Future Generations of
Merging of functional and structural
- Thermography and angiography
- Thermography and IVUS
Integration of therapy/diagnostics
Combination diagnostic and therapeutic applications
to a single catheter, ie, heat therapy
Lesion or artery specific treatment?
What do you believe would be safety
concerns related to heating?
What data would you need to see to prove
that heat treatment works?
If heating does work, minimally how long
should the effect last? And why?
Would you treat a stented culprit lesion or
artery? Or treat the non-culprit artery? Or
Post-Market Screening Tests
– Total cholesterol, LDL-cholesterol, TC-HDL distribution and
APO-E, Ox-LDL antibody, Lp-PLA2, LDL phenotype A, B, or
I, large particles: I-IIb, small particles: IIIa-IVb, IL-1, IL-6,
TNF-alfa, CRP, and ICAM-1
From the inflammatory markers
– Chlamydia pneumonia
– CMV, HSV1 and HSV2, mycoplasma pneumonia, hepatitis
A, helicobacter pylori,
– fibrinogen, systemic IL-6, E-selectin, P-selection, D-dimer,
albumin, sCD40-L, PAPP-A urine and blood