Organic Synth臼is;
The Disconnection Approach
        2日d Edition


                   Stuart 飞毛Tarre室主




               ...
This edition first published 2008
  2008 John 飞的 ley & Sons , Inc.

Registered 01.声
John 皆iley  & Sons   Ltd, τhe   Atrium...
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Co吕立f盟ts


Preface                                                                              lX

General References    ...
VH呈                                           Contents



33.             XV:τhe Use of Ketenes in                        ...
Preface

In the 26 years   since 有iley publìshed Organic              1于ze Disconnection Approach 色y Stuart
Warren ,由自 app...
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Organic synthesis the disconnection approach by stuart warren

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Organic synthesis the disconnection approach by stuart warren

  1. 1. Organic Synth臼is; The Disconnection Approach 2日d Edition Stuart 飞毛Tarre室主 vn Department, u瓦 ll. and 4a m Paul Wyatt he Schoolof of Bristol , U瓦 .c w w w :// tp ht ⑧WIL盯 AJohn 飞iVìley and Sons, Ltd" Publication
  2. 2. This edition first published 2008 2008 John 飞的 ley & Sons , Inc. Registered 01.声 John 皆iley & Sons Ltd, τhe Atrium , Southem Gate. Chichester,有部 t Suss帜, P019 8S龟 United Kingdom For details of our global 时itorial offices , for customer services and for infonnation about how to apply for permission to 陀use the copyri在ht material in this book please see our website at www.wiley.com. τhe right of the author to be identified as the author of this work has been asserted in accordance with the Copyright , Desi 盯1S and Patents Act 1988. A l rights reserved. N 0 P缸t of this publication 部ay be reproduced , stored in a retrieval system , or transmitted , in any fom1 or by any means , electronic , mechanical , photocopying , recording or otherwise , exc巳pt as by the UK Copyright , Designs and Patents Act 1988 噎 without the prior permissíon of the publisher. 认Tileyalso publishes its books in a variety of electronic formats. Some content that appears in print may not be avaHable in electronic books. vn Designations used by companies to distinguish their products are often daimed as trademarks. AH brand names and product names used in this book are trade 凶m时, service marks , trademarks or registered trademarks of their respective owners The publìsher is not associated with any product or v念ndor mentioned in this book. 丁his ll. ‘ publicatìon is designed to accurate and authoritative information in regard to the subject matter covered. 4a It is sold on the understanding that the publisher is not engaged in rendering professional services. If advice or other expert 揣在 istance is require丛 the services of cornpetent professional should be sough t. m The publísher and the author make no representations or warranties with respect to the accuracy or cornpleteness he of the contents of this work and 呼机ifically disclai 凯 all warranties , without limitation any implied warranties of 岳tness for a particular purpose. This work sold with the understanding that the pubhsher is not .c engaged in rendering services. τhe ad飞忧e and strategies contained herein rnay not be suitable for every situation. In view of ongoing research , equiprnent modifications , changes in govemmental regulation笃, and w the constant fiow of information relating to the use of experimental reagents , equipment警 and devices , the reader w is u塔ed to review and evaluate the information provided in the packagεinsert or instructions for each chemical , piece of equipment , reagent , or device for , arno只 g other things ‘ any changes in the instructions or índication of w usage and for added wamings and precautions. The fact that an organization or Website is referred to in this :// work as a citation andJor a potential source of further informatìon does not mean that the author or the publisher endorses the information the organization or Website may pro飞lide or recornmendations it may rnake. Furth时, tp readers should be aware that Internet Websites listed in this work may have changed or disappeared betw四只 ht when this work was written and when it is re我d. No waπanty may be created or extended by any promotional statements for this work. Neither the publisher nor the author shall be liable for any damages arising herefrom. LibraηI 0/ Congress C.αtaloging-in-Pl¥blication Data Warren哩 Stuart G. Organic synthesís : the disconnection approach I Stuart Warren and Paul Wyatt.一一 2nd ed. p. cm. Includes biblíographical references and index. ISBN 978-0-470-71237-5 (cloth)一-ISBN 978-0斗70-71236-8 (pbk. : alk. paper) 1. O~mic L 百yatt, PauL n. 在tle. QD262.W2842008 547'.2-dc22 2008033269 A catalogue record for this book is available from the British ISl日-l' 978-0-470-7份 12375 (HIB) 978-0-470平 12368 (P!B) τypeset in 10/12 Times-Roman by Laserwords Private Li mited , Chennai , India Printed and bound in Great Britain by CPI Antony Rowe, Chippenham, Wiltshire
  3. 3. first ac拿 &zt雹 霉 - 7 ¥ & stc A t ' 也 LHa c 的 di se , 巨 ih (a g Marrian 飞在rho L v 部 to r C Marria口,… 2007 , a 主 vn ll. 4a m he .c w w w :// tp ht
  4. 4. ht tp :// w w w .c he m 4a ll. vn
  5. 5. Co吕立f盟ts Preface lX General References XI 7730J5531 2. Basic and Synthesis of Aromatic li23345867 3. Strategy 1: The Order of Events 4. One-Group C-X Dìsconnections vn 5. Strate 2: v II: ll. 6. C-X DisconnectÎ ons 7. III: Reversal of Polarity , 4a of 8. Arnìn已 m 生 Strategy IV: Protecting he 10. One Group C C Disconnections 1: Alcohols … 11. General St栩如前r A: a Disconnection .c 12. Strate玄v V: w 2 w 1 2 i $ w 15. Alkene 1 · E A 16. Strategy VII: 盯se of (Alkynes) l :// i 2 · 17.τwo-Group C…C Disconnections 1: Diels-Ald时 Reactions tp 18. Strate 2: v VIII: Introduction to ht 在isconnections II: 豆 19. Compounds ' 20. IX: Control in Car柱。nvl Condensations 1 21. C-C Disconnections III: Compounds Conjugate (Michael) Addîtion and Robinson Annelation 151 22. X: 技itro 161 23. 在NφGroup Disconnections IV: Compounds 167 24. 177 25. Disconnections V: 185 26. Strategy XII: Reconnection 193 27. Two-Group C…C Disconn巳ctions VI: 199 28. General B: Strategy of Car七onyl Disconnections 207 29. XIII: Introduction to Synthesis: Saturated 217 30. Three品lernbered 229 3 1. XIV: 237 245
  6. 6. VH呈 Contents 33. XV:τhe Use of Ketenes in 251 34. Five-Mem如 ered 255 35. Strate Q. v XV I: Special Methods 2岳 1 36. Six-Membered Rings 269 37. General Strategy C: Synthesis 279 38. XVII: 289 39. AromatÍC 301 40. General D:A母 vanced 313 Index 325 vn ll. 4a m he .c w w w :// tp ht
  7. 7. Preface In the 26 years since 有iley publìshed Organic 1于ze Disconnection Approach 色y Stuart Warren ,由自 approach to the learning of synthesis has become while the book Ìtself is now dated in content and appearance ‘ In 唱Tiley published Organic and Control by Paul Wyatt and Stuart 轧Tarren. Thís muc如柱。ok ís as a fourth year und巳 rgradu时es and research workers in universities and industry. The workbook was published ìn 2008.τ如is new book made thεold one look very dated ín and content and gaps between what students were expectεd to understand in the 1980s vn and what are to understand now. This second edition is intended to fill some of those gaps. ll. The of the book is the same in the second edítion. It alternates chapters 4a new concepts wÌth strategy chapters that put 出e new work in the context of overall planning. 丁he 40 chapters have the same titles: some have hardly been changed whíle others m have a revision with considerable amounts of new m剖erial. In most cases from recent years are included. he One source of new material is the courses 出at the authors in the pharmaceutical .c Our 色asic course is 'The Disconnection Approach' and the 削aterial we have for this course has reinforced our attempts to reasons for the of the various compounds w which we 忧 lieve enlivens the 加ok and makes it more for students. We to w a second edítíon of the workbook after the publication of the w The 民rst edition of th巳 textbook was in fact thεthird in a series of 品。oks on :// by 乳 The firs t: The an lntroduction to 如 1974 , is a book asking for a of interaction with the reader who tp was to solve pro剖ems while rarely use now as the ht method has 岳阳 n suplersedt~d 七 y interactive programmes on computers. Paul Wyatt is writín革 an electronic book to replace The Cα rbonyl Group which will a of an electronic 七ook and 七ooks with associated workbooks in a uniform format that we hope will prove of value as students of organic develop their careers. Stuart 飞可arren and Paul 研rya生在 March 2008.
  8. 8. ht tp :// w w w .c he m 4a ll. vn
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  24. 24. ht tp :// w w w .c he m 4a ll. vn
  25. 25. ht tp :// w w w .c he m 4a ll. vn
  26. 26. ht tp :// w w w .c he m 4a ll. vn
  27. 27. ht tp :// w w w .c he m 4a ll. vn
  28. 28. ht tp :// w w w .c he m 4a ll. vn
  29. 29. ht tp :// w w w .c he m 4a ll. vn
  30. 30. ht tp :// w w w .c he m 4a ll. vn
  31. 31. ht tp :// w w w .c he m 4a ll. vn
  32. 32. ht tp :// w w w .c he m 4a ll. vn
  33. 33. ht tp :// w w w .c he m 4a ll. vn
  34. 34. ht tp :// w w w .c he m 4a ll. vn
  35. 35. ht tp :// w w w .c he m 4a ll. vn
  36. 36. ht tp :// w w w .c he m 4a ll. vn
  37. 37. ht tp :// w w w .c he m 4a ll. vn
  38. 38. ht tp :// w w w .c he m 4a ll. vn
  39. 39. ht tp :// w w w .c he m 4a ll. vn
  40. 40. ht tp :// w w w .c he m 4a ll. vn
  41. 41. ht tp :// w w w .c he m 4a ll. vn
  42. 42. ht tp :// w w w .c he m 4a ll. vn
  43. 43. ht tp :// w w w .c he m 4a ll. vn
  44. 44. ht tp :// w w w .c he m 4a ll. vn
  45. 45. ht tp :// w w w .c he m 4a ll. vn
  46. 46. ht tp :// w w w .c he m 4a ll. vn
  47. 47. ht tp :// w w w .c he m 4a ll. vn
  48. 48. ht tp :// w w w .c he m 4a ll. vn
  49. 49. ht tp :// w w w .c he m 4a ll. vn
  50. 50. ht tp :// w w w .c he m 4a ll. vn
  51. 51. ht tp :// w w w .c he m 4a ll. vn
  52. 52. ht tp :// w w w .c he m 4a ll. vn
  53. 53. ht tp :// w w w .c he m 4a ll. vn
  54. 54. ht tp :// w w w .c he m 4a ll. vn
  55. 55. ht tp :// w w w .c he m 4a ll. vn
  56. 56. ht tp :// w w w .c he m 4a ll. vn
  57. 57. ht tp :// w w w .c he m 4a ll. vn
  58. 58. ht tp :// w w w .c he m 4a ll. vn
  59. 59. ht tp :// w w w .c he m 4a ll. vn
  60. 60. ht tp :// w w w .c he m 4a ll. vn
  61. 61. ht tp :// w w w .c he m 4a ll. vn
  62. 62. ht tp :// w w w .c he m 4a ll. vn
  63. 63. ht tp :// w w w .c he m 4a ll. vn
  64. 64. ht tp :// w w w .c he m 4a ll. vn
  65. 65. ht tp :// w w w .c he m 4a ll. vn
  66. 66. ht tp :// w w w .c he m 4a ll. vn
  67. 67. ht tp :// w w w .c he m 4a ll. vn
  68. 68. ht tp :// w w w .c he m 4a ll. vn
  69. 69. ht tp :// w w w .c he m 4a ll. vn
  70. 70. ht tp :// w w w .c he m 4a ll. vn
  71. 71. ht tp :// w w w .c he m 4a ll. vn
  72. 72. ht tp :// w w w .c he m 4a ll. vn
  73. 73. ht tp :// w w w .c he m 4a ll. vn
  74. 74. ht tp :// w w w .c he m 4a ll. vn
  75. 75. ht tp :// w w w .c he m 4a ll. vn
  76. 76. ht tp :// w w w .c he m 4a ll. vn
  77. 77. ht tp :// w w w .c he m 4a ll. vn
  78. 78. ht tp :// w w w .c he m 4a ll. vn
  79. 79. ht tp :// w w w .c he m 4a ll. vn
  80. 80. ht tp :// w w w .c he m 4a ll. vn
  81. 81. ht tp :// w w w .c he m 4a ll. vn
  82. 82. ht tp :// w w w .c he m 4a ll. vn
  83. 83. ht tp :// w w w .c he m 4a ll. vn
  84. 84. ht tp :// w w w .c he m 4a ll. vn
  85. 85. ht tp :// w w w .c he m 4a ll. vn
  86. 86. ht tp :// w w w .c he m 4a ll. vn
  87. 87. ht tp :// w w w .c he m 4a ll. vn
  88. 88. ht tp :// w w w .c he m 4a ll. vn
  89. 89. ht tp :// w w w .c he m 4a ll. vn
  90. 90. ht tp :// w w w .c he m 4a ll. vn
  91. 91. ht tp :// w w w .c he m 4a ll. vn
  92. 92. ht tp :// w w w .c he m 4a ll. vn
  93. 93. ht tp :// w w w .c he m 4a ll. vn
  94. 94. ht tp :// w w w .c he m 4a ll. vn
  95. 95. ht tp :// w w w .c he m 4a ll. vn
  96. 96. ht tp :// w w w .c he m 4a ll. vn
  97. 97. ht tp :// w w w .c he m 4a ll. vn
  98. 98. ht tp :// w w w .c he m 4a ll. vn
  99. 99. ht tp :// w w w .c he m 4a ll. vn
  100. 100. ht tp :// w w w .c he m 4a ll. vn
  101. 101. ht tp :// w w w .c he m 4a ll. vn
  102. 102. ht tp :// w w w .c he m 4a ll. vn
  103. 103. ht tp :// w w w .c he m 4a ll. vn
  104. 104. ht tp :// w w w .c he m 4a ll. vn
  105. 105. ht tp :// w w w .c he m 4a ll. vn
  106. 106. ht tp :// w w w .c he m 4a ll. vn
  107. 107. ht tp :// w w w .c he m 4a ll. vn
  108. 108. ht tp :// w w w .c he m 4a ll. vn
  109. 109. ht tp :// w w w .c he m 4a ll. vn
  110. 110. ht tp :// w w w .c he m 4a ll. vn
  111. 111. ht tp :// w w w .c he m 4a ll. vn
  112. 112. ht tp :// w w w .c he m 4a ll. vn
  113. 113. ht tp :// w w w .c he m 4a ll. vn
  114. 114. ht tp :// w w w .c he m 4a ll. vn
  115. 115. ht tp :// w w w .c he m 4a ll. vn
  116. 116. ht tp :// w w w .c he m 4a ll. vn
  117. 117. ht tp :// w w w .c he m 4a ll. vn
  118. 118. ht tp :// w w w .c he m 4a ll. vn
  119. 119. ht tp :// w w w .c he m 4a ll. vn
  120. 120. ht tp :// w w w .c he m 4a ll. vn
  121. 121. ht tp :// w w w .c he m 4a ll. vn
  122. 122. ht tp :// w w w .c he m 4a ll. vn
  123. 123. ht tp :// w w w .c he m 4a ll. vn
  124. 124. ht tp :// w w w .c he m 4a ll. vn
  125. 125. ht tp :// w w w .c he m 4a ll. vn
  126. 126. ht tp :// w w w .c he m 4a ll. vn
  127. 127. ht tp :// w w w .c he m 4a ll. vn
  128. 128. ht tp :// w w w .c he m 4a ll. vn
  129. 129. ht tp :// w w w .c he m 4a ll. vn
  130. 130. ht tp :// w w w .c he m 4a ll. vn
  131. 131. ht tp :// w w w .c he m 4a ll. vn
  132. 132. ht tp :// w w w .c he m 4a ll. vn
  133. 133. ht tp :// w w w .c he m 4a ll. vn
  134. 134. ht tp :// w w w .c he m 4a ll. vn
  135. 135. ht tp :// w w w .c he m 4a ll. vn
  136. 136. ht tp :// w w w .c he m 4a ll. vn
  137. 137. ht tp :// w w w .c he m 4a ll. vn
  138. 138. ht tp :// w w w .c he m 4a ll. vn
  139. 139. ht tp :// w w w .c he m 4a ll. vn
  140. 140. ht tp :// w w w .c he m 4a ll. vn
  141. 141. ht tp :// w w w .c he m 4a ll. vn
  142. 142. ht tp :// w w w .c he m 4a ll. vn
  143. 143. ht tp :// w w w .c he m 4a ll. vn
  144. 144. ht tp :// w w w .c he m 4a ll. vn
  145. 145. ht tp :// w w w .c he m 4a ll. vn
  146. 146. ht tp :// w w w .c he m 4a ll. vn
  147. 147. ht tp :// w w w .c he m 4a ll. vn
  148. 148. ht tp :// w w w .c he m 4a ll. vn
  149. 149. ht tp :// w w w .c he m 4a ll. vn
  150. 150. ht tp :// w w w .c he m 4a ll. vn
  151. 151. ht tp :// w w w .c he m 4a ll. vn
  152. 152. ht tp :// w w w .c he m 4a ll. vn
  153. 153. ht tp :// w w w .c he m 4a ll. vn
  154. 154. ht tp :// w w w .c he m 4a ll. vn
  155. 155. ht tp :// w w w .c he m 4a ll. vn
  156. 156. ht tp :// w w w .c he m 4a ll. vn
  157. 157. ht tp :// w w w .c he m 4a ll. vn
  158. 158. ht tp :// w w w .c he m 4a ll. vn
  159. 159. ht tp :// w w w .c he m 4a ll. vn
  160. 160. ht tp :// w w w .c he m 4a ll. vn
  161. 161. ht tp :// w w w .c he m 4a ll. vn
  162. 162. ht tp :// w w w .c he m 4a ll. vn
  163. 163. ht tp :// w w w .c he m 4a ll. vn
  164. 164. ht tp :// w w w .c he m 4a ll. vn
  165. 165. ht tp :// w w w .c he m 4a ll. vn
  166. 166. ht tp :// w w w .c he m 4a ll. vn
  167. 167. ht tp :// w w w .c he m 4a ll. vn
  168. 168. ht tp :// w w w .c he m 4a ll. vn
  169. 169. ht tp :// w w w .c he m 4a ll. vn
  170. 170. ht tp :// w w w .c he m 4a ll. vn
  171. 171. ht tp :// w w w .c he m 4a ll. vn
  172. 172. ht tp :// w w w .c he m 4a ll. vn
  173. 173. ht tp :// w w w .c he m 4a ll. vn
  174. 174. ht tp :// w w w .c he m 4a ll. vn
  175. 175. ht tp :// w w w .c he m 4a ll. vn
  176. 176. ht tp :// w w w .c he m 4a ll. vn
  177. 177. ht tp :// w w w .c he m 4a ll. vn
  178. 178. ht tp :// w w w .c he m 4a ll. vn
  179. 179. ht tp :// w w w .c he m 4a ll. vn
  180. 180. ht tp :// w w w .c he m 4a ll. vn
  181. 181. ht tp :// w w w .c he m 4a ll. vn
  182. 182. ht tp :// w w w .c he m 4a ll. vn
  183. 183. ht tp :// w w w .c he m 4a ll. vn
  184. 184. ht tp :// w w w .c he m 4a ll. vn
  185. 185. ht tp :// w w w .c he m 4a ll. vn
  186. 186. ht tp :// w w w .c he m 4a ll. vn
  187. 187. ht tp :// w w w .c he m 4a ll. vn
  188. 188. ht tp :// w w w .c he m 4a ll. vn
  189. 189. ht tp :// w w w .c he m 4a ll. vn
  190. 190. ht tp :// w w w .c he m 4a ll. vn
  191. 191. ht tp :// w w w .c he m 4a ll. vn
  192. 192. ht tp :// w w w .c he m 4a ll. vn
  193. 193. ht tp :// w w w .c he m 4a ll. vn
  194. 194. ht tp :// w w w .c he m 4a ll. vn
  195. 195. ht tp :// w w w .c he m 4a ll. vn
  196. 196. ht tp :// w w w .c he m 4a ll. vn
  197. 197. ht tp :// w w w .c he m 4a ll. vn
  198. 198. ht tp :// w w w .c he m 4a ll. vn
  199. 199. ht tp :// w w w .c he m 4a ll. vn
  200. 200. ht tp :// w w w .c he m 4a ll. vn
  201. 201. ht tp :// w w w .c he m 4a ll. vn
  202. 202. ht tp :// w w w .c he m 4a ll. vn
  203. 203. ht tp :// w w w .c he m 4a ll. vn
  204. 204. ht tp :// w w w .c he m 4a ll. vn
  205. 205. ht tp :// w w w .c he m 4a ll. vn
  206. 206. ht tp :// w w w .c he m 4a ll. vn
  207. 207. ht tp :// w w w .c he m 4a ll. vn
  208. 208. ht tp :// w w w .c he m 4a ll. vn
  209. 209. ht tp :// w w w .c he m 4a ll. vn
  210. 210. ht tp :// w w w .c he m 4a ll. vn
  211. 211. ht tp :// w w w .c he m 4a ll. vn
  212. 212. ht tp :// w w w .c he m 4a ll. vn
  213. 213. ht tp :// w w w .c he m 4a ll. vn
  214. 214. ht tp :// w w w .c he m 4a ll. vn
  215. 215. ht tp :// w w w .c he m 4a ll. vn
  216. 216. ht tp :// w w w .c he m 4a ll. vn
  217. 217. ht tp :// w w w .c he m 4a ll. vn
  218. 218. ht tp :// w w w .c he m 4a ll. vn
  219. 219. ht tp :// w w w .c he m 4a ll. vn
  220. 220. ht tp :// w w w .c he m 4a ll. vn
  221. 221. ht tp :// w w w .c he m 4a ll. vn
  222. 222. ht tp :// w w w .c he m 4a ll. vn
  223. 223. ht tp :// w w w .c he m 4a ll. vn
  224. 224. ht tp :// w w w .c he m 4a ll. vn
  225. 225. ht tp :// w w w .c he m 4a ll. vn
  226. 226. ht tp :// w w w .c he m 4a ll. vn
  227. 227. ht tp :// w w w .c he m 4a ll. vn
  228. 228. ht tp :// w w w .c he m 4a ll. vn
  229. 229. ht tp :// w w w .c he m 4a ll. vn
  230. 230. ht tp :// w w w .c he m 4a ll. vn
  231. 231. ht tp :// w w w .c he m 4a ll. vn
  232. 232. ht tp :// w w w .c he m 4a ll. vn
  233. 233. ht tp :// w w w .c he m 4a ll. vn
  234. 234. ht tp :// w w w .c he m 4a ll. vn
  235. 235. ht tp :// w w w .c he m 4a ll. vn
  236. 236. ht tp :// w w w .c he m 4a ll. vn
  237. 237. ht tp :// w w w .c he m 4a ll. vn
  238. 238. ht tp :// w w w .c he m 4a ll. vn
  239. 239. ht tp :// w w w .c he m 4a ll. vn
  240. 240. ht tp :// w w w .c he m 4a ll. vn
  241. 241. ht tp :// w w w .c he m 4a ll. vn
  242. 242. ht tp :// w w w .c he m 4a ll. vn
  243. 243. ht tp :// w w w .c he m 4a ll. vn
  244. 244. ht tp :// w w w .c he m 4a ll. vn
  245. 245. ht tp :// w w w .c he m 4a ll. vn
  246. 246. ht tp :// w w w .c he m 4a ll. vn
  247. 247. ht tp :// w w w .c he m 4a ll. vn
  248. 248. ht tp :// w w w .c he m 4a ll. vn
  249. 249. ht tp :// w w w .c he m 4a ll. vn
  250. 250. ht tp :// w w w .c he m 4a ll. vn
  251. 251. ht tp :// w w w .c he m 4a ll. vn
  252. 252. ht tp :// w w w .c he m 4a ll. vn
  253. 253. ht tp :// w w w .c he m 4a ll. vn
  254. 254. ht tp :// w w w .c he m 4a ll. vn
  255. 255. ht tp :// w w w .c he m 4a ll. vn
  256. 256. ht tp :// w w w .c he m 4a ll. vn
  257. 257. ht tp :// w w w .c he m 4a ll. vn
  258. 258. ht tp :// w w w .c he m 4a ll. vn
  259. 259. ht tp :// w w w .c he m 4a ll. vn
  260. 260. ht tp :// w w w .c he m 4a ll. vn
  261. 261. ht tp :// w w w .c he m 4a ll. vn
  262. 262. ht tp :// w w w .c he m 4a ll. vn
  263. 263. ht tp :// w w w .c he m 4a ll. vn
  264. 264. ht tp :// w w w .c he m 4a ll. vn
  265. 265. ht tp :// w w w .c he m 4a ll. vn
  266. 266. ht tp :// w w w .c he m 4a ll. vn
  267. 267. ht tp :// w w w .c he m 4a ll. vn
  268. 268. ht tp :// w w w .c he m 4a ll. vn
  269. 269. ht tp :// w w w .c he m 4a ll. vn
  270. 270. ht tp :// w w w .c he m 4a ll. vn
  271. 271. ht tp :// w w w .c he m 4a ll. vn
  272. 272. ht tp :// w w w .c he m 4a ll. vn
  273. 273. ht tp :// w w w .c he m 4a ll. vn
  274. 274. ht tp :// w w w .c he m 4a ll. vn
  275. 275. ht tp :// w w w .c he m 4a ll. vn
  276. 276. ht tp :// w w w .c he m 4a ll. vn
  277. 277. ht tp :// w w w .c he m 4a ll. vn
  278. 278. ht tp :// w w w .c he m 4a ll. vn
  279. 279. ht tp :// w w w .c he m 4a ll. vn
  280. 280. ht tp :// w w w .c he m 4a ll. vn
  281. 281. ht tp :// w w w .c he m 4a ll. vn
  282. 282. ht tp :// w w w .c he m 4a ll. vn
  283. 283. ht tp :// w w w .c he m 4a ll. vn
  284. 284. ht tp :// w w w .c he m 4a ll. vn
  285. 285. ht tp :// w w w .c he m 4a ll. vn
  286. 286. ht tp :// w w w .c he m 4a ll. vn
  287. 287. ht tp :// w w w .c he m 4a ll. vn
  288. 288. ht tp :// w w w .c he m 4a ll. vn
  289. 289. ht tp :// w w w .c he m 4a ll. vn
  290. 290. ht tp :// w w w .c he m 4a ll. vn
  291. 291. ht tp :// w w w .c he m 4a ll. vn
  292. 292. ht tp :// w w w .c he m 4a ll. vn
  293. 293. ht tp :// w w w .c he m 4a ll. vn
  294. 294. ht tp :// w w w .c he m 4a ll. vn
  295. 295. ht tp :// w w w .c he m 4a ll. vn
  296. 296. ht tp :// w w w .c he m 4a ll. vn
  297. 297. ht tp :// w w w .c he m 4a ll. vn
  298. 298. ht tp :// w w w .c he m 4a ll. vn
  299. 299. ht tp :// w w w .c he m 4a ll. vn
  300. 300. ht tp :// w w w .c he m 4a ll. vn
  301. 301. ht tp :// w w w .c he m 4a ll. vn
  302. 302. ht tp :// w w w .c he m 4a ll. vn
  303. 303. ht tp :// w w w .c he m 4a ll. vn
  304. 304. ht tp :// w w w .c he m 4a ll. vn
  305. 305. ht tp :// w w w .c he m 4a ll. vn
  306. 306. ht tp :// w w w .c he m 4a ll. vn
  307. 307. ht tp :// w w w .c he m 4a ll. vn
  308. 308. ht tp :// w w w .c he m 4a ll. vn
  309. 309. ht tp :// w w w .c he m 4a ll. vn
  310. 310. ht tp :// w w w .c he m 4a ll. vn
  311. 311. ht tp :// w w w .c he m 4a ll. vn
  312. 312. ht tp :// w w w .c he m 4a ll. vn
  313. 313. ht tp :// w w w .c he m 4a ll. vn
  314. 314. ht tp :// w w w .c he m 4a ll. vn
  315. 315. ht tp :// w w w .c he m 4a ll. vn
  316. 316. ht tp :// w w w .c he m 4a ll. vn
  317. 317. ht tp :// w w w .c he m 4a ll. vn
  318. 318. ht tp :// w w w .c he m 4a ll. vn
  319. 319. ht tp :// w w w .c he m 4a ll. vn
  320. 320. ht tp :// w w w .c he m 4a ll. vn
  321. 321. ht tp :// w w w .c he m 4a ll. vn
  322. 322. ht tp :// w w w .c he m 4a ll. vn
  323. 323. ht tp :// w w w .c he m 4a ll. vn
  324. 324. ht tp :// w w w .c he m 4a ll. vn
  325. 325. ht tp :// w w w .c he m 4a ll. vn
  326. 326. ht tp :// w w w .c he m 4a ll. vn
  327. 327. ht tp :// w w w .c he m 4a ll. vn
  328. 328. ht tp :// w w w .c he m 4a ll. vn
  329. 329. ht tp :// w w w .c he m 4a ll. vn
  330. 330. ht tp :// w w w .c he m 4a ll. vn
  331. 331. ht tp :// w w w .c he m 4a ll. vn
  332. 332. ht tp :// w w w .c he m 4a ll. vn
  333. 333. ht tp :// w w w .c he m 4a ll. vn
  334. 334. ht tp :// w w w .c he m 4a ll. vn
  335. 335. ht tp :// w w w .c he m 4a ll. vn
  336. 336. ht tp :// w w w .c he m 4a ll. vn
  337. 337. ht tp :// w w w .c he m 4a ll. vn
  338. 338. ht tp :// w w w .c he m 4a ll. vn
  339. 339. ht tp :// w w w .c he m 4a ll. vn
  340. 340. ht tp :// w w w .c he m 4a ll. vn

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