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Spio photo

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SHAPE Society

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Spio photo

  1. 1. Figure (1): NO production by Dextran coated vs. Lipid coated SPIO particles in Macrophages-24 h SPIO-4SPIO-2 SPIO-3 Control 0.0 0.1 0.2 0.3 SPIO-4 SPIO-2 SPIO-3 Control OD550(Nitritelevel)
  2. 2. 10.0 5.0 2.5 1.3 0.6 0.0 0 1 2 3 4 ug/mL FITC SPIO AFU/well±SD
  3. 3. Figure (3) A: macrophages harvested from mice injected with FITC-SPIO show intracellular fluorescence. The same panel stained with DAPI to show nuclear stain and viability. B: Circulating monocyte, shows iron particles (arrow), after the injection of SPIO. A B
  4. 4. Dark (negatively enhanced) aortic wall, full of iron particles Bright aortic lumen and wall without negative enhancement and no significant number of iron particles in pathology Before Injection After Injection (5 Days ) Apo E Deficient mouse C57B1 (control) mouse Figure 7:

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