Trends in Healthcare
Investments and Exits - 2014
July 2014
Healthcare investments stabilize as IPOs surge
Trends in Healthcare Investments and Exits
http://www.svb.com/healthcare-re...
Table of Contents
4. Venture fundraising and investment drive innovation
14. Healthcare big exit M&A dips as IPOs surge
18...
Healthcare Accounts for 22 Percent of Total Venture
Investment
Trends in Healthcare Investments and Exits
http://www.svb.c...
Gap Between Capital Raised and Invested Narrows in
Recent Years Signaling Sustainability
Trends in Healthcare Investments ...
Corporate Venture Bolsters Early-Stage Biopharma
Companies
Trends in Healthcare Investments and Exits
http://www.svb.com/h...
Investment in Early-Stage Device Companies Lags
Trends in Healthcare Investments and Exits
http://www.svb.com/healthcare-r...
New Money in Biopharma Going to Early-Stage Companies
Trends in Healthcare Investments and Exits
http://www.svb.com/health...
Oncology is the Most Popular Indication
Trends in Healthcare Investments and Exits
http://www.svb.com/healthcare-report/ 9
Top New Money Corporate Investors in Biopharma
Trends in Healthcare Investments and Exits
http://www.svb.com/healthcare-re...
More than Half of New Money Biopharma Investments Were
in Pre-clinical or Phase I Companies
11
Trends in Healthcare Invest...
New Money in Device Spread Between Early-Stage and
Later-Stage Companies
12
Trends in Healthcare Investments and Exits
htt...
Ophthalmology and Orthopedic are the Most Popular
Indications
13
Trends in Healthcare Investments and Exits
http://www.svb...
The Year of the IPO: Big Exit M&A Dips as IPOs Surge
14
Trends in Healthcare Investments and Exits
http://www.svb.com/heal...
Healthcare Sees Record Potential IPO/Big Exit Returns
15
Trends in Healthcare Investments and Exits
http://www.svb.com/hea...
Biopharma Structured Deals Continue with Higher Upfront
Payments
16
Trends in Healthcare Investments and Exits
http://www....
Device Big Exit Activity Declines but Values Increase
17
Trends in Healthcare Investments and Exits
http://www.svb.com/hea...
Oncology is the Darling of BioPharma Big Exits
18
Trends in Healthcare Investments and Exits
http://www.svb.com/healthcare...
Half of Biopharma Big Exits Occurred at Phase III or
Commercial-Stage
19
Trends in Healthcare Investments and Exits
http:/...
Biopharma Big Exit M&A Activity Shifts to Later-Stage
Companies
20
Trends in Healthcare Investments and Exits
http://www.s...
Earlier-Stage Biopharma Companies are Opting for IPOs
over M&A
21
Trends in Healthcare Investments and Exits
http://www.sv...
BioPharma Big Exit M&A and IPOs Focus on Oncology and
Respiratory
22
Trends in Healthcare Investments and Exits
http://www...
Large Corporations Increase Biopharma Acquisitions
23
Trends in Healthcare Investments and Exits
http://www.svb.com/health...
Imaging/Diagnostics and Vascular Lead Device Big Exits
24
Trends in Healthcare Investments and Exits
http://www.svb.com/he...
Device Big Exits Decline Slightly
25
Trends in Healthcare Investments and Exits
http://www.svb.com/healthcare-report/
Bucking Convention, FDA Approval Not Necessary for Device
Big Exit
26
Trends in Healthcare Investments and Exits
http://ww...
Cardiovascular and Vascular Lead Trend of Non-FDA-
Approved Device Big Exits
27
Trends in Healthcare Investments and Exits...
This material, including without limitation the statistical information herein, is provided for
informational purposes onl...
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Trends in Healthcare Investments and Exits Presentation

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Silicon Valley Bank’s annual healthcare M&A report, Trends in Healthcare Investments and Exits, examines the merger and acquisition and IPO activity of private, venture-backed bio-pharma and medical device companies.
The study found that healthcare IPOs tripled in 2013, leading to record potential IPO/big exit returns of $12.5 billion.

For a detailed analysis access the report at: http://www.svb.com/healthcare-report_2014/.

**Slides updated on 8/4/2014

Published in: Healthcare
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  • Trends in Healthcare Investments and Exits Presentation

    1. 1. Trends in Healthcare Investments and Exits - 2014 July 2014
    2. 2. Healthcare investments stabilize as IPOs surge Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/ 2 The story of the healthcare venture industry in 2013 can be summed up in three words: initial public offerings. In a year in which the number of venture-capital backed healthcare IPOs tripled, public market enthusiasm helped stabilize venture investment and fundraising overall. It also led to increased valuations of big exit mergers and acquisitions. Venture investment in healthcare saw the biggest returns since SVB started tracking the data in 2005, reaching double the next best year. As we note in this report, the climate for IPOs is cooling. However, we see the current balanced financing ecosystem continuing to prime the innovation pump and encourage smooth capital flow to keep the industry humming. Silicon Valley Bank produces this annual report to guide our clients in decision- making and to contribute valuable insight into the top trends in the healthcare venture industry. We analyzed proprietary and public data and forecasts to determine trends at both ends of the pipeline: on the capital side through venture investment into companies and venture fundraising, and on the liquidity side through big exits and IPO activity.
    3. 3. Table of Contents 4. Venture fundraising and investment drive innovation 14. Healthcare big exit M&A dips as IPOs surge 18. Biopharma analysis: What’s hot, What’s not 24. Device analysis: What’s hot, What’s not 3
    4. 4. Healthcare Accounts for 22 Percent of Total Venture Investment Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/ 4
    5. 5. Gap Between Capital Raised and Invested Narrows in Recent Years Signaling Sustainability Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/ 5
    6. 6. Corporate Venture Bolsters Early-Stage Biopharma Companies Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/ 6
    7. 7. Investment in Early-Stage Device Companies Lags Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/ 7
    8. 8. New Money in Biopharma Going to Early-Stage Companies Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/ 8
    9. 9. Oncology is the Most Popular Indication Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/ 9
    10. 10. Top New Money Corporate Investors in Biopharma Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/ 10
    11. 11. More than Half of New Money Biopharma Investments Were in Pre-clinical or Phase I Companies 11 Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/
    12. 12. New Money in Device Spread Between Early-Stage and Later-Stage Companies 12 Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/?
    13. 13. Ophthalmology and Orthopedic are the Most Popular Indications 13 Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/
    14. 14. The Year of the IPO: Big Exit M&A Dips as IPOs Surge 14 Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/
    15. 15. Healthcare Sees Record Potential IPO/Big Exit Returns 15 Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/
    16. 16. Biopharma Structured Deals Continue with Higher Upfront Payments 16 Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/
    17. 17. Device Big Exit Activity Declines but Values Increase 17 Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/
    18. 18. Oncology is the Darling of BioPharma Big Exits 18 Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/
    19. 19. Half of Biopharma Big Exits Occurred at Phase III or Commercial-Stage 19 Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/
    20. 20. Biopharma Big Exit M&A Activity Shifts to Later-Stage Companies 20 Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/
    21. 21. Earlier-Stage Biopharma Companies are Opting for IPOs over M&A 21 Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/
    22. 22. BioPharma Big Exit M&A and IPOs Focus on Oncology and Respiratory 22 Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/
    23. 23. Large Corporations Increase Biopharma Acquisitions 23 Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/
    24. 24. Imaging/Diagnostics and Vascular Lead Device Big Exits 24 Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/
    25. 25. Device Big Exits Decline Slightly 25 Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/
    26. 26. Bucking Convention, FDA Approval Not Necessary for Device Big Exit 26 Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/
    27. 27. Cardiovascular and Vascular Lead Trend of Non-FDA- Approved Device Big Exits 27 Trends in Healthcare Investments and Exits http://www.svb.com/healthcare-report/
    28. 28. This material, including without limitation the statistical information herein, is provided for informational purposes only. The material is based in part upon information from third- party sources that we believe to be reliable, but which has not been independently verified by us and, as such, we do not represent that the information is accurate or complete. The information should not be viewed as tax, investment, legal or other advice nor is it to be relied on in making an investment or other decision. You should obtain relevant and specific professional advice before making any investment decision. Nothing relating to the material should be construed as a solicitation or offer, or recommendation, to acquire or dispose of any investment or to engage in any other transaction. ©2014 SVB Financial Group. All rights reserved. Silicon Valley Bank is a member of FDIC and Federal Reserve System. SVB>, SVB>Find a way, SVB Financial Group, and Silicon Valley Bank are registered trademark. Disclaimers 28

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