay, Registration & Workflow LIMS), and With Kindest Regards, scientific database (ChemBioFinder Gateway, The Merck Index, ChemACX) solutions. Laura Hou Program Director, PharmaIQ, a division of IQPC laura.hou@iqpc.com Who You Will Meet: Director, R&D Informatics Director, Research Informatics Director, Discovery Informatics Special thanks to our program advisor Mr. Michael Elliott, CEO, Director of R&D Business Systems & Atrium Research & Consulting Process- Discovery Bioinformatics Group Leader Sponsorships and Exhibits are excellent opportunities for your company to Principal Scientist showcase its products and services to high-level, targeted decision makers attending the Senior Director, Chemistry conference. Pharma IQ and Lab Informatics 2009 will help companies like yours achieve Group Head, Pharma and Analytical sales, marketing and branding objectives by setting aside a limited number of event Development sponsorships and exhibit spaces – all of which are custom-tailored to help your company Director, Research Systems create a platform to maximize its exposure at the event. Senior Research Scientist For more information on Sponsoring and Exhibiting at Lab Informatics 2009, please Sr. Manager, IT – Analytical Chemistry contact Tom Boccard at 1-646-253-5517 or sponsorship@iqpc.com. Head of QA Compliance Register Today! Call Sam 416-597 4719 or e-mail: sam.eid@iqpc.com 2
  3. 3. Pre Conference ELN Master Class Monday, March 30, 2009 Give time to the issues that matter most! Sign up for the pre-conference master class series and dedicate more time to dialogue and networking in a classroom environment. This in-depth and interactive series of case studies will examine best practices and lessons learned from leading experts on utilizing different ELNs Registration & Coffee 10:30 Networking Break 8:15 Welcome & Chairman’s Opening Remarks 11:00 Outsourcing Testing – How It Complicates LIMS & 8:45 ELN Processes Discussing the Use of ELN for Green Science at Eli 9:00 Understanding the data setup for different situations • Lilly and Company Planning for getting that data back out • Creating a simple transition from paper to electronic Sharing collaborative ideas for achieving success in outsourcing • • Improving workflow management and informatics • Incorporating 12 principles of green chemistry into ELN • Gloria Metrick Michael E. Kopach LIMS Consultant Principal Research Scientist GEOMETRICK ENTERPRISES ELI LILLY AND COMPANY 11:45 Deploying ELN with LIMS to Automate Data Evolution of an ELN: Lessons Learned from 5 Years Management in Bioanalytical Development - Case 9:45 of ELN Use at Merck Study Will Focus on: Examining how governance and decision-making dictates what Initiating the process • • is in scope for ELN Evaluating deciding factors • Learning how to drive adoption of ELN through a research Identifying challenges and potential solutions • • organization Summarizing lessons learned • Discussing challenges and performance concerns of ELN Predicting future combinations of automated processes • • Summarizing the risks and benefits • Zachary Huggins Business Analyst 12:30 End of ELN Master Class MERCK AND CO Pre Conference Workshops Monday, March 30, 2009 12:45 – 3:00 (Lunch is included) A Successful Laboratory Informatics: A New Approach to the Development of a Laboratory Automation & Information Infrastructure Laboratory & scientific work has become dependent on intelligent What you will learn: instrumentation and information systems including LIMS & ELNs. Their • The structure of a successful laboratory automation & computing program, effective application is critical to the success of many companies. The • How that structure can lead to meeting compliance requirements, technological sophistication of today’s labs rival those of any IT organization How laboratory process modeling can improve the flow of data & • and managing that level of technology requires new skills. This workshop information both within the lab and between the lab and other will help you successfully develop and apply those skills. departments • How product and technology life-cycles can impact your labs and their How you will benefit: ability to implement a data life-cycle program. Learn how a new methodology can help your company develop a scientific information / automation infrastructure that can lead to: Workshop Leader: • successful system design & implementation, Joe Liscouski • reduced development and support costs, Director • improving the return on investments in programs, and, Institute for Laboratory Automation • providing a basis for technology, product, and data-life cycle management. 3:15 – 5:30 B Best Practices in the Selection of ELN Technology In the last five years, ELN technology has become pervasive across a wide What you will learn: range of laboratory types. This industry growth has spawned many new • The differences between commercially available ELN product types vendor offerings, often making it difficult for potential users to formulate a • Best practices in the selection of an ELN product product selection. Based on industry experience and best practice analysis, • Process modeling from a data perspective this workshop will help organizations formalize a process and approach to • How Use Cases streamline requirements development ELN product selection. • Approaches to return on investment (ROI) analysis • Methodologies for change acceleration How you will benefit: • An expedited product decision leading to a faster implementation Workshop Leader: • Improved probability of project success Michael H. Elliott • Ability to work with financial management on project justification CEO • Leverage the experiences of other organizations Atrium Research & Consulting Register Today! Call Sam 416-597 4719 or e-mail: sam.eid@iqpc.com 3
  4. 4. Main Conference Day One Tuesday, March 31, 2009 Registration & Coffee ELN is Deployed – What's Next? 8:15 1:00 Hearing the highs and the lows of the Merck ELN project, from • Welcome & Chairman’s Opening Remarks 8:45 the perspective of Merck scientists Understanding why today's ELN is falling short of an Electronic • Developing Biology ELN Applications to 9:00 Laboratory Environment Pharmacokinetics Discussing what's necessary to create a true Electronic • Managing in Vivo data and workflows inside a pharmacokinetic Laboratory Environment, and how pharmaceutical companies, • lab biotechs, and vendors can work together to make this a reality Sharing and integrating pharmacokinetic data with the rest of • Lori S Harmon R&D ELN Program Manager Enhancing collaboration across geographies (US vs. Europe) and • MERCK AND CO functions (Development vs. Discovery) Strengthening relationships as the foundation of project and • Cross-Disciplinary Integration via Comprehensive 1:45 business success Informatics Environments, a Case Study in Bridging Discovery and Pre-Clinical Development Kennan Marsh Workflows Director of Pre-Clinical Science, Global Pharmaceutical R&D ABBOTT LABORATORIES Discussing an approach to informatics systems that includes • comprehensive security, data management architecture and Yan Song integration with both internal and vendor supplied systems IT Program Manager, Global Pharmaceutical R&D Breaking down the silos created by LIMS, Electronic Lab • ABBOTT LABORATORIES Notebook, compound registration, screening, methods development and materials tracking systems Addressing the Variety of Analytical Techniques 9:45 Borrowing concepts used in other areas of IT such as ‘change • through A Simple-To-Use and Flexible ELN data capture’, ‘master data management’ and ‘business Covering from requests submission to analysis execution • intelligence’ reporting Analyzing dynamic forms design for individual technique • Focusing on the implementation of systems, embarking on a • Extending the workflow with OpenLAB ECM integration and • consolidated platform and seeing the benefits in cross functional smart import features integration throughout discovery and development areas Michael Burke Andrew Jacobson Solution Architect Director IBS, Research Informatics AGILENT TECHNOLOGIES CUBIST PHARMACEUTICALS 10:30 Networking Break Networking Break 2:30 11:00 Panel Session: The Integration of Informatics Breaking Data Silos to Enable Integrated Safety 3:00 Systems in an Analytical Laboratory Assessment in Early Drug Discovery Evaluating what data belongs in which system • Discussing how early safety assessment is necessary to improve • Identifying what should vendors do to enhance integration • quality and reduce attrition of clinical candidates Deciding what system should be used to hold final results • Summarizing how relevant data are generated by several groups • Moderator: within the company and need to be integrated to enable Chris Ruggles decision making Enterprise Marketing Focusing on the use of informatics and data integration to help • CAMBRIDGESOFT project teams mitigate cardio safety risks with examples from early lead discovery and optimization Panelists: Dmitri Mikhailov Yan Song Lab Head, Lead Discovery Informatics IT Program Manager, Global Pharmaceutical R&D NOVARTIS ABBOTT LABORATORIES Finding Convergent Technologies: Breaking Down Lori S Harmon 3:45 the Barriers between LIMS, ELN, and SDMS ELN Program Manager MERCK AND CO Discussing market trends and how they affect product decisions • Identifying differences and similarities between informatics • Andrew Jacobson architectures Director IBS, Research Informatics Streamlining workflow processes through a holistic approach • CUBIST PHARMACEUTICALS Discussing pros and cons of converged technology • Stanley Piper Evaluating the future of informatics: where do we go from here? • Senior Scientist, Global Research & Development Michael H. Elliott PFIZER CEO ATRIUM RESEARCH & CONSULTING 12:00 LUNCHEON FOR SPEAKERS & DELEGATES End of Day 1 4:30 Register Today! Call Sam 416-597 4719 or e-mail: sam.eid@iqpc.com 4
  5. 5. Main Conference Day Two Wednesday, April 1, 2009 Registration & Coffee number of tightly integrated discipline-specific systems as part of 8:15 a discovery/development productivity platform Welcome & Chairman’s Opening Remarks 8:45 Chris Leonard Director, Translational Research & Technology An ELN Evaluation: Determining If the Latest & 9:00 MEMORY PHARMACEUTICALS CORP Greatest Informatics Tool is a Good Fit Surveying the Land: principles in determining a commonly-held • 12:00 LUNCHEON FOR SPEAKERS & DELEGATES definition of the desired state Discussing three 2008 case studies of Work Order Management • Collaboration in an Academic Environment 1:00 (WOMS) / Electronic Laboratory Notebook (ELN) system Evolution of the electronic laboratory notebook • evaluations completed at Pfizer Pharmaceutical Sciences Creation of a publicly accessible chemical protocol database • Biologics Social networking in a collaborative research environment • Summarizing lessons learned • Scott E. Schaus Evaluating and identifying future direction • Associate Professor, Department of Chemistry Julie Spry BOSTON UNIVERSITY Principal Scientist PFIZER Discussing the ABCD Transactional Layer 1:45 Taking a quick tour of the ABCD transactional world – from • Using and Sharing Chemical Bioactivities in the 9:45 compound management to biological screening PubChem Database Discovering a unified framework for managing research data • Discussing what is PubChem - PubChem is a public information • Bridging the gap between the transactional and decision • resource for chemical structures and experimental biological support layers activity results Dimitris Agrafiotis Understanding the Molecular Libraries program - PubChem and • VP, Informatics many bioactivity screening laboratories are supported by the JOHNSON & JOHNSON NIH’s Molecular Libraries program Evaluating analysis tools provide chemical similarity searching • Networking Break 2:30 and structure-activity clustering Using information from databases - PubChem results from by • Meeting the needs of Formulation Group by 3:00 scientists outside the Molecular Libraries program are frequent Deploying Home Grown Electronic Inventory and and invited Formulation Number Systems Stephen H. Bryant Evaluating current solutions • Senior Investigator, Computational Biology Branch, National Measuring the effectiveness of current procedures set in place • Library of Medicine (NLM) Deciding whether to develop in-house solutions or to outsource • NATIONAL CENTER FOR BIOTECHNOLOGY INFORMATION Selecting the right vendor solutions: pros & cons • (NCBI) Dilip Modi 10:30 Networking Break Sr. Scientist INCYTE 11:00 Harnessing the Discovery Engine to Drive Informatics Techniques for Validation Development 3:45 Discovering when do you/don’t you do it Discussing the importance of resource management in small • • How to: pharma (both human resources and information resources) • - Increasing efficiency Addressing the information system needs of discovery scientists • - Decreasing time consumption of processes (chemists, biologists, etc.) provides a solid basis for driving the - Cutting cost by starting the process early drug development effort into the clinic Leveraging key workflows across disciplines through deploying a • End of Conference 4:30 Don’t Miss Out On Other Leading Pharmaceutical IQ’s Upcoming Events: 7th Lean Six Sigma for Pharmaceutical, Biotech and Medical Device Novel Oligonucleotides in Drug Development Excellence Philadelphia, PA; April 27th – 29th, 2009 February 23 - 25, 2009 * The Chemical Heritage Foundation Conference Center, Philadelphia, PA Software Design for Medical Device April 27 - 29, 2009 * Philadelphia, PA 3rd Annual Improving Solubility Uncovering novel advances in enhancing solubility, amorphous forms and 9th Contract Manufacturing bioavailability of drugs May 11-13, 2009, San Francisco, CA March 30 - April 01, 2009 * Hyatt Harborside at Boston's Logan International Airport, Boston, MA 4th Transportation & Biologics May 11-13, 2009, San Francisco, CA Register Today! Call Sam 416-597 4719 or e-mail: sam.eid@iqpc.com 5
  6. 6. 4th Forum on Lab Informatics March 30 - April 1, 2009 Hyatt Harborside • Boston, MA REGISTRATION CARD ( YES! Please register me for ❑ Conference Only ❑ Conference ❑ Conference ❑ Masterclass ❑ ALL ACCESS PASS + 1 Workshop + 2 Workshops Name ____________________________________________________________ Job Title _________________________________________________ Organization______________________________________________________ Approving Manager________________________________________ Address _____________________________________________ City________________________________________State__________Zip__________ Phone_____________________________________________E-mail____________________________________________________________________ ❑ Please keep me informed via email about this and other related events. ❑ Check enclosed for $_________ (Payable to IQPC) ❑ Charge my ❑ Amex ❑ Visa ❑Mastercard ❑ Diners Club Card #_______________________________Exp. Date___/___ ❑ I cannot attend, but please keep me informed of all future events. Venue Information Hyatt Harborside at Boston's Logan Group Rate-$179 (single/double occupancy) Please mention group code “IQPC” to ensure the International Airport special rate. 101 Harborside Drive Note that you are eligible for this rate three day Boston, MA 02128 prior and three days post the event. Direct: 617-568-1234 OR 800-233-1234 Fax: 617-568-6080 CUT OFF DATE for this offer is March 9, 2009. http://harborside.hyatt.com Registration Information END USERS SOLUTION PROVIDER 30-Jan-09 27-Feb-09 Standard Price 30-Jan-09 27-Feb-09 Standard Price after Feb. 27 after Feb. 27 Conference Only $1,399 $1,599 $1,799 Conference Only $1,999 $2,399 $2,799 Conference + 1 Workshop $1,948 $2,148 $2,348 Conference + 1 Workshop $2,548 $2,948 $3,348 Conference + 2 Workshop $2,497 $2,697 $2,897 Conference + 2 Workshop $3,097 $3,497 $3,897 Masterclass $749 $749 $749 Masterclass $749 $749 $749 ALL ACCESS PASS $2,997 $3,197 $3,397 ALL ACCESS PASS $3,597 $3,997 $4,397 Please note multiple discounts cannot be combined. Special Discounts Available: A limited number of discounts until payment is received and may be subject to cancellation. are available for the non-profit sector, government For IQPC’s Cancellation, Postponement and Substitution A $99 processing charge will be assessed to all organizations and academia. Policy, please visit www.iqpc.com/cancellation registrations not accompanied by credit card payment at . the time of registration. Note: Conference venue to be confirmed shortly. Please Details for making payment via EFT or wire transfer: check www.iqpc.com/us/solubility for updated information. MAKE CHECKS PAYABLE IN U.S. DOLLARS TO: IQPC JPMorgan Chase Special Dietary Needs: If you have a dietary restriction, * CT residents or people employed in the state of CT Penton Learning Systems LLC dba IQPC: 957-097239 please contact Customer Service at 1-800-882-8684 to must add 6% sales tax. ABA/Routing #: 021000021 discuss your specific needs. Reference: Please include the name of the attendee(s) and TEAM DISCOUNTS ©2009 IQPC. All Rights Reserved. The format, design, content the event number: 10367.003 For information on team discounts, please contact IQPC and arrangement of this brochure constitute a trademark of Payment Policy: Payment is due in full at the time of Customer Sam Eid at 416-597 4719 IQPC. Unauthorized reproduction will be actionable under the registration and includes lunches, refreshment and detailed e-mail sam.eid@iqpc.com Lanham Act and common law principles. conference materials. Your registration will not be confirmed Register Today! Call Sam 416-597 4719 or e-mail: sam.eid@iqpc.com 6

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